Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Oridonin (NSC-250682) is a diterpenoid isolated from Rabdosia rubescens with anti-tumor, anti-bacterial and anti-inflammatory effects. It acts as an inhibitor of AKT, with IC50s of 8.4 and 8.9 μM for AKT1 and AKT2.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
10 mg | 在庫あり | ¥ 10,500 | |||
50 mg | 在庫あり | ¥ 20,500 | |||
100 mg | 在庫あり | ¥ 33,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 11,500 |
説明 | Oridonin (NSC-250682) is a diterpenoid isolated from Rabdosia rubescens with anti-tumor, anti-bacterial and anti-inflammatory effects. It acts as an inhibitor of AKT, with IC50s of 8.4 and 8.9 μM for AKT1 and AKT2. |
ターゲット&IC50 | Akt2:8.9 μM, Akt1:8.4μM |
In vivo | LD50: Mice 35-40 mg/kg. [4] |
植物由来 |
別名 | NSC-250682, Rubescenin, Isodonol, Rubescensin A |
分子量 | 364.44 |
分子式 | C20H28O6 |
CAS No. | 28957-04-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: < 1 mg/mL (insoluble or slightly soluble)
Ethanol: 28 mg/mL (76.83 mM)
DMSO: 72 mg/mL (197.57 mM)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Oridonin 28957-04-2 Cytoskeletal Signaling Microbiology/Virology PI3K/Akt/mTOR signaling Akt Antibacterial NSC-250682 Bacterial Rubescenin Inhibitor Isodonol NSC 250682 NSC250682 inhibit Protein kinase B PKB Rubescensin A inhibitor