Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PFI-3 is a selective chemical inhibitor for SMARCA (2/4) (Kd = 89 nM)and PBI (5) bromodomains which may result in the delay and prevention of breast cancer.
説明 | PFI-3 is a selective chemical inhibitor for SMARCA (2/4) (Kd = 89 nM)and PBI (5) bromodomains which may result in the delay and prevention of breast cancer. |
ターゲット&IC50 | SMARCA4:55 nM(Kd), SMARCA2A:110 nM(Kd), SMARCA2B:72 nM(Kd) |
In vitro | PFI-3 shows a significant selectivity for PB1(5) and SMARCA2/4 over 36 other tested kinases. [1] |
別名 | PFI 3 |
分子量 | 321.37 |
分子式 | C19H19N3O2 |
CAS No. | 1819363-80-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 32.1 mg/mL(100 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
PFI-3 1819363-80-8 Chromatin/Epigenetic Epigenetic Reader Domain Inhibitor PFI 3 PFI3 inhibit inhibitor