Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra Domain A domain. It can sensitize TRAIL-induced apoptosis by enhancing the expression of pro-apoptotic molecules in gastric cancer cells and has anti-cancer effects.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
10 mg | 在庫あり | ¥ 18,500 | |||
20 mg | 在庫あり | ¥ 27,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 16,000 |
説明 | Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra Domain A domain. It can sensitize TRAIL-induced apoptosis by enhancing the expression of pro-apoptotic molecules in gastric cancer cells and has anti-cancer effects. |
植物由来 |
分子量 | 360.31 |
分子式 | C18H16O8 |
CAS No. | 548-76-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 65 mg/mL(180.4 mM)
You can also refer to dose conversion for different animals. 詳細
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Irigenin 548-76-5 Cytoskeletal Signaling NF-Κb Integrin NF-κB inhibit cancer lung transition metastasis apoptosis Epithelial-Mesenchymal C-C TRAIL EDA gastric loop carcinoma Inhibitor inhibitor