Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Tiagabine (NO050328) is an Anti-epileptic Agent. The physiologic effect of tiagabine is by means of Decreased Central Nervous System Disorganized Electrical Activity.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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5 mg | 在庫あり | ¥ 8,500 | |||
10 mg | 在庫あり | ¥ 11,500 | |||
50 mg | 在庫あり | お問い合わせ | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 12,000 |
説明 | Tiagabine (NO050328) is an Anti-epileptic Agent. The physiologic effect of tiagabine is by means of Decreased Central Nervous System Disorganized Electrical Activity. |
In vitro | Tiagabine is a potent inhibitor of GABA uptake into neurons and glial cells. It is involved in modulating GABA levels, especially in areas such as the hippocampus and thalamus[2]. Tiagabine not only affected the decay kinetics of the IPSCs, it also reduced the frequency of occurrence of both spontaneous and miniature IPSCs[1]. |
In vivo | Tiagabine offers a significant neuroprotection in global ischemia in gerbils when given 30 min before ischemia but not when given 3 h after ischemia[3]. |
別名 | TGB, NO050328, Gabitril, NO328 |
分子量 | 375.55 |
分子式 | C20H25NO2S2 |
CAS No. | 115103-54-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mg/mL (26.63 mM)
You can also refer to dose conversion for different animals. 詳細
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Tiagabine 115103-54-3 Membrane transporter/Ion channel Neuroscience GABA Receptor NO 050328 Gamma-aminobutyric acid Receptor TGB NO050328 Inhibitor inhibit γ-Aminobutyric acid Receptor Gabitril NO-328 NO 328 NO328 NO-050328 inhibitor