Powder: -20°C for 3 years | In solvent: -80°C for 1 year
HTHQ (HTHQ(1-O-Hexyl-2,3,5-trimethylhydroquinone)), a hydroquinone monoalkyl ether, is an effective anti-oxidative agent. HTHQ is a potent anti-lipid-peroxidative compound and its antioxidation activity to be extremely elevated in biological systems, such as that of liver microsomes via the generation of stable free radicals.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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5 mg | 在庫あり | ¥ 7,000 | |||
10 mg | 在庫あり | ¥ 11,000 | |||
25 mg | 在庫あり | ¥ 14,000 | |||
50 mg | 在庫あり | ¥ 18,000 | |||
100 mg | 在庫あり | ¥ 22,500 | |||
200 mg | 在庫あり | ¥ 36,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 10,000 |
説明 | HTHQ (HTHQ(1-O-Hexyl-2,3,5-trimethylhydroquinone)), a hydroquinone monoalkyl ether, is an effective anti-oxidative agent. HTHQ is a potent anti-lipid-peroxidative compound and its antioxidation activity to be extremely elevated in biological systems, such as that of liver microsomes via the generation of stable free radicals. |
In vitro | HTHQ has an anti-oxidative activity similar to D,L-alpha-tocopherol against lipid peroxidation in linolate micelles initiated by addition of Fe2+. The anti-lipid-peroxidation activity of HTHQ is higher 4.8-fold than that of D,L-alpha-tocopherol against the peroxidation in phosphatidylcholine liposomes initiated by addition of Fe2+. [1] The effects of 0.02% Glu-P-1 or 0.03% MeIQx on the number and area of foci is significantly reduced by 0.125% HTHQ. [2] |
In vivo | Treatment with HTHQ potently inhibits PhIP-induced mammary carcinogenesis in female rats. Compared with DMN-induced hepatic fibrosis animals in the liver tissue, HTHQ reduced mRNA level of PDGF (Platelet-derived growth factor), α-SMA (α-smooth muscle actin) and TGF-β (transforming growth factor-β). In this study, we showed that HTHQ improves against DMN-induced liver fibrosis in male SD rats. |
別名 | HX 1171, HTHQ(1-O-Hexyl-2,3,5-trimethylhydroquinone), 1-O-hexyl-2,3,5-trimethylhydroquinone |
分子量 | 236.35 |
分子式 | C15H24O2 |
CAS No. | 148081-72-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 43 mg/mL(181.9 mM)
You can also refer to dose conversion for different animals. 詳細
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HTHQ 148081-72-5 Immunology/Inflammation Metabolism NF-Κb Reactive Oxygen Species HX 1171 BTT 105 BTT105 inhibit BTT-105 HTHQ(1-O-Hexyl-2,3,5-trimethylhydroquinone) HX-1171 1-O-hexyl-2,3,5-trimethylhydroquinone Inhibitor HX1171 inhibitor