Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ML380 is a highly potent and the first CNS penetrant M5 positive allosteric modulator (PAM).
説明 | ML380 is a highly potent and the first CNS penetrant M5 positive allosteric modulator (PAM). |
ターゲット&IC50 | M5 mAChR (human):190 nM, M5 mAChR (rat):610 nM |
別名 | ML 380, ML-380 |
分子量 | 494.53 |
分子式 | C23H25F3N4O3S |
CAS No. | 1627138-52-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90 mg/mL (181.99 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
ML380 1627138-52-6 Neuroscience AChR positive ML 380 Muscarinic acetylcholine receptor allosteric inhibit ACh ML-380 modulator Inhibitor mAChR PAM inhibitor