Powder: -20°C for 3 years | In solvent: -80°C for 1 year
LY2365109 hydrochloride is a potent and selective GlyT1 inhibitor, with an IC50 of 15.8 nM for glycine uptake in cells over-expressing hGlyT1a.
説明 | LY2365109 hydrochloride is a potent and selective GlyT1 inhibitor, with an IC50 of 15.8 nM for glycine uptake in cells over-expressing hGlyT1a. |
ターゲット&IC50 | GlyT1 (human):15.8 nM nM |
In vivo | LY2365109 hydrochloride increases seizure thresholds in mice[2].LY2365109 hydrochloride (0.3-30 mg/kg; p.o.) produces dose-dependent elevations in CSF levels of glycine[1].? |
分子量 | 421.91 |
分子式 | C22H28ClNO5 |
CAS No. | 1779796-27-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 30 mg/mL (71.11 mM)
You can also refer to dose conversion for different animals. 詳細
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LY2365109 hydrochloride 1779796-27-8 Neuroscience GlyT neuroblastoma Glycine transporters LY2365109 Human LY2365109 Hydrochloride LY-2365109 hydrochloride LY 2365109 LY-2365109 Hydrochloride glycine seizure LY-2365109 uptake LY 2365109 Hydrochloride Inhibitor inhibit inhibitor