Powder: -20°C for 3 years | In solvent: -80°C for 1 year
KGP94 is a potent, selective, and competitive inhibitor of the lysosomal endopeptidase enzyme.
説明 | KGP94 is a potent, selective, and competitive inhibitor of the lysosomal endopeptidase enzyme. |
In vitro | The novel cathepsin L/K inhibitors KGP94 could inhibit in vitro M2 macrophage invasion and reduce the macrophage-stimulated invasion of 4T1 murine breast cancer cells. KGP94 treatment also reduced the expression of several M2-associated markers, suggesting that cathepsin L activity may be important for IL-4-driven M0 to M2 differentiation[1]. |
別名 | KGP-94, KGP 94 |
分子量 | 350.23 |
分子式 | C14H12BrN3OS |
CAS No. | 1131456-28-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/ml (171.32 mM)
You can also refer to dose conversion for different animals. 詳細
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KGP94 1131456-28-4 Proteases/Proteasome Cysteine Protease KGP-94 Inhibitor M2 marker KGP 94 Metastasis Raw264.7 macrophage metastatic carcinoma Cathepsin inhibit prostate (PC-3ML) Cathepsin L breast cancer cell inhibitor