Powder: -20°C for 3 years | In solvent: -80°C for 1 year
NS-3-008 hydrochloride (NS-3-008 HCl) is a transcriptional G0/G1 switch 2 (G0s2) inhibitor( IC50 of 2.25 μM).
説明 | NS-3-008 hydrochloride (NS-3-008 HCl) is a transcriptional G0/G1 switch 2 (G0s2) inhibitor( IC50 of 2.25 μM). |
ターゲット&IC50 | G0s2:2.25 μM |
In vivo | Administration of NS-3-008 inhibited the expression of G0s2 in healthy mice liver.?In contrast, administration of NS-3-008 did not affect the MBP in wild-type sham and 5/6Nx mice.?NS-3-008 as a novel G0s2 inhibitor and showed that administration of this inhibitor ameliorated renal dysfunction in wild-type 5/6Nx mice. |
別名 | NS-3-008 HCl |
分子量 | 269.81 |
分子式 | C14H24ClN3 |
CAS No. | 1172854-54-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 120 mg/mL(444.76 mM), Sonication is recommended.
H2O: 125 mg/mL (463.29 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
NS-3-008 hydrochloride 1172854-54-4 Others renal inhibit Ccl2 NS3008 hydrochloride Hsd17b4 Stat5 transcriptional Inhibitor NS-3-008 Hydrochloride dysfunction ameliorate CKD NS 3 008 hydrochloride p65 NS-3-008 HCl G0s2 inhibitor