Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Loreclezole is a selective GABAA receptor modulator and acts as a positive allosteric modulator of β2 or β3-subunit-containing receptors.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 9,500 | |||
5 mg | 在庫あり | ¥ 22,500 | |||
10 mg | 在庫あり | ¥ 34,000 | |||
25 mg | 在庫あり | ¥ 67,500 | |||
50 mg | 在庫あり | ¥ 131,500 | |||
100 mg | 在庫あり | ¥ 189,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 22,500 |
説明 | Loreclezole is a selective GABAA receptor modulator and acts as a positive allosteric modulator of β2 or β3-subunit-containing receptors. |
In vitro | Loreclezole, at concentrations above 6 microM, enhanced the degree and rate of apparent desensitization of the whole-cell current in a concentration-dependent manner [1]. The action of loreclezole depends on the type of beta subunit present in the receptor complex; receptors containing beta 2 or beta 3 subunits have > 300-fold higher affinity for loreclezole than receptors containing a beta 1 subunit [2]. |
分子量 | 274.53 |
分子式 | C10H6Cl3N3 |
CAS No. | 117857-45-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90 mg/mL (327.83 mM)
You can also refer to dose conversion for different animals. 詳細
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Loreclezole 117857-45-1 Membrane transporter/Ion channel Neuroscience GABA Receptor γ-Aminobutyric acid Receptor R 72063 Inhibitor Gamma-aminobutyric acid Receptor R72063 R-72063 inhibit inhibitor