Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Saclofen is a sulfonic analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) that acts as a competitive antagonist of the GABAB receptor (IC50: 7.8 μM).1 This compound can be used to determine the functional roles for the GABAB receptor as a mediator of slow inhibitory postsynaptic potentials in the brain.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 12,000 | |||
5 mg | 在庫あり | ¥ 28,000 | |||
10 mg | 在庫あり | ¥ 45,500 | |||
25 mg | 在庫あり | ¥ 104,500 | |||
50 mg | 在庫あり | ¥ 154,500 | |||
100 mg | 在庫あり | ¥ 219,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 27,000 |
説明 | Saclofen is a sulfonic analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) that acts as a competitive antagonist of the GABAB receptor (IC50: 7.8 μM).1 This compound can be used to determine the functional roles for the GABAB receptor as a mediator of slow inhibitory postsynaptic potentials in the brain. |
ターゲット&IC50 | GABAB:7.8 μM |
In vivo | CCT241736 significantly inhibited the growth of MV4-11 human FLT3-ITD positive AML tumor xenografts in vivo, with biomarker modulation and free drug exposure consistent with dual FLT3 and Aurora kinase target inhibition |
分子量 | 249.71 |
分子式 | C9H12ClNO3S |
CAS No. | 125464-42-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 5.5 mg/mL (22.03 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Saclofen 125464-42-8 Membrane transporter/Ion channel Neuroscience GABA Receptor Gamma-aminobutyric acid Receptor γ-Aminobutyric acid Receptor Inhibitor inhibit inhibitor