Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Indobufen (Ibustrin) is an inhibitor of platelet aggregation and is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen suppresses thromboxane A2 (TxA2) synthesis. Indobufen down-regulates tissue factor (TF) in monocytes.
説明 | Indobufen (Ibustrin) is an inhibitor of platelet aggregation and is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen suppresses thromboxane A2 (TxA2) synthesis. Indobufen down-regulates tissue factor (TF) in monocytes. |
In vitro | Indobufen suppresses TxA2 but not PGE2 synthesis in LPS-stimulated monocytes. Indobufen causes the extent of ERK1/2 phosphorylation, whereas the levels of phosphorylated p38 are unaltered. Indobufen does not affect both Cox-1 and Cox-2 protein, whereas Indobufen reduces TxB2 levels. |
別名 | Ibustrin |
分子量 | 295.33 |
分子式 | C18H17NO3 |
CAS No. | 63610-08-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (186.23 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Indobufen 63610-08-2 Immunology/Inflammation Neuroscience COX Ibustrin Inhibitor inhibit Cyclooxygenase inhibitor