Powder: -20°C for 3 years | In solvent: -80°C for 1 year
N-piperidine Ibrutinib is a potent BTK inhibitor with IC50s of 51.0 for WT BTK and 30.7 nM for C481S BTK respectively. N-piperidine Ibrutinib can be used as a BTK ligand in the synthesis of a series of PROTACs, such as SJF620. SJF620 is a potent PROTAC BTK degrader with a DC50 of 7.9 nM.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 34,000 | |||
5 mg | 在庫あり | ¥ 77,500 | |||
10 mg | 在庫あり | ¥ 113,500 | |||
25 mg | 在庫あり | ¥ 181,500 | |||
50 mg | 在庫あり | ¥ 257,000 | |||
100 mg | 在庫あり | ¥ 342,000 |
説明 | N-piperidine Ibrutinib is a potent BTK inhibitor with IC50s of 51.0 for WT BTK and 30.7 nM for C481S BTK respectively. N-piperidine Ibrutinib can be used as a BTK ligand in the synthesis of a series of PROTACs, such as SJF620. SJF620 is a potent PROTAC BTK degrader with a DC50 of 7.9 nM. |
In vitro | N-piperidine Ibrutinib can be used as a BTK ligand in the synthesis of a series of PROTACs. SJF638, SJF678, and SJF608 are potent PROTAC BTK degraders with DC50s of 374, 162, and 8.3 nM, respectively[2]. |
分子量 | 386.45 |
分子式 | C22H22N6O |
CAS No. | 330785-90-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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N-piperidine Ibrutinib 330785-90-5 Angiogenesis Tyrosine Kinase/Adaptors BTK N piperidine Ibrutinib Npiperidine Ibrutinib Inhibitor inhibitor inhibit