store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Lifirafenib (Beigene-283) is a potent inhibitor of RAF family kinases and EGFR in biochemical assays with IC50 of 23, 29 and 495 nM for the recombinant BRAFV600E kinase domain, EGFR and EGFR T790M/L858R mutant respectively.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 10,000 | |||
5 mg | 在庫あり | ¥ 24,000 | |||
10 mg | 在庫あり | ¥ 39,500 | |||
25 mg | 在庫あり | ¥ 76,500 | |||
50 mg | 在庫あり | ¥ 135,500 | |||
100 mg | 在庫あり | ¥ 211,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 35,500 |
説明 | Lifirafenib (Beigene-283) is a potent inhibitor of RAF family kinases and EGFR in biochemical assays with IC50 of 23, 29 and 495 nM for the recombinant BRAFV600E kinase domain, EGFR and EGFR T790M/L858R mutant respectively. |
ターゲット&IC50 | B-Raf (V600E):23 nM, EGFR:29 nM, EGFR (L858R/T790M):495 nM (IC50) |
別名 | BGB-283, Beigene-283 |
分子量 | 478.42 |
分子式 | C25H17F3N4O3 |
CAS No. | 1446090-79-4 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (209.02 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Lifirafenib 1446090-79-4 Angiogenesis JAK/STAT signaling MAPK Tyrosine Kinase/Adaptors EGFR Raf Epidermal growth factor receptor ErbB-1 inhibit BGB-283 Raf kinases Beigene-283 Inhibitor HER1 BGB 283 BGB283 inhibitor