keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
N-Caffeoyltryptophan (trans-Caffeoyl-L-tryptophan), a potential Sirt inhibitor, is screened using coffee extract. N-Caffeoyltryptophan inhibited Sirt2 (IC50; 8.7 μM) better than Sirt1(IC50; 34μM).
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 24,500 | |||
2 mg | 在庫あり | ¥ 34,000 | |||
5 mg | 在庫あり | ¥ 55,000 | |||
10 mg | 在庫あり | ¥ 81,500 | |||
25 mg | 在庫あり | ¥ 135,000 | |||
50 mg | 在庫あり | ¥ 192,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 59,500 |
説明 | N-Caffeoyltryptophan (trans-Caffeoyl-L-tryptophan), a potential Sirt inhibitor, is screened using coffee extract. N-Caffeoyltryptophan inhibited Sirt2 (IC50; 8.7 μM) better than Sirt1(IC50; 34μM). |
ターゲット&IC50 | SIRT1:34μM, SIRT2:8.7 μM |
In vitro | In cellular levels,N-Caffeoyltryptophan was able to increase the acetylation of total lysine, cortactin and histone H3 in neuronal NG108-15 cells. In the same cells, the amide also increased the acetylation of lysine (K382) in p53, but not (K305)[1]. |
別名 | trans-Caffeoyl-L-tryptophan |
分子量 | 366.37 |
分子式 | C20H18N2O5 |
CAS No. | 109163-69-1 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (122.83 mM)
You can also refer to dose conversion for different animals. 詳細
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N-Caffeoyltryptophan 109163-69-1 Chromatin/Epigenetic DNA Damage/DNA Repair Sirtuin trans-Caffeoyl-L-tryptophan N Caffeoyltryptophan NCaffeoyltryptophan Inhibitor inhibitor inhibit