Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Mc-MMAE (Maleimidocaproyl-monomethylauristatin E) is a drug-linker conjugate for ADC. Mc-MMAE is a maleimidocaproyl-conjugated monomethyl auristatin E, which is a potent tubulin inhibitor.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 50,500 |
5 mg | 在庫あり | ¥ 100,500 |
10 mg | 在庫あり | ¥ 157,500 |
25 mg | 在庫あり | ¥ 245,500 |
50 mg | 在庫あり | ¥ 333,000 |
100 mg | 在庫あり | ¥ 447,500 |
説明 | Mc-MMAE (Maleimidocaproyl-monomethylauristatin E) is a drug-linker conjugate for ADC. Mc-MMAE is a maleimidocaproyl-conjugated monomethyl auristatin E, which is a potent tubulin inhibitor. |
In vitro | The production of maleimidocaproyl-MMAE (mc-MMAE) involves introducing maleimidocaproic acid into a dichloromethane solution containing MMAE. This process is then followed by adding diethyl cyanophosphonate and diisopropylethylamine[1]. |
別名 | Maleimidocaproyl-monomethylauristatin E |
分子量 | 911.18 |
分子式 | C49H78N6O10 |
CAS No. | 863971-24-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 51 mg/mL (55.97 mM)
H2O: < 0.1 mg/mL (insoluble), Sonication and heating to 60℃ are recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Mc-MMAE 863971-24-8 Cytoskeletal Signaling Microtubule Associated Inhibitor Drug-Linker Conjugates for ADC McMMAE Microtubule/Tubulin Mc MMAE inhibit Maleimidocaproyl-monomethylauristatin E inhibitor