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Search Results for " Cathepsin "

ターゲット

125

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T6015	Cathepsin Inhibitor 1		Cysteine Protease
	Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.		Cysteine Protease
T37504L	Cathepsin D and E FRET Substrate acetate(839730-93-7 Free base)	Cathepsin D and E FRET Substrate acetate(839730-93-7 Free base)
	Cathepsin D and E FRET Substrate acetate is a fluorogenic substrate for cathepsins D and E but not for B, H, or L. Cathepsin D and E FRET Substrate acetate can be used in mechanistic studies on cathepsins D and E studies...
T60812	Cathepsin X-IN-1		Cysteine Protease
	Cathepsin X-IN-1 (compound 25) reduces the migration of PC-3 cell with low cytotoxic that is a potent inhibitor of Cathepsin X (IC 50 = 7.13 μM) [1].		Cysteine Protease
TQ0116	LY 3000328	Cathepsin S inhibitor	Cysteine Protease
	LY 3000328 (Cathepsin S inhibitor) is a potent, highly selective Cathepsin S (Cat S) inhibitor (IC50s: 7.7 and 1.67 nM for hCat S and mCat S).		Cysteine Protease
T3420	CA-074 methyl ester	Cathepsin B Inhibitor IV,CA-074Me	Cysteine Protease
	CA-074 methyl ester (Cathepsin B Inhibitor IV) is a specific inhibitor of Cathepsin B with neuroprotective, anti-cancer, and anti-inflammatory effects.		Cysteine Protease
T11554	Cathepsin Inhibitor 2		Cysteine Protease
	Cathepsin Inhibitor 2 is a potent Cathepsin S inhibitor (Ki: <20 nM).		Cysteine Protease
T38254	Cathepsin D and E FRET Substrate acetate
	Cathepsin D and E FRET Substrate acetate is a fluorogenic substrate selectively cleaved by cathepsins D and E at the Phe-Phe amide bond, without activity towards cathepsins B, H, or L. This specificity makes it an essent...
T37504	Cathepsin D and E FRET Substrate
	Mca-GKPILFFRL-Dpa-r-amide, FRET substrate for cathepsin D and E. Also cleaved by napsin A.
T80052	Cathepsin B
	Cathepsin B, a cysteine protease, plays a role in various forms of programmed cell death, such as apoptosis, pyroptosis, ferroptosis, necroptosis, and autophagic cell death [1].
T62659	Cathepsin C-IN-4
	Cathepsin C-IN-4 is a potent inhibitor (IC50: 65.6 nM) of histone C. Cathepsin C-IN-4 inhibits THP-1 cells (IC50: 203.4 nM) and U937 cells (IC50: 177.6 nM).
T64159	Cathepsin K inhibitor 2
	Cathepsin K inhibitor 2 is a potent inhibitor of cathepsin K. Cathepsin K (Cat K) is a cysteine protease expressed under the control of the CTSK gene, which is closely related to osteoporosis and hydrolyses collagen. cat...
T80333	Cathepsin G(1-5)
	Cathepsin G(1-5), an antimicrobial peptide identified within the clostripain-digested cathepsin G mixture [1], exhibits bactericidal properties.
T63854	Cathepsin C-IN-3
	Cathepsin C-IN-3 is a potent inhibitor of histone C (IC50: 61.79 nM) and also inhibits THP-1 cells (IC50: 101.5 nM) and U937 cells (IC50: 86.5 nM).
T62494	Cathepsin C-IN-5
	Cathepsin C-IN-5 (compound SF38) is a potent, selective, and orally active inhibitor of Cathepsin C, demonstrating IC50 values of 59.9 nM for Cat C, and showing significantly lower potency against Cat L (4.26 µM), Cat S,...
T72296	Cathepsin K inhibitor 3
	Cathepsin K Inhibitor 3, exhibiting an IC50 value of 0.5 nM, is a highly selective inhibitor of cathepsin K, featuring a favorable pharmacokinetic profile. It holds potential for use in studies of osteoarthritis (OA).
T79496	Cathepsin C-IN-6
	Cathepsin C-IN-6 (compound 2), an E-64c-hydrazideas-derived inhibitor of cathepsin C, possesses anti-inflammatory properties and impedes neutrophil elastase activation. This compound demonstrates potential efficacy in tr...
T38469	(Rac)-Z-Phe-Phe-FMK	Cathepsin L-IN-2	Beta Amyloid , Cysteine Protease
	(Rac)-Z-Phe-Phe-FMK (Cathepsin L-IN-2) is a cathepsin L inhibitor that inhibits the tendency of β-amyloid to induce apoptotic changes .		Beta Amyloid , Cysteine Protease
T72569	Cathepsin L/S-IN-1
	Cathepsin L/S-IN-1, a dual inhibitor targeting Cathepsin L and Cathepsin S, exhibits potent and selective inhibition with IC50 values of 4.10 μM and 1.79 μM, respectively. Demonstrating significant antimetastatic and inv...
T27989	MDK0734	Cathepsin B Inhinitor-42
	MDK0734 is a selective inhibitor of cathepsin B endopeptidase and exopeptidase activities.
T6432	Calpeptin		Apoptosis , Cysteine Protease , Proteasome
	Calpeptin is a potent, cell-permeable calpain inhibitor.		Apoptosis , Cysteine Protease , Proteasome
T28003	MDK7677	Cathepsin B Inhinitor-17,MDK 7677
	MDK7677 is a selective inhibitor of cathepsin B endopeptidase and exopeptidase activities.
T13288	VBY-825		Cysteine Protease
			Cysteine Protease
T27730	KGP94	KGP-94,KGP 94	Cysteine Protease
	KGP94 is an inhibitor of cysteine protease Cathepsin L(CTSL).		Cysteine Protease
T16777	ROC-325		Apoptosis , Autophagy
	ROC-325 is an effective and orally active inhibitor of autophagy with anticancer activity. ROC-325 induces renal cell carcinoma apoptosis and exhibits favorable selectivity.		Apoptosis , Autophagy
T12909	SID 26681509		Cysteine Protease , Parasite
			Cysteine Protease , Parasite
T0789	PMSF	Phenylmethylsulfonyl fluoride,Benzylsulfonyl fluoride	Serine Protease , Cysteine Protease
	Phenylmethanesulfonyl fluoride (PMSF (Phenylmethylsulfonyl fluoride)) is an enzyme inhibitor that inactivates IRC-50 arvin, subtilisin, and the fatty acid synthetase complex.		Serine Protease , Cysteine Protease
T21616	L-006235	L 006235	Cysteine Protease
	L-006235 is a potent and reversible inhibitor of cathepsin K with IC50 of 0.25 nM.		Cysteine Protease
T6035	Odanacatib	MK-0822	Cysteine Protease
	Odanacatib is an inhibitor of cathepsin K with potential anti-osteoporotic activity.		Cysteine Protease
T6738	Z-FA-FMK		SARS-CoV , Cysteine Protease
	Z-FA-FMK can irreversibly inhibit cysteine protease and also inhibit effector caspases.		SARS-CoV , Cysteine Protease
T1850	Balicatib	AAE581	Cysteine Protease
	Balicatib (AAE581) is a potent and selective inhibitor of cathepsin K, used in trials studying the treatment of osteoporosis.		Cysteine Protease
T7451	2-Cyanopyrimidine	2-cyano-Pyrimidine	Cysteine Protease
	2-Cyanopyrimidine (m-Hydroxyphenylpropionic acid) is inhibitor of cathepsin K(IC50 : 170 nM)		Cysteine Protease
T6040	Aloxistatin	E64d,Loxistatin,E64c ethyl ester	SARS-CoV , Cysteine Protease
	Aloxistatin (E64d) is an inhibitor of cysteine protease with blood platelet aggregation inhibiting activity. Aloxistatin is an irreversible, membrane-permeable inhibitor of lysosomal and cytosolic cysteine proteases with...		SARS-CoV , Cysteine Protease
TP1015	NFAT Inhibitor	VIVIT peptide	Others
	NFAT Inhibitor (VIVIT peptide) is a cell-permeable compound that selectively inhibits calcineurin-mediated dephosphorylation of NFAT.		Others
T6037	E-64	Proteinase inhibitor E 64,E 64,E64	Cysteine Protease , Antibacterial , Autophagy
	E-64 (Proteinase inhibitor E 64) is an irreversible and specific cysteine protease inhibitor. The IC50 of E-64 for papain is 9 nM.		Cysteine Protease , Antibacterial , Autophagy
T1885	Siramesine hydrochloride	Lu 28-179 hydrochloride	Ferroptosis , Sigma receptor , lysosomal autophagy
	Siramesine hydrochloride (Lu 28-179 hydrochloride) is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of Y cells and to exhibit a potent anticancer activity in vivo.		Ferroptosis , Sigma receptor , lysosomal autophagy
T6573	E 64c	NSC 694279,EP 475,Loxistatin Acid	SARS-CoV , Cysteine Protease
	E 64c (EP 475) , a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor.		SARS-CoV , Cysteine Protease
T10924	Cysteine protease inhibitor-2		Cysteine Protease
	Cysteine protease inhibitor 2 is a cysteine protease inhibitor. Cysteine protease inhibitor 2 inhibited DCT116 and PC3 cells with GI50 values of 6.5 μM and 4.4 μM, respectively.		Cysteine Protease
T3088	N-Ethylmaleimide	1-Ethyl-1H-pyrrole-2,5-dione,Ethylmaleimide,NEM	Cysteine Protease , DUB
	N-Ethylmaleimide (NEM) is a sulfhydryl reagent that is widely used in experimental biochemical studies.		Cysteine Protease , DUB
T4620	Siramesine	Lu 28-179	Sigma receptor
	Siramesine (Lu 28-179)(Lu 28-179) is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of cancer cells and to exhibit a potent anticancer activity in vivo.lysosome-destabilizing agent siram...		Sigma receptor
T12051	MIV-247		Cysteine Protease
	MIV-247 is a selective and potent inhibitor of cathepsin S (Kis 2.1, 4.2, and 7.5 nM for human, mouse, and wild monkey cathepsin S, respectively), which attenuates mechanical anomalies in preclinical models of neuropathi...		Cysteine Protease
T16394	ONO-5334		Cysteine Protease
	ONO-5334 is an effective and selective cathepsin K inhibitor (Ki: 0.10 nM, 0.049 nM, and 0.85 nM for human, rabbit, and rat cathepsin K, respectively). ONO-5334 has the potential for the study of osteoporosis.		Cysteine Protease
T16089	MK-0674		Cysteine Protease
	MK-0674 is an orally available, selective and potent cathepsin K inhibitor (IC50: 0.4 nM) that inhibits Cat B, Cat F, Cat L, and Cat S. It can be used in metabolism-related diseases.		Cysteine Protease
T21509	CA 074		Cysteine Protease
	CA 074 is a potent inhibitor of cathepsin B with a Ki value of 2 to 5 nM.CA 074 inhibits ischemic hippocampal neuronal death in primates and attenuates retinopathy and optic neuritis in experimental autoimmune encephalom...		Cysteine Protease
T41308L	Gly-Phe β-naphthylamide acetate	Gly-Phe β-naphthylamide acetate(21438-66-4 Free base)	Others
	Gly-Phe β-naphthylamide acetate is the substrate of Cathepsin C and can be used for research on the function of cathepsin C, intralysosomal hydrolysis and lysosomal membrane permeability.		Others
T19347	H-Arg-4MβNA	H-Arg-4MbNA	Others
	H-Arg-4MβNA (H-Arg-4MbNA) is a peptide that serves as a substrate for cathepsin H. The enzyme activity is often detected in gel electrophoresis.		Others
T8677	3,4 Dichloroisocoumarin		Others , Serine Protease , Cysteine Protease
	3,4 Dichloroisocoumarin is a granzyme, cathepsin G, and neutrolphil elastase inhibitor		Others , Serine Protease , Cysteine Protease
T12188	NB-360		BACE
			BACE
T5149	MC-Val-Cit-PAB		Others , AChR
	MC-Val-Cit-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate. FDA approved drugs such as brentuximab vedotin use this linker.		Others , AChR
TP2056L	Acetyl-Calpastatin (184-210)(human) acetate	Acetyl-Calpastatin (184-210) (human) acetate(123714-50-1 Free base )	Cysteine Protease
	Acetyl-Calpastatin (184-210)(human) acetate is a potent, selective and reversible calpain inhibitor with Ki values of 0.2 nM and 6 μM for µ-calpain and cathepsin L, respectively.		Cysteine Protease
T2639	LY2811376		Beta Amyloid , Beta-Secretase , BACE
	LY2811376, an orally available non-peptidic β-secretase(BACE1) inhibitor (IC50: 239-249 nM), can decrease Aβ secretion (EC50: 300 nM). It has 10-fold selectivity towards BACE1 over BACE2, and more than 50-fold inhibition...		Beta Amyloid , Beta-Secretase , BACE

Compounds

Cathepsin Inhibitor 1

T6015

Synonym:

Target: Cysteine Protease

Cathepsin D and E FRET Substrate acetate(839730-93-7 Free base)

T37504L

Synonym: Cathepsin D and E FRET Substrate acetate(839730-93-7 Free base)

Target: Cysteine Protease

LY 3000328

TQ0116

Synonym: Cathepsin S inhibitor

Target: Cysteine Protease

CA-074 methyl ester

T3420

Synonym: Cathepsin B Inhibitor IV,CA-074Me

Target: Cysteine Protease

Cathepsin Inhibitor 2

T11554

Synonym:

Target: Cysteine Protease

Cathepsin D and E FRET Substrate acetate

T38254

Synonym:

Target:

Cathepsin D and E FRET Substrate

Cathepsin K inhibitor 2

Cathepsin K inhibitor 3

Synonym: Cathepsin L-IN-2

Target: Beta Amyloid, Cysteine Protease

Synonym: Cathepsin B Inhinitor-42

Target: Apoptosis, Cysteine Protease, Proteasome

MDK7677

T28003

Synonym: Cathepsin B Inhinitor-17,MDK 7677

Target: Cysteine Protease

KGP94

T27730

Synonym: KGP-94,KGP 94

Target: Cysteine Protease

ROC-325

T16777

Synonym:

Target: Apoptosis, Autophagy

SID 26681509

T12909

Synonym:

Target: Cysteine Protease, Parasite

PMSF

T0789

Synonym: Phenylmethylsulfonyl fluoride,Benzylsulfonyl fluoride

Target: Serine Protease, Cysteine Protease

L-006235

T21616

Synonym: L 006235

Target: Cysteine Protease

Odanacatib

T6035

Synonym: MK-0822

Target: Cysteine Protease

Z-FA-FMK

T6738

Synonym:

Target: SARS-CoV, Cysteine Protease

Balicatib

T1850

Synonym: AAE581

Target: Cysteine Protease

2-Cyanopyrimidine

T7451

Synonym: 2-cyano-Pyrimidine

Target: Cysteine Protease

Aloxistatin

T6040

Synonym: E64d,Loxistatin,E64c ethyl ester

Target: SARS-CoV, Cysteine Protease

NFAT Inhibitor

TP1015

Synonym: VIVIT peptide

Target: Others

E-64

T6037

Synonym: Proteinase inhibitor E 64,E 64,E64

Target: Cysteine Protease, Antibacterial, Autophagy

Siramesine hydrochloride

T1885

Synonym: Lu 28-179 hydrochloride

Target: Ferroptosis, Sigma receptor, lysosomal autophagy

E 64c

T6573

Synonym: NSC 694279,EP 475,Loxistatin Acid

Target: SARS-CoV, Cysteine Protease

Cysteine protease inhibitor-2

T10924

Synonym:

Target: Cysteine Protease

N-Ethylmaleimide

T3088

Synonym: 1-Ethyl-1H-pyrrole-2,5-dione,Ethylmaleimide,NEM

Target: Cysteine Protease, DUB

Siramesine

T4620

Synonym: Lu 28-179

Target: Sigma receptor

MIV-247

T12051

Synonym:

Target: Cysteine Protease

ONO-5334

T16394

Synonym:

Target: Cysteine Protease

MK-0674

T16089

Synonym:

Target: Cysteine Protease

CA 074

T21509

Synonym:

Target: Cysteine Protease

Gly-Phe β-naphthylamide acetate

T41308L

Synonym: Gly-Phe β-naphthylamide acetate(21438-66-4 Free base)

3,4 Dichloroisocoumarin

T8677

Synonym:

Target: Others, Serine Protease, Cysteine Protease

Acetyl-Calpastatin (184-210)(human) acetate

TP2056L

Synonym: Acetyl-Calpastatin (184-210) (human) acetate(123714-50-1 Free base )

Target: Cysteine Protease

LY2811376

T2639

Synonym:

Target: Beta Amyloid, Beta-Secretase, BACE

カタログ番号	製品名	別名	ターゲット
T19503	Papain		Others , Cysteine Protease
	Papain is a cysteine protease of the peptidase C1 family. Papain is used in food, pharmaceutical, textile, and cosmetic industries.		Others , Cysteine Protease
TJS2216	Aurantiamide acetate	Asperglaucide	Cysteine Protease
	Aurantiamide acetate (Asperglaucide) was isolated from the fermentation broth of Aspergillus penicilloides for the first time. Aurantiamide acetate is a selective and orally active cathepsin inhibitor. Aurantiamide aceta...		Cysteine Protease
T6564	Leupeptin Hemisulfate		Serine Protease , Cysteine Protease
	Leupeptin hemisulfate is a protease inhibitor with cell membrane-permeable, reversible, competitive, and oral activities. Leupeptin hemisulfate inhibits the activity of Cathepsin B, Cathepsin H, and Cathepsin L, and bloc...		Serine Protease , Cysteine Protease
TN1249	3-Epiursolic acid		Cysteine Protease , Immunology/Inflammation related
	3-Epiursolic acid may have antiinflammatory activity, it shows inhibition on Cathepsins L (catL), the IC50 value of 6.5 μM, cathepsins L (catL) and B play an important role in tumor progression and have been considered p...		Cysteine Protease , Immunology/Inflammation related
T8709	Nandrolone phenylpropionate	Nandrolone phenpropionate	Androgen Receptor
	Nandrolone phenylpropionate (Nandrolone phenpropionate) is an androgen receptor agonist. It mainly used to treat women with breast cancer and osteoporosis		Androgen Receptor
T3417	Amentoflavone	Didemethyl-ginkgetin,Amenthoflavone,3',8''-Biapigenin	Apoptosis , P450 , Phospholipase , Reactive Oxygen Species , Opioid Receptor , COX , Antibacterial , RSV , Antifungal
	Amentoflavone (3',8''-Biapigenin), as a potent inhibitor of CYP3A4 and CYP2C9, can interact with many other medications. CYP3A4 and CYP2C9 are proteins used for drug metabolism in the body. Amentoflavone also is an inhib...
T19392	L-Homocysteine		Others
	L-Homocysteine, an L-configured homocysteine metabolite, induces the upregulation of cathepsin V, which mediates vascular endothelial inflammation in hyperhomocysteinaemia.		Others
T15702	Lactacystin		Proteasome
	Lactacystin is an antibiotic Streptomyces spp. the metabolite and is an effective and selective proteasome inhibitor (IC50: 4.8 μM for 20S proteasome). Lactacystin inhibits cell growth and induces neurite outgrowth and a...		Proteasome
T72898	Gallinamide A
	Gallinamide A is a potent inhibitor of cathepsin L with an IC 50 value of 17.6 pM.
TN2691	2',3'-Dehydrosalannol		BCL , Akt , Caspase
	2',3'-Dehydrosalannol possesses antifeedant activity against Spodptera litura. It shows anticancer effects on triple-negative breast cancer(TNBC), it inhibits cathepsin-mediated pro-survival signaling which resulted in g...		BCL , Akt , Caspase

天然物製品

Papain

T19503

Synonym:

Target: Others, Cysteine Protease

Aurantiamide acetate

TJS2216

Synonym: Asperglaucide

Target: Cysteine Protease

Leupeptin Hemisulfate

T6564

Synonym:

Target: Serine Protease, Cysteine Protease

3-Epiursolic acid

TN1249

Synonym:

Target: Cysteine Protease, Immunology/Inflammation related

Nandrolone phenylpropionate

T8709

Synonym: Nandrolone phenpropionate

Target: Androgen Receptor

Amentoflavone

T3417

Synonym: Didemethyl-ginkgetin,Amenthoflavone,3',8''-Biapigenin

Target: Apoptosis, P450, Phospholipase, Reactive Oxygen Species, Opioid Receptor, COX, Antibacterial, RSV, Antifungal

2',3'-Dehydrosalannol

TN2691

Synonym:

Target: BCL, Akt, Caspase

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-00735	Cathepsin S Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cathepsin S Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37 kDa and the accession number is P25774-1.
TMPY-00731	Cathepsin B Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cathepsin B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.2 kDa and the accession number is A0A024R374.
TMPY-02751	Cathepsin S Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Cathepsin S Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.6 kDa and the accession number is AAB94925.1.
TMPY-02450	Cathepsin D Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cathepsin D Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44 kDa and the accession number is P07339.
TMPH-02565	Cathepsin K Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Thiol protease involved in osteoclastic bone resorption. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thy...
TMPH-03262	Cathepsin K Protein, Rat, Recombinant (His)	Rat	E. coli
	Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in...
TMPY-00439	Cathepsin E Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	Cathepsin E Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.1 kDa and the accession number is AAH62002.1.
TMPH-01061	Cathepsin K Protein, Human, Recombinant (His)	Human	E. coli
	Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in...
TMPY-04503	Cathepsin B Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	Cathepsin B Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.1 kDa and the accession number is F7FAT8.
TMPY-02144	Cathepsin B Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Cathepsin B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.6 kDa and the accession number is P10605.
TMPH-01059	Cathepsin B Protein, Human, Recombinant (GST)	Human	E. coli
	Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Cleaves matrix extracellular phosphoglycoprotein MEPE. Involved in the solubilization of cross-linked TG/thyroglobuli...
TMPY-00362	Cathepsin S Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	Cathepsin S Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.3 kDa.
TMPY-02699	Cathepsin Z Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cathepsin Z Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33 kDa and the accession number is Q9UBR2.
TMPY-04081	Cathepsin H Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Proinflammatory cytokines decreased the expression of CTSH in human islets and primary rat beta-cells, and overexpression of CTSH protected insulin-secreting cells against cytokine-induced apoptosis. Cathepsin H Protein,...
TMPH-03263	Cathepsin Z Protein, Rat, Recombinant (His & SUMO)	Rat	E. coli
	Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity. Capable of producing kinin potentiating peptides.
TMPY-01699	Cathepsin E Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Cathepsin E Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.4 kDa and the accession number is P70269.
TMPY-00733	Cathepsin D Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Cathepsin D Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.4 kDa and the accession number is P18242.
TMPY-01450	Cathepsin A Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Cathepsin A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.8 kDa and the accession number is P16675-1.
TMPH-03261	Cathepsin D Protein, Rat, Recombinant (His & Myc)	Rat	E. coli
	Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation. Cathepsin D Protein, Rat, Recombinant (His & Myc) is exp...
TMPY-02171	Cathepsin L Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Cathepsin L Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.3 kDa and the accession number is P06797.
TMPH-01060	Cathepsin F Protein, Human, Recombinant (His)	Human	E. coli
	Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis. Cathepsin F Protein, Human, Recombinant (His) is expressed...
TMPH-01063	Cathepsin O Protein, Human, Recombinant (His & Myc)	Human	HEK293 Cells
	Proteolytic enzyme possibly involved in normal cellular protein degradation and turnover. Cathepsin O Protein, Human, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predic...
TMPH-02566	Cathepsin W Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	May have a specific function in the mechanism or regulation of T-cell cytolytic activity. Cathepsin W Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The pre...
TMPY-01249	Cathepsin V Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cathepsin V (CTSV), also known as Cathepsin L2, CTSL2, and CATL2, is a member of the peptidase C1 family. It is predominantly expressed in the thymus and testis. Cathepsin V is also expressed in corneal epithelium, and t...
TMPY-00734	Cathepsin L Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cathepsin L Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.3 kDa and the accession number is A0A024R276.
TMPH-00437	Cathepsin D Protein, Cricetulus griseus, Recombinant (His & SUMO)	Chinese hamster	E. coli
	N/A. Cathepsin D Protein, Cricetulus griseus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 53.3 kDa and the accession number is G3I4W7.
TMPY-00736	Cathepsin Z Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Cathepsin Z Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.2 kDa and the accession number is Q545I6.
TMPH-01062	Cathepsin O Protein, Human, Recombinant (E. coli, His & Myc)	Human	E. coli
	Proteolytic enzyme possibly involved in normal cellular protein degradation and turnover. Cathepsin O Protein, Human, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag...
TMPY-00730	Cathepsin A Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cathepsin A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 53 kDa and the accession number is P10619-1.
TMPY-06479	Cathepsin H Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Proinflammatory cytokines decreased the expression of CTSH in human islets and primary rat beta-cells, and overexpression of CTSH protected insulin-secreting cells against cytokine-induced apoptosis. Cathepsin H Protein,...
TMPH-00134	AcMNPV Viral cathepsin Protein (His & SUMO)	AcMNPV	E. coli
	Cysteine protease that plays an essential role in host liquefaction to facilitate horizontal transmission of the virus. Accumulates within infected cells as an inactive proenzyme (proV-CATH), which is activated by proteo...
TMPH-02628	Cathepsin C Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Thiol protease. Has dipeptidylpeptidase activity. Can act as both an exopeptidase and endopeptidase. Can degrade glucagon. Plays a role in the generation of cytotoxic lymphocyte effector function.
TMPH-00060	ApNPV Viral cathepsin Protein (His & Myc)	ApNPV	E. coli
	Cysteine protease that plays an essential role in host liquefaction to facilitate horizontal transmission of the virus. May participate in the degradation of foreign protein expressed by the baculovirus system. ApNPV Vir...
TMPY-00732	Cathepsin C Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cathepsins are proteases found in many types of cells conserved in all animals, which have a vital role in mammalian cellular turnover such as bone resorption. The lysosomal cysteine protease Cathepsin C (CTSC), also kno...
TMPJ-00845	CTSE Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cathepsin E (CTSE) is a gastric aspartyl protease that functions as a disulfide-linked homodimer. It is a member of the Peptidase C1 family, and has a specificity similar to that of Pepsin A and Cathepsin D. CTSE is loca...
TMPJ-00497	CTSB Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cathepsin B is an enzymatic protein belonging to the peptidase (or protease) families. The protein encoded by this gene is a lysosomal cysteine protease composed of a dimer of disulfide-linked heavy and light chains, bot...
TMPJ-00508	CTSL Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cathepsin L is an enzyme. Cathepsin L, a lysosomal endopeptidase expressed in most eukaryotic cells, is a member of the papain-like family of cysteine proteinases. Cathepsin L plays a major role in antigen processing, tu...
TMPY-00672	Azurocidin/CAP37 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Azurocidin (AZU1), also known as heparin-binding protein (HBP) or cationic antimicrobial protein 37 (CAP37), is an azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. The Azurophil...
TMPJ-01204	TPSAB1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Tryptases are serine proteases with trypsin-like specificity. Together with chymases and Cathepsin G, tryptases are important players in mast cell mediation of inflammatory and allergic responses. Tryptase alpha/beta-1(T...
TMPJ-00708	CST7 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Mouse Cystatin F belongs to cystatin superfamily, which encompasses proteins that contain multiple cystatin-like sequences. It has been shown that Cystatin F is selectively expressed by hematopoietic cells and may be a b...
TMPY-01644	Cystatin S Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cystatin-S, also known as Cystatin-4, Salivary acidic protein 1, Cystatin-SA-III and CST4, is a secreted protein which belongs to thecystatin family. Cystatin-4 / CST4 is expressed in submandibular and sublingual sali...
TMPJ-01287	Sialidase-1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Sialidase-1 belongs to the N-acetyl-a neuraminidase family. Sialidase-1 is expressed in many tissues; it is highly expressed in the pancreas, and weakly expressed in the brain. Sialidase-1 is a lysosomal enzyme, which cl...
TMPJ-00869	GLB1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	β Galactosidase is a lysosomal β Galactosidase that hydrolyzes the terminal β Galactose from Ganglioside and Keratan sulfate. In lysosome, the mature β Galactosidase protein associates with Cathepsin A and Neuraminidase ...
TMPY-00729	Cystatin D Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cystatins are natural inhibitors of papain-like (family C1) and legumain-related (family C13) cysteine peptidases. The mammalian cystatin superfamily members are of three major types, including the type 1 cystatins (stef...
TMPY-01303	Serpin A3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	SerpinA3, also known as Alpha 1-antichymotrypsin (AACT), is a plasma alpha globulin glycoprotein, and is a member of serpin superfamily of the serine protease inhibitors consisting of at least 35 members. SerpinA3 has be...
TMPY-02717	GPR37 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	GPR37 (cathepsin Z) is an orphan receptor that belongs to the G-protein coupled receptor 1 family. G protein-coupled receptors are a large protein family comprised of transmembrane receptors that sense molecules outside ...
TMPY-02242	Serpin B6 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	SerpinB6, also known as Cytoplasmic antiproteinase, Peptidase inhibitor 6, Placental thrombin inhibitor, SERPINB6 and PI-6, is a cytoplasm protein that belongs to the serpin family and Ov-serpin subfamily. SerpinB6 / PI-...
TMPY-01027	Mast Cell Protease-1/MCPT-1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Mast Cell Protease 1 (MMCP-1), also known as MCP-1, MCPT-1 and β-chymase, is a member of the Chymase family of chymotrypsin-like serine proteases. MCPT-1 is a 26 kDa β-chymase that is a component of mast cell granules. I...