Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Loureirin A has an inhibitory effect on platelet activation, perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen, collagen-related peptide (CRP), ADP and thrombin. Loureirin A activates Wnt/-catenin pathway and promotes hair follicle stem cells (FSCs)-seeded tissue-engineered skin to repair skin wound.The molecular mechanism of Loureirin A and Wnt signaling pathway mediated anti- hepatic fibrosis and anti- angiogenesis may involve down- regulation the expression of Frizzled- 4,inhibiting the synthesis and secretion of α- SMA,TGF- β1and the proliferation of HSCs.
説明 | Loureirin A has an inhibitory effect on platelet activation, perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen, collagen-related peptide (CRP), ADP and thrombin. Loureirin A activates Wnt/-catenin pathway and promotes hair follicle stem cells (FSCs)-seeded tissue-engineered skin to repair skin wound.The molecular mechanism of Loureirin A and Wnt signaling pathway mediated anti- hepatic fibrosis and anti- angiogenesis may involve down- regulation the expression of Frizzled- 4,inhibiting the synthesis and secretion of α- SMA,TGF- β1and the proliferation of HSCs. |
植物由来 |
分子量 | 286.32 |
分子式 | C17H18O4 |
CAS No. | 119425-89-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 86.6 mg/mL (302.46 mM)
You can also refer to dose conversion for different animals. 詳細
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Loureirin A 119425-89-7 Cytoskeletal Signaling PI3K/Akt/mTOR signaling Akt PI3K PKB Protein kinase B Inhibitor inhibit inhibitor