Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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50 mg | 在庫あり | ¥ 9,500 | |||
100 mg | 在庫あり | ¥ 11,000 | |||
200 mg | 在庫あり | ¥ 13,500 | |||
500 mg | 在庫あり | ¥ 18,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 11,500 |
説明 | Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations. |
In vitro | In sheep lambs administered Albendazole intravenously, the drug and its active metabolite, albendazole sulfoxide, are recovered in tapeworms. In rats, Albendazole significantly increases hepatic activity: it induces a 65-fold increase in CYP1A1-related ethoxyresorufin O-deethylase (EROD) activity, a 6-fold increase in CYP1A2-related methoxyresorufin O-demethylase activity, a 4-fold increase in CYP2B1-related pentoxyresorufin O-dealkylase activity, a 14-fold increase in CYP2B2-related benzyloxyresorufin O-dealkylase activity, and also leads to a partial reduction in CYP2E1-related p-nitrophenol hydroxylase activity. Albendazole is metabolized by liver and lung microsomes in sheep and cattle as well as bovine intestinal microsomes into its pharmacologically active sulfoxide metabolite. |
In vivo | Albendazole and its sulfoxide metabolites induce the accumulation of cells in the mitotic phase. |
別名 | SKF-62979 |
分子量 | 265.33 |
分子式 | C12H15N3O2S |
CAS No. | 54965-21-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 14 mg/mL (52.8 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Albendazole 54965-21-8 Chromatin/Epigenetic Cytoskeletal Signaling Metabolism Microbiology/Virology Parasite Antibiotic Microtubule Associated HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species Inhibitor LC3 Echinococcus granulosus caspase-3 Hypoxia-inducible factors VEGFR Autophagy inhibit PARP tapeworm HIFs Microtubule/Tubulin VEGF SKF 62979 SKF62979 parasiticide Apoptosis HIF-PH SKF-62979 Vascular endothelial growth factor receptor inhibitor