Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Nexopamil (LU-49938) is a calcium channel antagonist and a 5-hydroxytryptamine 2A receptor antagonist. Nexopamil inhibits 5-HT-induced contraction and proliferation of mesenchymal cells.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 27,500 | |||
5 mg | 在庫あり | ¥ 66,500 | |||
10 mg | 在庫あり | ¥ 101,000 | |||
25 mg | 在庫あり | ¥ 167,000 | |||
50 mg | 在庫あり | ¥ 226,500 | |||
100 mg | 在庫あり | ¥ 319,000 | |||
500 mg | 在庫あり | ¥ 636,000 |
説明 | Nexopamil (LU-49938) is a calcium channel antagonist and a 5-hydroxytryptamine 2A receptor antagonist. Nexopamil inhibits 5-HT-induced contraction and proliferation of mesenchymal cells. |
In vitro | Nexopamil abolished in a concentration-dependent way the serotonin-induced [3H]thymidine incorporation into DNA, and the serotonin-induced increase in a number of cells. Nexopamil partially blocked the serotonin-induced mesangial cell contraction, in a dose-dependent manner blocking 5-HT2 receptors and the voltage-operated Ca2+ channels.[3] |
別名 | LU49938, LU 49938, LU-49938 |
分子量 | 404.59 |
分子式 | C24H40N2O3 |
CAS No. | 136033-49-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (135.94 mM)
You can also refer to dose conversion for different animals. 詳細
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Nexopamil 136033-49-3 GPCR/G Protein Membrane transporter/Ion channel Metabolism Neuroscience Calcium Channel 5-HT Receptor LU49938 LU 49938 LU-49938 Inhibitor inhibitor inhibit