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カタログ番号 | 製品名 | 別名 | ターゲット |
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T15130 | Dilazep dihydrochloride | Others | |
Dilazep dihydrochloride is an adenosine uptake inhibitor. It also inhibits ischemic damage, membrane transport of nucleosides, and platelet aggregation. It has cerebral and coronary vasodilating action through the enhanc... | |||
T9031 | MCU-i4 | Others , Mitochondrial Metabolism | |
MCU-i4 is a novel negative modulator of the MCU, binding MICU1 and impairing muscle cell growth. | |||
T11064 | DMT1 blocker 2 | Others | |
DMT1 blocker 2, compound 12f, is a direct inhibitor of divalent metal transporter 1 (DMT1) with an IC50 hydrogen peroxide value of 0.83, which is expected to block iron uptake by intestinal epithelial cells in vivo. | |||
T4534 | BMS-309403 | FABP | |
BMS-309403 is an effective, selective and cell-permeable inhibitor of fatty acid binding protein 4 (FABP4) with a Ki of less than 2 nM. | |||
T15802 | LY2183240 | FAAH , Autophagy | |
LY2183240 inhibits fatty acid amide hydrolase (FAAH) activity (IC50 = 12.4 nM). LY2183240 is a novel and highly effective blocker of anandamide uptake (IC50 = 270 pM). | |||
T5345 | V-9302 | Others | |
V-9302 (V9302) is a competitive antagonist of transmembrane glutamine flux that selectively and potently targets the amino acid transporter ASCT2 (IC50: 9.6 uM). | |||
T23070 | Nisoxetine hydrochloride | Sodium Channel , Monoamine Transporter , Norepinephrine | |
Nisoxetine hydrochloride is a noradrenaline transporter (NET) inhibitor | |||
T12931 | SLC13A5-IN-1 | Stearoyl-CoA Desaturase (SCD) | |
T14327 | AS1949490 | Phosphatase | |
AS1949490 activated glucose metabolism via up-regulation of GLUT1 gene in L6 myotubes[1][2]. AS1949490 is a potent and selective SHIP-2 (SH2 domain-containing inositol 5′ phosphatase 2) inhibitor, with an IC50 of 620 nM. | |||
T11908 | LY2365109 hydrochloride | GlyT | |
LY2365109 hydrochloride is a potent and selective GlyT1 inhibitor, with an IC50 of 15.8 nM for glycine uptake in cells over-expressing hGlyT1a. | |||
T14496 | BAMB-4 | ITPKA-IN-C14 | Others |
BAMB-4 (ITPKA-IN-C14) is a highly membrane-permeable inhibitor of inositol-1,4,5-trisphosphate-3-kinase A (ITPKA). It acts by suppressing the metastasis-promoting effect of ITPKA in lung tumor cells(with IC50 of 37 μM in... | |||
T12306 | OMDM-5 | Cannabinoid Receptor , Endogenous Metabolite , TRP/TRPV Channel | |
OMDM-5 is a selective anandamide cellular uptake (ACU)inhibitor(Ki of 4.8 μM). | |||
T39429 | AHN 1-055 hydrochloride | 3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride | Dopamine Receptor |
AHN 1-055 hydrochloride (3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride) is an inhibitor of dopamine transporter (DAT) and dopamine uptake(IC50 = 71 nM). | |||
T8702 | SKF-83566 | Dopamine Receptor , 5-HT Receptor , AChR | |
SKF-83566 is a blood-brain permeable and orally active antagonist of D1-like dopamine receptor and a weaker competitive 5-HT2 receptor antagonist with Ki of 11 nM | |||
T3470 | Cis-ACBD | cis-1-aminocyclobutane-1,3-dicarboxylic acid | Amino Acids and Derivatives |
Cis-ACBD (cis-1-aminocyclobutane-1,3-dicarboxylic acid) is a potent and selective N-methyl-D-aspartate receptor agonist. | |||
T1233 | Oxolinic acid | Emyrenil,Nidantin,NSC 110364,Dioxacin,Urinox | Dopamine Receptor , DNA/RNA Synthesis , Antibacterial , Antibiotic |
Oxolinic acid (Nidantin) is a synthetic antimicrobial related to NALIDIXIC ACID and used in URINARY TRACT INFECTIONS. | |||
T12302 | OMDM-1 | (Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide | Endogenous Metabolite |
OMDM-1 ((Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide) is a selective and metabolically stable anandamide cellular uptake (ACU)inhibitor with a Ki of 2.4 μM. | |||
T22276 | Bis(maltolato)oxovanadium(IV) | BMOV,Bis maltolato oxovanadium,Bis(maltolato)oxovanadium (IV),bis maltolato oxo vanadium,Bis(maltolato)oxovanadium (IV) | Phosphatase , Others |
Bis(maltolato)oxovanadium(IV) (BMOV) is a potent, reversible, competitive and orally active pan-PTP (protein tyrosine phosphatases)inhibitor with insulin-mimicking effects and anti-diabetic properties. BMOV is a potent i... | |||
T0031L | Ziprasidone hydrochloride | CP-88059 hydrochloride,CP-88059,Ziprasidone HCl | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Norepinephrine , Histamine Receptor |
Ziprasidone hydrochloride (CP-88059 hydrochloride) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic activity. | |||
T7153 | Vanoxerine dihydrochloride | GBR-12909 dihydrochloride,I893 dihydrochloride | Dopamine Receptor |
Vanoxerine dihydrochloride (GBR-12909 dihydrochloride) is a potent inhibitor that blocks dopamine uptake (IC50 : 1-51 nM) | |||
T0313 | Evans blue | Direct Blue 53,C.I. 23860 | GluR |
Evans blue (C.I. 23860) is an azo dye, inhibits L-glutamate uptake via the membrane-bound excitatory amino acid transporter (EAAT). | |||
T23119 | Palmitoylisopropylamide | FAAH | |
Palmitoylisopropylamide is a selective FAAH inhibitor that inhibits [H]-AEA uptake and cell proliferation at low concentrations. | |||
T69013 | Alaproclate | ||
Alaproclate is a specific 5-hydroxytryptamine uptake inhibitor and antidepressant. | |||
T20953 | Lumiflavine | Lumilactoflavin,Lumiflavin | Others |
Lumiflavine (Lumilactoflavin) inhibits riboflavin uptake. It is produced by the photolysis of vitamin B2. | |||
T22508 | 3-CPMT | Chlortropbenzyl hydrochloride,3-[(4-chlorophenyl)-phenylmethoxy]-8-methyl-8-azabicyclo[3.2.1]octane hydrochloride,SL6057,Wy 2149,FC-1 | Dopamine Receptor |
3-CPMT (FC-1) is a dopamine uptake inhibitor and a potent long-acting antihistaminic agent. | |||
T6437 | Cefoperazone | Cefob,Medocef | Antibacterial , Antibiotic |
Cefoperazone (Medocef) binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial ce... | |||
T7591 | Coluracetam | MKC-231 | AChR , iGluR |
Coluracetam (MKC-231)(MKC-231) is a Choline Uptake Enhancer. | |||
T25276 | Crilvastatin | PMD387,PMD 387,PMD-387 | HMG-CoA Reductase |
Crilvastatin (PMD 387) is a novel non-competitive hydroxymethylglutaryl coenzyme A reductase inhibitor with cholesterol-lowering activity that inhibits cholesterol uptake in rats with hereditary hypercholesterolemia. | |||
T3142 | Drostanolone Propionate | Others | |
Dromostanolone propionate (Drostanolone propionate) is a compound that has antitumor activity against breast carcinoma [1]. Dromostanolone propionate inhibits the uptake of oestradiol-17 by the tumor without apparent eff... | |||
T7070 | Nomifensine maleate | Nomifensine (maleate),(±)-Nomifensine maleat | Dopamine Receptor |
Nomifensine maleate (Nomifensine (maleate)) is a selective inhibitor of dopamine uptake. Nomifensine maleate is used in adult attention deficit disorder. | |||
T36665 | Dehydro Nifedipine | BAY-b 4759 | |
Dehydro Nifedipine (BAY-b 4759) is the main metabolite of nifedipine in human plasma. Dehydro Nifedipine inhibits glucose uptake in PC-12 cells with an IC50 value of 130 μM. Nifedipine is a calcium channel blocker used i... | |||
T7341 | Diclofensine | Ro 8-4650 | Dopamine Receptor , Monoamine Transporter |
Diclofensine (Ro 8-4650) inhibits the uptake of serotonin, noradrenaline and dopamine. | |||
T8708 | Paroxetine | Serotonin Transporter | |
Paroxetine is a inhibitor of serotonin uptake that is effective in the treatment of depression. | |||
T24540 | NO-711ME | NO711ME,NO711 Methyl ester,N-O711 Methyl ester,N O711 Methyl ester | GABA Receptor |
NO-711ME (N-O711 Methyl ester) is a prodrug of NO-711. It also is a potent and selective GABA uptake inhibitor. | |||
T67851 | Rac Desmethyl Citalopram Hydrochloride | 5-HT Receptor | |
rac Desmethyl Citalopram Hydrochloride is a 5-hydroxy tryptamine uptake inhibitor with IC50 value of 0.013 μM. | |||
T33272 | Mefenidil | McN-2378,McN 2378 | Others |
Mefenidil (McN-2378), a selective cerebral vasodilator, was shown to increase CBF in healthy brains without stimulating O2 uptake in a dog anesthesia model. | |||
T27460 | GSK2324 | GSK-2324,GSK 2324 | FXR |
GSK2324 is a potent FXR agonist for the treatment of NAFLD by controlling hepatic lipids through reduced uptake and selective reduction of fatty acid synthesis. | |||
T26363L | Napitane | A75200,A-75200,A 75200,ABT 200 | Adrenergic Receptor |
napitane (A 75200) is a novel catecholamine uptake inhibitor with inhibitory effects on α-adrenergic receptors and potential antidepressant activity for the study of depression. | |||
T1636 | Paroxetine hydrochloride | Paroxetine HCl,BRL29060 hydrochloride,FG-7051,BRL29060A | 5-HT Receptor , Serotonin Transporter , GRK , AChR , Autophagy |
Paroxetine hydrochloride (Paroxetine HCl) is a serotonin uptake inhibitor that is effective in the treatment of depression. | |||
T1430 | Betamipron | CS-443,N-Benzoyl-β-alanine | Antibacterial , Antibiotic |
Betamipron (CS-443) is used combination with panipenem to prevent nephrotoxicity and inhibit panipenem uptake into the renal tubule. | |||
T0719 | Tetrabenazine | Xenazine,Ro 1-9569 | Others , Dopamine Receptor , Monoamine Transporter |
Tetrabenazine (Ro 1-9569) is a drug formerly used as an antipsychotic and treatment of various movement disorders. Tetrabenazine blocks neurotransmitter uptake into adrenergic storage vesicles and has been used as a high... | |||
T37015 | Iprindole | 5-HT Receptor | |
Iprindole, a tricyclic indole antidepressant, is a dual weak inhibitor of noradrenaline and 5-HT uptake [1]. | |||
T67893 | PTP1B-IN-22 | Phosphatase | |
PTP1B-IN-22 is a protein tyrosine phosphatase 1B (PTP1B) inhibitor that inhibits glucose uptake in skeletal muscle L6 myotubes. | |||
T19337 | GBR 12783 dihydrochloride | GBR12783 2HCl | Others |
GBR 12783 dihydrochloride (GBR12783 2HCl) is a specific, potent and selective dopamine uptake inhibitor. GBR 12783 dihydrochloride inhibits the [3H]dopamine uptake by rat and mice striatal synaptosomes with IC50s of 1.8 ... | |||
T8140 | Tianeptine | S-1574,JNJ-39823277,Tianeptine sodium,TPI-1062 | 5-HT Receptor |
Tianeptine (Tianeptine sodium) is a selective 5-HT uptake facilitator in vitro and in vivo. | |||
T0450L | Fluoxetine hydrochloride | Fluoxetine HCl,LY-110140,Lilly110140 | 5-HT Receptor , Serotonin Transporter , Autophagy |
Fluoxetine hydrochloride (Lilly110140) is the first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants. | |||
T14017 | 2-NBDG | Others | |
2-NBDG is a fluorescent indicator for direct glucose uptake measurement. It is an indicator of cell viability. | |||
T5327 | Amezinium methylsulfate | Amezinium metilsulfate,Amezinium (methylsulfate),Lu-1631 | Adrenergic Receptor |
Amezinium methylsulfate (Lu-1631) has multiple mechanisms, including stimulation of alpha and beta-1 receptors and inhibition of noradrenaline and tyramine uptake. | |||
T0482 | Sertraline hydrochloride | Sertraline HCl,CP-51974-1 HCl | 5-HT Receptor , Serotonin Transporter |
Sertraline hydrochloride (Sertraline HCl) is a selective serotonin uptake inhibitor that is used in the treatment of depression. | |||
T0255 | Clomipramine hydrochloride | Clomipramine HCl,Anafranil | Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Norepinephrine , GST |
Clomipramine hydrochloride (Anafranil) is a tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demeth... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T5799 | Arecaidine hydrochloride | Others | |
Arecaidine hydrochloride may have carcinogenesis. | |||
T19931 | Gentisein | NSC 329491,NSC329491,NSC-329491 | Serotonin Transporter |
Gentisein (NSC-329491), a primary metabolite of Mangiferin, exhibits significant inhibition of serotonin uptake, demonstrating potency with an IC50 value of 4.7 µM[1][2]. | |||
TL0006 | Cichoric Acid | Dicaffeoyltartaric acid,Chicoric Acid | Reactive Oxygen Species , HIV Protease |
Cichoric Acid (Dicaffeoyltartaric acid) is a potent inhibitor of human immunodeficiency virus type-1 (HIV-1) integrase and the replication in tissues. It also a class of cannabinomimetics with CB2 receptor-dependent and ... | |||
T9352 | Hydrocotarnine | Others | |
hydrocotarnine is an inhibitor of Cbl. | |||
TJS0123 | Guvacine ethyl ester | PT00442-2 | Others |
Guvacine ethyl ester (Arecoline) is an alkaloid found in betel nut that is used in the synthesis of GABA uptake inhibitors. | |||
T7557 | Guvacine hydrochloride | GABA Receptor | |
Guvacine hydrochloride is an inhibits of GABA uptake (IC50 : 10 μM) | |||
TQ0161 | Mulberrin | Kuwanon C | Others |
Mulberrin (Kuwanon C) is an inhibitor of OATP2B1-mediated estrone-3-sulfate (E3S) uptake (IC50: 1.8 ±1.5 μM). | |||
T8771 | Pongamol | Others | |
Pongamol, an identified lead molecule from the fruits of Pongamia pinnata, on glucose uptake and GLUT4 translocation in skeletal muscle cells. | |||
T0185 | Escitalopram | Seroplex,S-(+)-Citalopram,(S)-Citalopram | Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Adrenergic Receptor , AChR , Norepinephrine , Histamine Receptor |
Escitalopram (Seroplex) is a furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patien... | |||
T4959 | DL-Mannitol | Mannitol | Others |
DL-Mannitol is a osmotic diuretic, it may play a role in reducing off-target 68Ga-PSMA renal uptake | |||
TMA1122 | N-Feruloylserotonin | (E/Z)-Moschamine,Moschamine | Antioxidant |
N-Feruloylserotonin ((E/Z)-Moschamine) is a selective FAAH inhibitor that inhibits [H]-AEA uptake and cell proliferation at low concentrations. | |||
TN2285 | DL-Tryptophan | (±)-Tryptophan,Tryptophan | Serotonin Transporter , Endogenous Metabolite |
DL-Tryptophan ((±)-Tryptophan) containing dipeptides are interesting ingredients for functional foods as a natural prevention for hypertension with reduced side effects due to its selective inhibition of the C-domain. Lo... | |||
T5690 | 7,4'-Di-O-methylapigenin | 4',7-DIMETHOXY-5-HYDROXYFLAVONE | Amylase |
7,4'-Di-O-methylapigenin (4',7-DIMETHOXY-5-HYDROXYFLAVONE) can inhibit α-glucosidase and α-amylase enzymes and enhance 2-NBDG uptake in L6 cells, it has hypolipidemic effect on mouse pre-adipocyte (3T3L1) cell lines. | |||
T1045 | Trimipramine maleate | Surmontil maleate | Dopamine Receptor , 5-HT Receptor , Antibacterial , Adrenergic Receptor , Norepinephrine , Histamine Receptor |
Trimipramine maleate (Surmontil maleate) appears to inhibit serotonin transport and norepinephrine uptake by nerve terminals. This increases available norepinephrine or serotonin and prolongs its action. Trimipramine Mal... | |||
T4912 | Jatrorrhizine chloride | Yatrorhizine chloride,Neprotine chloride | Others , 5-HT Receptor , OCT , Antibacterial , AChE |
Jatrorrhizine chloride (Neprotine chloride) is a potent and orally active uptake-2 transporter inhibitor. It exhibits a critical neuroprotective role in H2O2-induced apoptosis via inhibition of the MAPK pathway in HT22 h... | |||
TN1740 | Homoeriodictyol | 5-HT Receptor , transporter , Sodium Channel , Drug Metabolite | |
Homoeriodictyol, a naturally occurring, bitter-masking flavanone, as a promising agent to increase appetite and food intake. The flavanone homoeriodictyol can increase SGLT-1-mediated glucose uptake but decrease serotoni... | |||
T3095 | Tyramine | 4-hydroxyphenethylamine,para-tyramine,p-Tyramine,mydrial,Tocosine,Uteramine | MAO , Endogenous Metabolite |
Tyramine (Uteramine) is an indirect sympathomimetic that occurs naturally in cheese and other foods. Tyramine does not directly activate adrenergic receptors, but it can serve as a substrate for adrenergic uptake systems... | |||
T5061 | Lumichrome | 7,8-Dimethylalloxazine | Others |
Lumichrome (7,8-Dimethylalloxazine) is a natural metabolite of riboflavin. Lumichrome produced by Rhizobium and other bacterial species induces major developmental changes in plants at nanomolar concentrations. Lumichrom... | |||
T2S0265 | Robinin | NSC 9222 | TLR |
Flavone glycoside from Robinia with antibacterial and diuretic properties; derived from kaempferol.The ability of robinin to reverse the multidrug resistance of the human colon cancer cell line Colo 320 expreβing MDR1/LR... | |||
T4S0779 | D-tetrahydropalmatine | Others , Dopamine Receptor | |
D-Tetrahydropalmatine is a organic cation transporter 1 (OCT1) inhibitor, it can obviously inhibit the uptake of monocrotaline (MCT) in MDCK-hOCT1 cells and isolate rat primary hepatocytes, and attenuate the viability re... | |||
T6S0232 | Eriodictyol | Huazhongilexone | Influenza Virus , DNA/RNA Synthesis , Nrf2 , Endogenous Metabolite |
1. Eriodictyol (Huazhongilexone) is a flavonoid with anti-inflammatory and antioxidant activities. 2. Eriodictyol may possess antidiabetic properties through increasing glucose uptake and improving insulin resistance. 3.... | |||
TN2111 | Prunin | Naringenin 7-0-glucoside | Phosphatase , Anti-infection , Virus Protease |
Prunin (Naringenin 7-0-glucoside) possesses anti-diabetic, and anti-abacterial properties, it can inhibit protein tyrosine phosphatase 1B (PTP1B) and stimulate glucose uptake in insulin-resistant HepG2 cells; it also can... | |||
T0791 | Reserpine | Serpalan,Serpasil,Serpivite | Others , Potassium Channel , MRP , Monoamine Transporter , Autophagy |
Reserpine (Serpalan) is an alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotoni... | |||
T2P2923 | Stearic acid | Isostearic acid,Octadecanoic acid,Cetylacetic acid | Phosphatase , Endogenous Metabolite |
1. Stearic acid (Cetylacetic acid) can reduce metastatic tumor burden. 2. Stearic acid leads to dramatically reduced visceral fat likely by causing the apoptosis of preadipocytes. 3. Stearic acid and its derivatives have... | |||
T5S1172 | Tiliroside | Tribuloside | Antioxidant |
1. Tiliroside (Tribuloside) shows anticarcinogenic activity. 2. Tiliroside shows hepatoprotective activity. 3. Tiliroside shows antioxidant and anti-inflammatory activity, can inhibit neuroinflammation in neurodegenerati... | |||
T1311 | 4-aminobenzoic acid | PABA,Vitamin H1,Vitamin Bx,para-Aminobenzoic acid | Endogenous Metabolite |
4-aminobenzoic acid (para-Aminobenzoic acid) is an organic acid with UV absorption and antifibrotic properties. When exposed to light, 4-aminobenzoic acid absorbs UV light and emits excess energy via a photochemical reac... | |||
T4962 | Zingibroside R1 | Ginsenoside Z-R1 | HIV Protease |
Zingibroside R1 (Ginsenoside Z-R1) has anti-HIV-1 activity. | |||
T3933 | Jatrorrhizine | Yatrorizine,neprotin | MAO , 5-HT Receptor , Antibacterial , AChE |
Jatrorrhizine (neprotin) is a protoberberine alkaloid isolated from Enantia chlorantha (Annonaceae) and other species. It was found to have antimicrobial and antifungal activity. It binds and noncompetitively inhibits mo... | |||
T25533 | Indalpine | LM-5008,Lipstene,Indalpino,LM 5008,LM5008 | |
Indalpine is used as a selective 5-hydroxytryptamine uptake inhibitor. | |||
T39613 | 11-epi-mogroside V | ||
11-epi-mogroside V, a compound found in the fruit of Siraitia grosvenori, possesses significant bioactivity by enhancing glucose uptake in vitro, specifically in human HepG2 cells. | |||
T80013 | Arecaidine hydrobromide | GABA Receptor | |
Arecaidine hydrobromide, a pyridine alkaloid, functions as a potent GABA uptake inhibitor and acts as a substrate for the H+-coupled amino acid transporter 1 (PAT1, SLC36A1), where it competitively inhibits L-proline upt... | |||
TN4822 | Prehelminthosporol | Antifection | |
Prehelminthosporol is a phytotoxin, it may play an important role in pathogenesis by killing or weakening plant cells in advance of the growing hyphae and facilitating nutrient uptake and further growth of the fungus in ... | |||
TN4905 | Rehmannic acid | NADPH-oxidase | |
Rehmannic acid and oleanolic acetate inhibit succinoxidase activity. Both Rehmannic acid and Icterogenin are potent uncouplers, abolishing the phosphate uptake, the respiration being inhibited by the former and increased... | |||
TN1368 | Alisol C | Others | |
Alisol C can improve glucose uptake in Hep G2 cells, it may be one of the therapeutic material basis in hypoglycemic activities in A. orientalis. Alisol C,16,23-oxido-alisol B and alisol O in Zexie may cause nephrotoxici... | |||
T3S0964 | Thermopsoside | Chrysoeriol-7-O-glucoside | Others |
Chrysoeriol-7-O-glucoside can strongly inhibit the classical pathway of the complement system.Chrysoeriol-7-O-d-glucoside and luteolin-7-O-d-glucoside can inhibit palmitic acid uptake into small intestinal brush border m... | |||
TN1462 | Cajanin | ERK , MEK , Akt | |
Cajanin has potential hypolipidemic effects,possibly via up-regulating the ABCA1 protein expression,subsequently resulting in increased macrophage cholesterol efflux and RCT, it can significantly improve basal glucose up... | |||
TN4944 | Santamarine | Caspase | |
Santamarine has significant anticancer activity, can inhibit L1210 cells because of its cytotoxic,cytostatic and blocking mitosis and reducing uptake of thymidine. Santamarine and reynosin show bactericidal activity agai... | |||
T37232 | (+)-Geodin | ||
(+)-Geodin is a fungal metabolite. It increases the fibrinolytic activity of bovine aortic endothelial cells (BAECs) when used at concentrations ranging from 50 to 150 μM. (+)-Geodin (1-100 μg/ml) also increases 2-deoxyg... | |||
T75436 | Jatrorrhizine hydroxide | ||
Jatrorrhizine hydroxide, an alkaloid derived from Coptis chinensis, exhibits a range of biological activities including neuroprotective, antimicrobial, antiplasmodial, and antioxidant properties [1]. It acts as a potent ... | |||
TN4691 | Octadecyl caffeate | Others | |
z-Octadecyl caffeate may have pain-relieving activity. Octadecyl caffeate and coptisonine can stimulate glucose uptake at 25 and 50 ug/mL. Octadecyl caffeate and octadecyl coumarate applied to the surface of susceptible ... | |||
T80014 | Guvacine hydrobromide | GABA Receptor | |
Guvacine hydrobromide, an alkaloid derived from the Areca catechu nut, serves as a potent inhibitor of GABA (GABA uptakp) uptake. It effectively inhibits rat GABA transporter isoforms GAT-1, GAT-2, and GAT-3, with respec... | |||
T38394 | PSMα3 | ||
PSMα3 is a peptide compound that can be utilized to induce tolerance in dendritic cells (DCs) for DC vaccination strategies. It effectively penetrates and modulates human monocyte-derived DCs by modifying the maturation ... | |||
TN4997 | Serpentine | IGF-1R | |
Serpentine is an alkaloid found in the roots of Rosa Centifolia that acts as an insulin sensitizer to assist insulin in lowering blood glucose.Serpentine activates the phosphorylation of AMPK, which stimulates glucose up... | |||
T37911 | Cis-Resveratrol | (Z)-Resveratrol | |
Resveratrol is a potent phenolic antioxidant found in grapes, red wine, and various berries that also has antiproliferative and anti-inflammatory activity. cis-Resveratrol is the double bond isomer of trans-resveratrol, ... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPJ-00059 | IL-7 Protein, Human, Recombinant (His) | Human | Human Cells |
Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions... | |||
TMPY-02907 | FGF-19 Protein, Human, Recombinant | Human | E. coli |
FGF19, also known as FGF-19, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, inclu... | |||
TMPY-00395 | Insulin Protein, Human, Recombinant | Human | Yeast |
INS (Insulin) is a Protein Coding gene. This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsul... | |||
TMPY-04878 | IGF1/IGF-I Protein, Mouse, Recombinant | Mouse | Yeast |
IGF I, also known as Mechano Growth Factor, somatomedin-C, IGF-I, and IGF1, is a secreted protein that belongs to the insulin family. The insulin family, comprised of insulin, relaxin, insulin-like growth factors I and I... | |||
TMPY-01280 | FOLR2 Protein, Human, Recombinant (His) | Human | HEK293 |
Folate receptor beta, also known as Folate receptor 2, FBP, and FOLR2, is a member of the folate receptor family. FOLR2 is expressed in placenta and hematopoietic cells. The expression of FOLR2 is increased in malignant ... | |||
TMPY-01081 | SR-BI/SCARB1 Protein, Human, Recombinant (His) | Human | HEK293 |
Scavenger receptor class B, member 1 (SCARB1), also known as CD36L1, is a member of the scavenger receptor family. SCARB1 is expressed primarily in liver and non placental steroidogenic tissues, and predominantly localiz... | |||
TMPY-01815 | FOLR1 Protein, Human, Recombinant (His) | Human | HEK293 |
The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product i... | |||
TMPY-06022 | FOLR1 Protein, Cynomolgus, Rhesus, Recombinant (His) | Cynomolgus,Rhesus | HEK293 |
The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product i... | |||
TMPY-06982 | IGF1/IGF-I Protein, Human, Recombinant | Human | E. coli |
IGF I, also known as Mechano Growth Factor, somatomedin-C, IGF-I, and IGF1, is a secreted protein that belongs to the insulin family. The insulin family, comprised of insulin, relaxin, insulin-like growth factors I and I... | |||
TMPY-00432 | TREM-2 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Triggering receptor expressed on myeloid cells 2 ( TREM2 ) is a single Ig domain receptor. It is expressed on macrophages and dendritic cells but not on granulocytes or monocytes. Its expression is most abundant in the b... | |||
TMPY-01148 | TREM-2 Protein, Human, Recombinant (His) | Human | HEK293 |
Triggering receptor expressed on myeloid cells 2 ( TREM2 ) is a single Ig domain receptor. It is expressed on macrophages and dendritic cells but not on granulocytes or monocytes. Its expression is most abundant in the b... | |||
TMPY-00835 | IGFBP-3 Protein, Human, Recombinant (His) | Human | HEK293 |
The Insulin-like Growth Factor (IGF) signaling system plays a central role in cellular growth, differentiation, and proliferation. IGFBP3 is the most abundant IGF binding protein in human serum and is a growth inhibitory... | |||
TMPY-01803 | FOLR1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product i... | |||
TMPY-01703 | TREM-2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Triggering receptor expressed on myeloid cells 2 ( TREM2 ) is a single Ig domain receptor. It is expressed on macrophages and dendritic cells but not on granulocytes or monocytes. Its expression is most abundant in the b... | |||
TMPY-00915 | Serpin A1 Protein, Human, Recombinant (His) | Human | HEK293 |
SerpinA1, also known as Alpha-1 antitrypsin (AAT), is a prototype member of the Serpin superfamily of the serine protease inhibitors. This serine protease inhibitor blocks the protease, neutrophil elastase. Alpha-1 antit... | |||
TMPY-01279 | Transferrin Protein, Human, Recombinant (His) | Human | HEK293 |
Transferrin is a glycoprotein with an approximate molecular weight of 76.5 kDa. This glycoprotein is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C an... | |||
TMPY-05337 | CXCL16 Protein, Human, Recombinant (His) | Human | HEK293 |
C-X-C motif chemokine 16, also known as Small-inducible cytokine B16, SR-PSOX, and CXCL16, is a single-pass type I membrane protein which belongs to the intercrine alpha (chemokine CxC) family. CXCL16 exists in transmemb... | |||
TMPY-03295 | Transferrin Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Transferrin is a glycoprotein with an approximate molecular weight of 76.5 kDa. This glycoprotein is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C an... | |||
TMPH-02496 | Adipolin Protein, Mouse, Recombinant (E. coli, His) | Mouse | E. coli |
Insulin-sensitizing adipocyte-secreted protein (adipokine) that regulates glucose metabolism in liver and adipose tissue. Promotes glucose uptake in adipocytes and suppresses de novo glucose production in hepatocytes via... | |||
TMPH-02333 | SLC25A19 Protein, Human, Recombinant (His) | Human | in vitro E. coli expression system |
Mitochondrial transporter mediating uptake of thiamine pyrophosphate (ThPP) into mitochondria. | |||
TMPH-02646 | Erythroferrone Protein, Mouse, Recombinant (His) | Mouse | Yeast |
Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increase... | |||
TMPH-02124 | SLC23A2 Protein, Human, Recombinant (His) | Human | in vitro E. coli expression system |
Sodium/ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate. | |||
TMPH-00298 | Resistin Protein, Bovine, Recombinant (His) | Bovine | E. coli |
Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. Potentially links obesity to diabetes. | |||
TMPH-02120 | SLC5A5 Protein, Human, Recombinant (His) | Human | E. coli |
Mediates iodide uptake in the thyroid gland. | |||
TMPH-01540 | Intelectin-1/ITLN1 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Lectin that specifically recognizes microbial carbohydrate chains in a calcium-dependent manner. Binds to microbial glycans that contain a terminal acyclic 1,2-diol moiety, including beta-linked D-galactofuranose (beta-G... | |||
TMPH-02497 | Adipolin Protein, Mouse, Recombinant (His) | Mouse | Baculovirus |
Insulin-sensitizing adipocyte-secreted protein (adipokine) that regulates glucose metabolism in liver and adipose tissue. Promotes glucose uptake in adipocytes and suppresses de novo glucose production in hepatocytes via... | |||
TMPH-01612 | LSR Protein, Human, Recombinant (His) | Human | E. coli |
Probable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells. | |||
TMPH-01301 | Erythroferrone Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increase... | |||
TMPH-01616 | LRP2 Protein, Human, Recombinant (mFc) | Human | HEK293 |
Multiligand endocytic receptor. Acts together with CUBN to mediate endocytosis of high-density lipoproteins. Mediates receptor-mediated uptake of polybasic drugs such as aprotinin, aminoglycosides and polymyxin B. In the... | |||
TMPH-03231 | AFP2 Protein, Raphanus sativus, Recombinant (His & SUMO) | Raphanus sativus | E. coli |
Possesses antifungal activity sensitive to inorganic cations. Induces potential changes in fungal membranes and increased K(+) efflux and Ca(2+) uptake. | |||
TMPH-01381 | GDNF Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. | |||
TMPH-02600 | C1QL3 Protein, Mouse, Recombinant (His & Myc) | Mouse | Baculovirus |
May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses. Plays a role in glucose homeostasis. Via AMPK signaling pathway, stimulates glucose uptake in a... | |||
TMPH-00628 | GltI/YbeJ Protein, E. coli, Recombinant (His & SUMO) | E. coli | E. coli |
Part of the ABC transporter complex GltIJKL involved in glutamate and aspartate uptake. Binds to both glutamate and aspartate. | |||
TMPH-02122 | SLC2A1 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. Most imp... | |||
TMPH-02897 | SPINK1 Protein, Mouse, Recombinant (His) | Mouse | Yeast |
Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin-catalyzed premature activation of zymogens.; In the male reproductive tract, binds to sperm heads where it modulat... | |||
TMPH-02808 | NPTX1 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses. | |||
TMPH-02807 | NPTXR Protein, Mouse, Recombinant (His & Myc) | Mouse | Baculovirus |
May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses. | |||
TMPH-01604 | SLC7A5 Protein, Human, Recombinant (His & Myc & SUMO) | Human | E. coli |
The heterodimer with SLC3A2 functions as sodium-independent, high-affinity transporter that mediates uptake of large neutral amino acids such as phenylalanine, tyrosine, L-DOPA, leucine, histidine, methionine and tryptop... | |||
TMPH-02824 | Perforin-1/PRF1 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large po... | |||
TMPH-00039 | Single-strand DNA-binding protein Protein, Agrobacterium fabrum, Recombinant (His & Myc) | Agrobacterium fabrum | E. coli |
Involved in DNA transformation; mediates the nuclear uptake of single-stranded DNA copies of the transferred DNA (T-DNA) element. Binds single-stranded but not double-stranded DNA regardless of nucleotide sequence compos... | |||
TMPH-02611 | Langerin/CD207 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated... | |||
TMPH-00706 | MppA Protein, E. coli, Recombinant (His & SUMO) | E. coli | E. coli |
Essential for the uptake of the murein peptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate. Also transports some alpha-linked peptides such as Pro-Phe-Lys with low affinity. The transport is effected by the oligopepti... | |||
TMPH-01577 | KRT18 Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Involved in the uptake of thrombin-antithrombin complexes by hepatic cells. When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT... | |||
TMPH-02421 | APOE Protein, Cynomolgus, Recombinant (His & Myc) | Cynomolgus | E. coli |
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plas... | |||
TMPH-01578 | KRT18 Protein, Human, Recombinant (His) | Human | HEK293 |
Involved in the uptake of thrombin-antithrombin complexes by hepatic cells. When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT... | |||
TMPJ-00533 | LYVE1 Protein, Human, Recombinant (His) | Human | Human Cells |
Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1 is a single-pass type I membrane protein. LYVE-1 is a CD44 homolog found primarily on lymphatic endothelial cells 1. LYVE-1 mainly expressed in endothelial cells li... | |||
TMPH-03199 | APOE Protein, Rabbit, Recombinant (His & Myc & SUMO) | Rabbit | E. coli |
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plas... | |||
TMPH-00284 | MBP-C Protein, Bovine, Recombinant (His) | Bovine | Baculovirus |
Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as... | |||
TMPH-03127 | GH Protein, Pig, Recombinant (His & Myc) | Sus scrofa (Pig) | E. coli |
Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It... | |||
TMPH-02447 | GH Protein, Rhesus macaque, Recombinant (His & Myc) | Rhesus | E. coli |
Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It... | |||
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カタログ番号 | 製品名 | ||
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L1120 | AMPK-Targeted Compound Library | 80 compounds | |
80 well-chosen unique AMPK-targeted small molecules; |