Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Suprafenacine (N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide) is a cell-permeable microtubule destabilizer that induces cell cycle arrest and apoptosis in G2/M phase. Suprafenacine binds to microtubules and inhibits aggregation at the colchicine junction. Suprafenacine is selective for cancer cells, including drug-resistant cancer cells.
説明 | Suprafenacine (N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide) is a cell-permeable microtubule destabilizer that induces cell cycle arrest and apoptosis in G2/M phase. Suprafenacine binds to microtubules and inhibits aggregation at the colchicine junction. Suprafenacine is selective for cancer cells, including drug-resistant cancer cells. |
別名 | N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide |
分子量 | 282.34 |
分子式 | C16H18N4O |
CAS No. | 1477482-50-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 8 mg/ml(28.33 mM)
You can also refer to dose conversion for different animals. 詳細
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Suprafenacine 1477482-50-0 Cytoskeletal Signaling Microtubule Associated N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide Inhibitor inhibitor inhibit