Powder: -20°C for 3 years | In solvent: -80°C for 1 year
L-Lactic acid ((S)-2-Hydroxypropanoic acid) is a natural product produced by the anaerobic glycolysis of pyruvic acid. L-Lactic acid is a sensitive indicator of tissue hypoxia and can be used as a hemodynamic indicator in critically ill patients.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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500 mg | 在庫あり | ¥ 9,500 | |||
1 g | 在庫あり | ¥ 11,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 10,500 |
説明 | L-Lactic acid ((S)-2-Hydroxypropanoic acid) is a natural product produced by the anaerobic glycolysis of pyruvic acid. L-Lactic acid is a sensitive indicator of tissue hypoxia and can be used as a hemodynamic indicator in critically ill patients. |
In vitro |
METHODS: Mouse CD4+CD25-T cells were treated with low-glucose medium containing L-Lactic acid (5-20 mM), and Teff proliferation was detected by Flow cytometry. RESULTS: L-Lactic acid had a sustained inhibitory effect on T cell proliferation, and apoptosis-independent effect. [1] METHODS: T cells were cultured in medium containing L-Lactic acid (20 mM), and ROS levels were measured using ROS and superoxide detection assay kits. RESULTS: A significant reduction in ROS and O2- production was observed in L-Lactic acid-treated T cells. [2] |
In vivo |
METHODS: To study its effect on swimming endurance, L-Lactic acid (25-50 mg/kg in 0.9% NaCl) was administered intraperitoneally to ICR mice. RESULTS: L-Lactic acid enhanced the swimming endurance of mice, and the effect was dose-dependent. [3] METHODS: To investigate the effect on endotoxemia, L-Lactic acid (80 mg/kg) was intraperitoneally injected into mice, and 20 h later, a lethal dose of LPS (25 mg/kg) was intraperitoneally injected into mice to induce infectious shock. RESULTS: L-Lactic acid significantly inhibited LPS-induced cytokine induction in mice following endotoxemia.L-Lactic acid treatment decreased glucose uptake and lactate output during LPS stimulation. [4] |
別名 | 2-HYDROXYPROPIONIC ACID, L-(+)-Lactic acid, (S)-2-Hydroxypropanoic acid |
分子量 | 90.08 |
分子式 | C3H6O3 |
CAS No. | 79-33-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (555.06 mM)
Saline: 90.08 mg/mL (555.06 mM)
You can also refer to dose conversion for different animals. 詳細
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L-Lactic acid 79-33-4 Metabolism Microbiology/Virology Antibacterial Endogenous Metabolite Antibiotic Inhibitor inhibit 2-HYDROXYPROPIONIC ACID LLactic acid L Lactic acid L-(+)-Lactic acid 2-Hydroxypropanoic acid (S)-2-Hydroxypropanoic acid Bacterial inhibitor