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194

阻害剤

天然化合物

115

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T62291	Anti-melanoma agent 1
	Anti-melanoma agent 1 (Compound 5m) is an anti-melanoma agent that induces apoptosis.
T9521	CHR-6494 TFA		Others
	CHR-6494 TFA is a potent haspin inhibitor, with an IC50 of 2 nM. It inhibits histone H3T3 phosphorylation. CHR-6494 TFA induces the apoptosis of cancer cells, including melanoma and breast cancer. CHR-6494 TFA can be use...		Others
T8566	AA92593		Others
	AA92593 has been used as a selective inhibitor of melanopsin.		Others
T9148	KA2507		HDAC
	KA2507 is a potent and selective HDAC6 inibitor with an IC50 of 2.5nM.		HDAC
T9693	TBAP-001		Raf
	TBAP-001 is a RAF kinase inhibitor, with an IC50 of 62 nM in BRAF V600E kinase assay and an IC50 of 18 nM in Cell-Based Phosho-ERK Assay.		Raf
T10477	BAY-985		IκB/IKK
	BAY-985 is a potent, selective, and orally active ATP-competitive dual inhibitor of TBK1 and IKKε (IC50s: 2/30 and 2 nM for TBK1 (low/high ATP) and IKKε) with antitumor efficacy.		IκB/IKK
T3560	Desmethylanethol trithione	ADT-OH	VEGFR , Akt
	Desmethylanethol trithione (ADT-OH) is a derivative of anethole dithiolethione (ADT) and synthetic hydrogen sulfide (H2S) donor. In the in vitro glucose-oxygen deprivation (OGD) model, Desmethylanethol trithione markedly...		VEGFR , Akt
T1867	Otenaproxesul	ATB 346	Apoptosis , COX
	Otenaproxesul (ATB 346) is a novel hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity.		Apoptosis , COX
T35407	Ζ-Stat		PKC
	ζ-Stat (NSC37044), a specific and atypical inhibitor of PKC-ζ with an IC50 of 5 μM, demonstrates the ability to inhibit proliferation and induce apoptosis in melanoma cell lines, exhibiting antitumor activity in vitro[1]...		PKC
T21679	4'-bromo-Resveratrol		Sirtuin
	4'-bromo-Resveratrolis a potent inhibitor of the deacetylases sirtuin 1 (SIRT1) and 3 (SIRT3)		Sirtuin
T41286	N6-Isopentenyladenosine		Endogenous Metabolite , Autophagy
	N6-Isopentenyladenosine, an end product of the mevalonate pathway, is an autophagy inhibitor with anti-melanoma activity. N6-Isopentenyladenosine, an RNA modification found in cytokinins, regulates plant growth/different...		Endogenous Metabolite , Autophagy
T11553	Heptamidine dimethanesulfonate	SBi4211 dimethanesulfonate	Others
	Heptamidine dimethanesulfonate (SBi4211 dimethanesulfonate) serves as a potent inhibitor related to Pentamidine, targeting the calcium-binding protein S100B with a dissociation constant (Kd) of 6.9 µM. It demonstrates sp...		Others
T24269	KPT-251	KPT251	Others
	KPT-251 is a selective nuclear export inhibitor.		Others
T8745	PROTAC BRAF-V600E degrader-1	Compound 23	Raf
	PROTAC BRAF-V600E degrader-1 (Compound 23) selectively induces degradation of BRAF-V600E but not wildtype BRAF.		Raf
T1120	Dacarbazine	Imidazole Carboxamide,DTIC-Dome	Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
	Dacarbazine (DTIC-Dome) is an antineoplastic agent. It has significant activity against melanomas.
T6609	NMS-E973		HSP
	NMS-E973 is a potent and selective Hsp90 inhibitor with DC50 of <10 nM for Hsp90 binding, no activiy against a panel of 52 diverse protein kinases.		HSP
T1992	Mertansine	DM1,Maytansinoid DM1	Microtubule Associated
	Mertansine (DM1) refers to the thiol-containing maytansinoid, DM1 (N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) attached to a monoclonal antibody through reaction of the thiol group with the SPP (N-succinimidyl 4...		Microtubule Associated
T7764	CCG-222740		ROCK , Rho , Ras
	CCG-222740 is an inhibitor of Rho/MRTF pathway		ROCK , Rho , Ras
T7188	Piclidenoson	CF-101,IB-MECA	Apoptosis , Adenosine Receptor
	Piclidenoson (CF-101), a selective agonist of adenosine A3 receptor(EC50 values of 0.11 μM), induces robust anti-inflammatory effect in psoriasis patients.		Apoptosis , Adenosine Receptor
T22136	PRL-3 Inhibitor I	PRL-3 Inhibitor,BR-1	Phosphatase , Others
	PRL-3 Inhibitor I (BR-1) is a phosphatase of regenerating liver 3 (PRL-3) inhibitor which blocks the migration and invasion of metastatic cancer cells.		Phosphatase , Others
T8740	COH-SR4	COH-SR4 (Mitochondria uncoupler SR4)	Others , AMPK
	COH-SR4 (COH-SR4 (Mitochondria uncoupler SR4)) is a uncoupler of mitochondrial oxidative phosphorylation. COH-SR4 modulates amp-dependent kinase (ampk)-mammalian target of rapamycin (mtor) signaling, and inhibiting proli...		Others , AMPK
T10104	3,4-Dihydroxybenzylamine hydrobromide	NSC 263475 hydrobromide	Others , DNA/RNA Synthesis
	3,4-Dihydroxybenzylamine hydrobromide (NSC-263475 hydrobromide) inhibits DNA polymerase activity in melanoma cells and displays growth inhibitory activity in melanoma cell lines with varying degrees of tyrosinase activit...		Others , DNA/RNA Synthesis
T0509	Cloxiquine	5-Chloro-8-quinolinol,Dermofungin,Dermofongin	Antibacterial , Antibiotic , PPAR , Parasite , Antifungal
	Cloxiquine (Dermofongin) is a monohalogenated 8-hydroxyquinoline with activity against bacteria, fungi, and protozoa.		Antibacterial , Antibiotic , PPAR , Parasite , Antifungal
T23861	CAY10526	CAY-10526,BTH,CAY 10526	Prostaglandin Receptor
	CAY10526 (BTH) is a selective mPGES-1 inhibitor that acts as an inhibitor of the NF-κB signaling pathway.		Prostaglandin Receptor
T36573	NHWD-870		Apoptosis , Epigenetic Reader Domain
	NHWD-870 is an effective and selective inhibitor of BET family bromodomain only binding to BRD2, BRD3, BRD4 (IC50 = 2.7 nM), and BRDT. NHWD-870 exhibits potent anti-tumor efficacies and suppresses cancer cell-macrophage ...		Apoptosis , Epigenetic Reader Domain
T10395L	ATM-3507		Others
			Others
T27792	L-Alaninol	2-Aminopropanol
	L-Alaninol, an amino acid derivative, inhibits melanoma proliferation and increases cytrochrome C reductase and tau-glutamyl transpeptidase.
T11854	Lipofermata		Others , Antibacterial
	Lipofermata is a fatty acid transport protein (FATP) inhibitor that prevents lipid transport to melanoma cells and reduces melanoma growth and invasion.		Others , Antibacterial
T35300	Zeniplatin	Zeniplatinum	Others
	Zeniplatin (Zeniplatinum) is a new cisplatin complex with anticancer activity for the treatment of metastatic melanoma and kidney cancer.		Others
T27454	GSK2008607		Raf
	GSK2008607 is a potent B-RafV600E inhibitor with anticancer activity and can be used to study breast, colorectal, melanoma, thyroid, and ovarian cancers.		Raf
T28001	MDK-6983	MDK-6983,Compound 6k,Autophagy inhibitor 6k,MDK6983	Autophagy
	MDK-6983 (MDK-6983) is an inhibitor of autophagy and disrupts the dynamics of actin cytoskeleton in human melanoma cells.		Autophagy
T8654	Plx-4032	Vemurafenib	Raf
	Plx-4032 (Vemurafenib) is a small-molecule B-Raf inhibitor for the potential treatment of malignant melanoma.		Raf
T28206	NSC49652	NSC 49652,NSC-49652	Apoptosis
	NSC49652 triggers apoptotic cell death dependent on p75NTR and JNK activity in neurons and melanoma cells, and inhibits tumor growth in a melanoma mouse model.		Apoptosis
T16871	Semustine		DNA Alkylator/Crosslinker
	Semustine, a DNA alkylating agent, is a cancer chemotherapy compound that is nephrotoxic in patients with malignant melanoma receiving adjuvant chemotherapy for the adjuvant treatment of leukemia.		DNA Alkylator/Crosslinker
T7712L	Disomotide TFA 181477-43-0(free base)		Others
	Disomotide TFA is an oligopeptide for the treatment of melanoma.		Others
T7088	Diflubenzuron	Dimilin,Difubenzuron,Larvakil,Difluron	P450
	Diflubenzuron (Larvakil) is a benzoyl-urea insecticide, found to be a potent inhibitor of melanosome synthesis in mouse melanoma cells. Diflubenzuron has also been shown to inhibit TCDD-induced CYP1A1 expression in HepG2...		P450
T77118	Plozalizumab	MLN-1202	CCR
	Plozalizumab (MLN-1202) is a humanized selective and potent anti-CCR2 antibody.Plozalizumab has antitumor activity.Plozalizumab is used in the study of malignant melanoma.		CCR
T28145	ND-322 HCl	ND 322 Hydrochloride,ND322 Hydrochloride,ND-322 Hydrochloride,ND322 HCl	MMP
	ND-322 HCl (ND 322 Hydrochloride) is a selective inhibitor of MT1-MMP and MMP2 and reduces in vitro melanoma cell growth, migration and invasion.		MMP
T35688	MTIC	NSC 407347	Drug Metabolite
	MTIC is the active metabolite of Temozolomide (TMZ) with anticancer and antitumor activity and is used in the study of melanoma.3'-Sialyllactose (3'-SL) sodium is a prebiotic with anti-inflammatory activity.		Drug Metabolite
T9869	N-[2-(diethylamino)ethyl]-2-iodobenzamide		Others
	N-[2-(diethylamino)ethyl]-2-iodobenzamide is a radiopharmaceutical for the scintigraphic detection of melanoma and metastases.		Others
T77706	4-Borono-L-phenylalanine	(s)-2-amino-3-(4-boronophenyl)propanoic acid,L-p-Boronophenylalanine	Others
	4-Borono-L-phenylalanine has antitumor activity and may be used in clinical trials of boron neutron capture therapy for the treatment of melanoma and glioblastoma multiforme.		Others
T6855	HA15		Apoptosis , GPR , Others , HSP , Autophagy
	HA15 targets specifically BiP/GRP78/HSPA5. HA15 exhibits anti-cancerous activity on all melanoma cells tested, including cells isolated from patients and cells that developed resistance to BRAF inhibitors.		Apoptosis , GPR , Others , HSP , Autophagy
T4356	POL1-IN-1	Compound 3A	DNA/RNA Synthesis
	POL1-IN-1 (Compound 3A) can effectively inhibit the transcription of RNA polymerase I in the A375 malignant melanoma cell line but has no effect on polymerase II.		DNA/RNA Synthesis
T2503	PAC-1	Procaspase activating compound 1	Apoptosis , Caspase , Autophagy
	PAC-1 (Procaspase activating compound 1) has been used in trials studying the treatment of Lymphoma, Melanoma, Solid Tumors, Breast Cancer, and Thoracic Cancers, among others.		Apoptosis , Caspase , Autophagy
T12731	RIPK1-IN-7		RIP kinase
	RIPK1-IN-7 is a potent and selective inhibitor of RIPK1(Kd of 4 nM and an enzymatic IC50 of 11 nM),andexhibits excellent antimetastasis activity in the experimental B16 melanoma lung metastasis model.		RIP kinase
T17195	UC-112		Others
	UC-112 is a novel potent IAP inhibitor and potently inhibits cell growth in two human melanoma and two human prostate cancer cell lines (IC50=0.7-3.4 uM).		Others
T11209	EOAI3402143		DUB
	EOAI3402143 inhibits Usp9x and Usp24 activity, increases tumor cell apoptosis. EOAI3402143 phenocopies the FAS induction and apoptotic sensitization of Usp5 knockdown and fully blocks melanoma tumor growth.		DUB
T77743	TT-012		Others
	TT-012 has anti-tumor activity, selectively binds dynamic MITF and disrupts the dimer formation and DNA binding of the latter. TT-012 can inhibit the transcription of MITF in B16F10 melanoma cells. TT-012 inhibited the g...		Others
TP1097	Melanotan I	[Nle4,D-Phe7]-α-MSH,Afamelanotide,MT-I	Others
	Melanotan I is a non-specific melanocortin receptor (MCR) agonist, an α-melanocyte-stimulating hormone (α-MSH) analog, which is injected subcutaneously to increase the amount of melanin in the skin Melanotan I is used as...		Others
T77649	HTYR/AbTYR-IN-1		Tyrosinase
	hTYR/AbTYR-IN-1 is a dual hTYR/AbTYR inhibitor with inhibitory effects on hTYR and AbTYR, with IC50s of 5.4 μM and 3.52 μM, respectively. hTYR/AbTYR-IN-1 can be used for the study of hyperpigmentation and melanoma in hum...		Tyrosinase

Compounds

Anti-melanoma agent 1

Desmethylanethol trithione

Target: Apoptosis, COX

N6-Isopentenyladenosine

T41286

Synonym:

Target: Endogenous Metabolite, Autophagy

Heptamidine dimethanesulfonate

T11553

Synonym: SBi4211 dimethanesulfonate

PROTAC BRAF-V600E degrader-1

Synonym: Imidazole Carboxamide,DTIC-Dome

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

Synonym: DM1,Maytansinoid DM1

Target: Microtubule Associated

CCG-222740

T7764

Synonym:

Target: ROCK, Rho, Ras

Piclidenoson

T7188

Synonym: CF-101,IB-MECA

Target: Apoptosis, Adenosine Receptor

PRL-3 Inhibitor I

T22136

Synonym: PRL-3 Inhibitor,BR-1

Target: Phosphatase, Others

COH-SR4

T8740

Synonym: COH-SR4 (Mitochondria uncoupler SR4)

Target: Others, AMPK

3,4-Dihydroxybenzylamine hydrobromide

T10104

Synonym: NSC 263475 hydrobromide

Target: Others, DNA/RNA Synthesis

Cloxiquine

T0509

Synonym: 5-Chloro-8-quinolinol,Dermofungin,Dermofongin

Target: Antibacterial, Antibiotic, PPAR, Parasite, Antifungal

CAY10526

T23861

Synonym: CAY-10526,BTH,CAY 10526

Target: Prostaglandin Receptor

NHWD-870

T36573

Synonym:

Target: Apoptosis, Epigenetic Reader Domain

Synonym: 2-Aminopropanol

Target: Others, Antibacterial

Zeniplatin

T35300

Synonym: Zeniplatinum

Synonym: MDK-6983,Compound 6k,Autophagy inhibitor 6k,MDK6983

Synonym: NSC 49652,NSC-49652

Target: DNA Alkylator/Crosslinker

Disomotide TFA 181477-43-0(free base)

Synonym: Dimilin,Difubenzuron,Larvakil,Difluron

Synonym: ND 322 Hydrochloride,ND322 Hydrochloride,ND-322 Hydrochloride,ND322 HCl

Target: Drug Metabolite

N-[2-(diethylamino)ethyl]-2-iodobenzamide

T9869

Synonym:

Target: Others

4-Borono-L-phenylalanine

T77706

Synonym: (s)-2-amino-3-(4-boronophenyl)propanoic acid,L-p-Boronophenylalanine

Target: Apoptosis, GPR, Others, HSP, Autophagy

POL1-IN-1

T4356

Synonym: Compound 3A

Target: DNA/RNA Synthesis

PAC-1

T2503

Synonym: Procaspase activating compound 1

Target: Apoptosis, Caspase, Autophagy

Synonym: [Nle4,D-Phe7]-α-MSH,Afamelanotide,MT-I

カタログ番号	製品名	別名	ターゲット
T9135	Epirosmanol		Others
	Epirosmanol is a diterpenoid containing a lactone moiety. Epirosmanol is a very weakly basic (essentially neutral) compound (based on its pKa).		Others
TN2069	Picrocrocin		Apoptosis
	Picrocrocin is a natural product		Apoptosis
T5S0055	Chelidonine	Helidonine,Khelidonin,Stylophorin	Apoptosis , Others , Influenza Virus
	1. Chelidonine (Stylophorin) isolated from Chelidonium majus efficiently induced apoptosis in HeLa cells through possible alteration of p38-p53 and AKT/PI3 kinase signalling pathways. 2. Chelidonine is a promising model ...		Apoptosis , Others , Influenza Virus
T1310	2-Thiouracil	Thiouracil,Deracil	Thyroid hormone receptor(THR) , NO Synthase
	2-Thiouracil (Deracil) is a thiolated uracil derivative that is a known anti-hyperthyroid agent.		Thyroid hormone receptor(THR) , NO Synthase
T2819	Methyl p-coumarate	Methyl 4-hydroxycinnamate	Others , Antifungal
	"Methyl 4-hydroxycinnamate is an esterified derivative of p-coumaric acid isolated from the flowers of Trixis michuacana var. longifolia, exhibiting antibacterial and anti-melanogenesis properties."		Others , Antifungal
T7203	Oglufanide	L-Glutamyl-L-tryptophan,H-Glu-Trp-OH	VEGFR , HCV Protease , Endogenous Metabolite
	Oglufanide (H-Glu-Trp-OH) is a naturally occurring thymic immunomodulator,and inhibits vascular endothelial growth factor (VEGF).		VEGFR , HCV Protease , Endogenous Metabolite
T4745	4-Carboxyquinoline	QUINOLINE-4-CARBOXYLIC ACID,4-Quinolinecarboxylic acid	Others , Endogenous Metabolite
	4-Carboxyquinoline (4-Quinolinecarboxylic acid) showed anti-tumor activity against L1210 leukemia and B16 melanoma.		Others , Endogenous Metabolite
TN6705	Graveoline	2-(Benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one,Foliosine	Autophagy
	Graveoline (2-(Benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one) is an apoptosis and autophagy inducer in skin melanoma cancer cells		Autophagy
TQ0213	Bruceantin	(-)-Bruceantin,NCI165563,NSC165563	Others
			Others
TN3594	Cardanol (C15:1)		Apoptosis , Others
	Cardanol (C15:1), found in cashew nut shell liquid, induces mitochondria-associated apoptosis in human melanoma cells.		Apoptosis , Others
T5646	Cinnamic acid	3-Phenylacrylic acid,β-Phenylacrylic acid	Endogenous Metabolite
	Cinnamic acid (β-Phenylacrylic acid) has potential use in cancer intervention,The concentration causing a 50% reduction of cell proliferation (IC50) ranged from 1 to 4.5 mM in glioblastoma, melanoma, prostate and lung ca...		Endogenous Metabolite
T3S0153	Xanthatin		Apoptosis , VEGFR , Lipoxygenase , Wnt/beta-catenin , Antibacterial
	1. Xanthatin has cytotoxic activity. 2. Xanthatin has antibacterial and antifungal activies against MRSA. 3. Xanthatin may have therapeutic potential against NSCLC. 4. Xanthatin can inhibit murine melanoma B16-F1 cell pr...
T3810	Saikosaponin B2		Others , HCV Protease
	Saikosaponin B2 acts on HCV E2 and inhibits infection by several genotypic strains and prevents binding of serum-derived HCV onto hepatoma cells. Saikosaponin B2 (5 μM) induces differentiation of B16 melanoma cells, with...		Others , HCV Protease
T5S0506	Rotundic acid	Rutundic acid	Apoptosis , Others , p38 MAPK , Akt , mTOR
	Rotundic acid (Rutundic acid), a natural compound, exhibit cytotoxic activities toward human hepatocellular carcinoma (HepG2), malignant melanoma (A375), SCLC (NCI-H446), breast cancer (MCF-7), and colon cancer (HT-29) c...		Apoptosis , Others , p38 MAPK , Akt , mTOR
TN1873	Lirinidine		Others
	(+)-Lirinidine has antioxidative activity, and it can significantly inhibit the proliferation of melanoma cells; it also shows potent inhibition of melanogenesis. Lirinidine exhibits significant inhibition of collagen, a...		Others
TN6339	(R)-5-Hydroxy-1,7-diphenylheptan-3-one	(5R)-Dihydroyashabushiketol	Others
	(R)-5-Hydroxy-1,7-diphenylheptan-3-one ((5R)-Dihydroyashabushiketol) is extracted from the rhizomes of Alpinia officinarum, a Chinese medicinal herb. (R)-5-Hydroxy-1,7-diphenylheptan-3-one inhibits melanogenesis in theop...		Others
T4518	Licochalcone D		ERK , NF-κB
	Licochalcone D may be a potential drug for human melanoma treatment by inhibiting proliferation, inducing apoptosis via the mitochondrial pathway and blocking cell migration and invasion. Licochalcone D has cardioprotect...		ERK , NF-κB
T2P2806	Hederacolchiside A1	Raddeanoside R13	Apoptosis , ERK , MEK , Akt , PI3K , Parasite , mTOR
	Hederacolchiside A1 (Raddeanoside R13) shows anti-leishmanial activity, it exhibits a strong antiproliferative activity on all stages of development of the parasite by altering membrane integrity and potential. Hederacol...		Apoptosis , ERK , MEK , Akt , PI3K , Parasite , mTOR
T7052	Gnetol		Tyrosinase , COX , HDAC , AChR
	Gnetol competitivity inhibits butyrylcholinesterase (IC50: 1.3 uM). Gnetol has a strong inhibitory effect on murine tyrosinase activity. Gnetol significantly suppresses melanin biosynthesis in murine B16 melanoma cells. ...		Tyrosinase , COX , HDAC , AChR
TN6972	Methyl pentadecanoate		Others
	Methyl pentadecanoate is a natural product.		Others
TN1516	Cnidicin		NOS , NO Synthase
	Cnidicin has anti-allergic and anti-inflammatory activity, it inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells(IC50 value, 7.5 microM). Cnidicin exhibits a significant inhibition on the pr...		NOS , NO Synthase
T3S0645	N-trans-Feruloyltyramine	Feruloyltyramine,N-Feruloyltyramine,Moupinamide	Others , COX
	1. N-trans-Feruloyltyramine (Feruloyltyramine)(NTF) has hepatoprotective effect. 2. NTF has antioxidative activity against Aβ(1-42)-induced neuronal death. 3. NTF is likely to inhibit COX enzymes, thereby suppressing P-s...		Others , COX
TN2601	12-O-Methylcarnosic acid		Reductase
	12-O-Methylcarnosic acid is a diterpene carnosic acid isolated from Salvia microphylla, is an active constituent of 5α-Reductase inhibition with an IC50 value of 61.7 μM. 12-O-Methylcarnosic acid has Antioxidant activity...		Reductase
T4S1551	Cinnamaldehyde	Cinnamic Aldehyde	HIF
	1. Cinnamaldehyde (Cinnamic Aldehyde) has antipyretic activity. 2. Cinnamaldehyde is a sedative agent. 3. Cinnamaldehyde inhibits invasive capabilities of MDA-MB-435S cells was correlated with down-regulating the express...		HIF
TCS2170	2,5-Dihydroxyacetophenone	Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP	ERK , NF-κB , Tyrosinase
	1. 2,5-Dihydroxyacetophenone (Quinacetophenone) possess anti-anxiety, and neuroprotective qualities. 2. 2,5-Dihydroxyacetophenone (Quinacetophenone) reatment can induce a sustained activation of JNK, ERK1/2, and p38 MAPK...		ERK , NF-κB , Tyrosinase
T2924	Phloretin	Dihydronaringenin,NSC 407292,RJC 02792	SGLT , transporter , Endogenous Metabolite
	Phloretin (NSC-407292) is a well-known inhibitor of eukaryotic urea transporters, blocks VacA-mediated urea and ion transport. Phloretin is a dihydrochalcone, a type of natural phenols. It can be found in apple tree leav...		SGLT , transporter , Endogenous Metabolite
T3229	Cytochalasin D		ATPase , p38 MAPK , Calcium Channel , Akt , PI3K
	Cytochalasin D is an actin inhibitor, the removal of actin stress fibers is crucial for the chondrogenic differentiation. It may be an inhibitor of some fertilization processes such as sperm penetration or sperm head dec...		ATPase , p38 MAPK , Calcium Channel , Akt , PI3K
T4S0797	Berberine	Berberin,Umbellatine	Reactive Oxygen Species , Topoisomerase , Endogenous Metabolite , Antibacterial , Antibiotic , Autophagy
	1. Berberine (Umbellatine) is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism. 2. Berberine may as a broad-spectrum anti-microbial medicine, a complementary therapeutic agent for HIV/AIDS. 3....
T24075	Fusarochromanone	NSC-627608,FC101,NSC 627608,FC-101,FC 101
	Fusarochromanone is a melanoma growth inhibitor.
T23773	Barbigerone	Barubigeron
	Barbigerone is a tumor angiogenesis, growth, and metastasis inhibitor in melanoma.
TN5300	Citrostadienol
	Citrostadienol shows cytotoxic activity against B16F10 melanoma cells.
TN5329	Epitulipinolide diepoxide
	Epitulipinolide diepoxide has antioxidative and chemopreventive activities in skin melanoma cells, can significantly inhibit the proliferation of melanoma cells, it possesses cytotoxic activity against KB cells.
TN5212	Uvedalin		Others
	Uvedalin shows cytotoxicity against HeLa, HL-60, and Murine B16-F10 melanoma cell lines.		Others
TN3682	Clerosterol glucoside		Others
	Clerosterol exerts its cytotoxic effect in A2058 human melanoma cells by caspases-dependent apoptosis.		Others
TN3605	Casegravol		Others
	Casegravol shows antiproliferative activity against human gastric adenocarcinoma (MK-1), human uterus carcinoma (HeLa), and murine melanoma (B16F10) cells.		Others
TN4642	Neorauflavane		Tyrosinase
	Neorauflavane shows tyrosinase inhibition, it can inhibit tyrosinase monophenolase activity with an IC50 of 30 nM, it also can efficiently reduce melanin content in B16 melanoma cells with 12.95 uM of IC50.		Tyrosinase
TN1486	Chimonanthine		Others
	(-)-Chimonanthine (IC50 = 0.93 μM) shows potent inhibitory effects on melanogenesis in theophylline-stimulated murine B16 melanoma 4A5 cells.		Others
T28522	Reticulol
	Reticulol is an isocoumarin derivative produced by certain species of Streptomyces. Reticulol inhibits cAMP phosphodiesterase (IC50 = 41 µM). Recticulol (M.W. 222.2) exhibits a potent in vitro cytotoxicity against the hu...
TN3644	Chlorophorin		Tyrosinase , Antifection
	Chlorophorin shows high anti-protozoal activity with an MIC of 0.25 microg/ml. Chlorophorin can strongly inhibit mushroom tyrosinase activity with IC50 values of 2.5 ± 0.408 uM; it inhibits α-melanocyte-stimulating hormo...		Tyrosinase , Antifection
TN6054	Norglaucine hydrochloride
	(+)-Norglaucine shows cytotoxic activity toward the tumor cell lines B16-F10 (mouse melanoma), HepG2 (human hepatocellular carcinoma), K562 (human chronic myelocytic leukemia) and HL-60 (human promyelocytic leukemia) and...
TN2923	3'-Deoxy-4-O-methylsappanol		Tyrosinase
	3'-Deoxy-4-O-methylsappanol shows moderate cytotoxicities against cultured human melanoma HMV-II cells with the IC50 value of 872.0 uM ± 2.4.		Tyrosinase
T2S0799	Noroxyhydrastinine		Tyrosinase
	Noroxyhydrastinine exhibits potent melanogenesis-inhibitory activities, it inhibits melanogenesis, at least in part, by inhibiting the expression of protein levels of tyrosinase, TRP-1, and TRP-2 in α-MSH-stimulated B16 ...		Tyrosinase
TN4699	Ohchinin		Others
	Ohchinin exhibits potent inhibitory activities with 26 - 66% reduction of melanin content at 100 μm concentration with almost no or low toxicity to the B16 melanoma cells (70 - 99% cell viability at 100 μm).		Others
TN6010	Picrasidine S
	Picrasidine S shows the potent cytotoxicity against human HeLa cervical, gastric MKN-28, and mouse melanoma B-16 cancer cells, it also shows the potent antibacterial activity against two strains of pathogenic bacteria me...
TN3681	Clerosterol		BCL , Caspase
	Clerosterol as a precursor of cyasterone, isocyasterone and 29-norcyasterone in biosynthesis of phytoecdysteroids of Ajuga hairy roots. Clerosterol exerts its cytotoxic effect in A2058 human melanoma cells by caspases-de...		BCL , Caspase
TN3842	Diarylcomosol III		Others
	Diarylcomosol III shows inhibitory effects on melanogenesis in B16 melanoma cells, it is a promising therapeutic agent for the treatment of skin disorders.		Others
TN1583	Dihydromorin		TRP/TRPV Channel
	trans-Dihydromorin is an effective hypopigmenting agent in normal skin cells, hypopigmenting agents effective in melanoma system may not be effective on normal melanocytes, indicating that a non-tumor melanocyte system i...		TRP/TRPV Channel
T73640	Pancratistatin
	Pancratistatin, an isoquinoline alkaloid extracted from Hymenocallis littoralis, induces apoptosis in human melanoma cells and is utilized in researching neuroblastoma, leukemia, and breast cancer [1].
T72965	Inuviscolide
	Inuviscolide, an apoptosis inducer, demonstrates the capacity to induce G2/M arrest in human melanoma cell lines. Exhibiting both antineoplastic and anti-inflammatory activities, this compound shows potential in cancer t...
TN3726	Cudraflavone B		IκB/IKK , MAO , ROS , Akt , COX , PI3K , Nrf2 , Autophagy
	Cudraflavone B has anti-proliferative activity, mouse brain monoamine oxidase (MAO) inhibitory effects, apoptotic actions in human gastric carcinoma cells and mouse melanoma cells, and hepatoprotective activity. It may b...		IκB/IKK , MAO , ROS , Akt , COX , PI3K , Nrf2 , Autophagy
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天然物製品

Synonym: Helidonine,Khelidonin,Stylophorin

Target: Apoptosis, Others, Influenza Virus

2-Thiouracil

T1310

Synonym: Thiouracil,Deracil

Target: Thyroid hormone receptor(THR), NO Synthase

Methyl p-coumarate

T2819

Synonym: Methyl 4-hydroxycinnamate

Target: Others, Antifungal

Oglufanide

T7203

Synonym: L-Glutamyl-L-tryptophan,H-Glu-Trp-OH

Target: VEGFR, HCV Protease, Endogenous Metabolite

4-Carboxyquinoline

T4745

Synonym: QUINOLINE-4-CARBOXYLIC ACID,4-Quinolinecarboxylic acid

Target: Others, Endogenous Metabolite

Graveoline

TN6705

Synonym: 2-(Benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one,Foliosine

Target: Autophagy

Bruceantin

TQ0213

Synonym: (-)-Bruceantin,NCI165563,NSC165563

Target: Apoptosis, Others

Cinnamic acid

T5646

Synonym: 3-Phenylacrylic acid,β-Phenylacrylic acid

Target: Endogenous Metabolite

Xanthatin

T3S0153

Synonym:

Target: Apoptosis, VEGFR, Lipoxygenase, Wnt/beta-catenin, Antibacterial

Saikosaponin B2

T3810

Synonym:

Target: Others, HCV Protease

Rotundic acid

T5S0506

Synonym: Rutundic acid

Target: Apoptosis, Others, p38 MAPK, Akt, mTOR

(R)-5-Hydroxy-1,7-diphenylheptan-3-one

TN6339

Synonym: (5R)-Dihydroyashabushiketol

Synonym: Raddeanoside R13

Target: Apoptosis, ERK, MEK, Akt, PI3K, Parasite, mTOR

Gnetol

T7052

Synonym:

Target: Tyrosinase, COX, HDAC, AChR

Methyl pentadecanoate

Target: NOS, NO Synthase

N-trans-Feruloyltyramine

T3S0645

Synonym: Feruloyltyramine,N-Feruloyltyramine,Moupinamide

Target: Others, COX

12-O-Methylcarnosic acid

Synonym: Cinnamic Aldehyde

Target: HIF

2,5-Dihydroxyacetophenone

TCS2170

Synonym: Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP

Target: ERK, NF-κB, Tyrosinase

Phloretin

T2924

Synonym: Dihydronaringenin,NSC 407292,RJC 02792

Target: SGLT, transporter, Endogenous Metabolite

Cytochalasin D

T3229

Synonym:

Target: ATPase, p38 MAPK, Calcium Channel, Akt, PI3K

Berberine

T4S0797

Synonym: Berberin,Umbellatine

Target: Reactive Oxygen Species, Topoisomerase, Endogenous Metabolite, Antibacterial, Antibiotic, Autophagy

Fusarochromanone

T24075

Synonym: NSC-627608,FC101,NSC 627608,FC-101,FC 101

Epitulipinolide diepoxide

Clerosterol glucoside

Target: Tyrosinase, Antifection

Norglaucine hydrochloride

TN6054

Synonym:

Target:

3'-Deoxy-4-O-methylsappanol

Target: TRP/TRPV Channel

Target: IκB/IKK, MAO, ROS, Akt, COX, PI3K, Nrf2, Autophagy

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-01137	MIA Protein, Human, Recombinant (His)	Human	E. coli
	Melanoma Inhibitory Activity Protein (MIA) is an autocrine growth regulatory protein secreted from chondrocytes and malignant melanoma cells, which was the first discovered member of a family of secreted cytokines termed...
TMPY-01775	AIM2 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	AIM2, Absent In Melanoma 2 is a member of the interferon-inducible HIN-200 protein family that contains an amino-terminal pyrin domain and a carboxy-terminal oligonucleotide/oligosaccharide-binding domain, senses cytopla...
TMPY-06064	CD146/MCAM Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	The CD146 antigen, also known as melanoma cell adhesion molecule (MCAM) and MUC18, is an integral membrane glycoprotein belonging to the immunoglobulin superfamily. CD146 contains the characteristic immunoglobulin-like d...
TMPY-01034	CD146/MCAM Protein, Human, Recombinant (His)	Human	HEK293
	The CD146 antigen, also known as melanoma cell adhesion molecule (MCAM) and MUC18, is an integral membrane glycoprotein belonging to the immunoglobulin superfamily. CD146 contains the characteristic immunoglobulin-like d...
TMPY-00879	CD146/MCAM Protein, Human, Recombinant (hFc)	Human	HEK293
	The CD146 antigen, also known as melanoma cell adhesion molecule (MCAM) and MUC18, is an integral membrane glycoprotein belonging to the immunoglobulin superfamily. CD146 contains the characteristic immunoglobulin-like d...
TMPH-01086	CSPG4 Protein, Human, Recombinant (His & Myc)	Human	HEK293
	Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon rege...
TMPK-01493	HLA-A*01:01&B2M&MAGE-A3 (EVDPIGHLY) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293
	Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine im...
TMPY-00008	CXCL1 Protein, Rat, Recombinant	Rat	E. coli
	The Chemokine (C-X-C motif) Ligand 1, CXCL1, is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GRO?, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimu...
TMPK-01495	HLA-A*01:01&B2M&MAGE-A3 (EVDPIGHLY) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293
	Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine im...
TMPY-02502	CD146/MCAM Protein, Mouse, Recombinant (His)	Mouse	HEK293
	The CD146 antigen, also known as melanoma cell adhesion molecule (MCAM) and MUC18, is an integral membrane glycoprotein belonging to the immunoglobulin superfamily. CD146 contains the characteristic immunoglobulin-like d...
TMPY-00433	CXCL1 Protein, Mouse, Recombinant	Mouse	E. coli
	The Chemokine (C-X-C motif) Ligand 1, CXCL1, is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GRO?, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimu...
TMPK-01473	HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293
	Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine im...
TMPK-01472	HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293
	Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine im...
TMPY-02868	CXCL1 Protein, Human, Recombinant	Human	E. coli
	The Chemokine (C-X-C motif) Ligand 1, CXCL1, is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GRO?, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimu...
TMPY-02180	CXCL1 Protein, Human, Recombinant (His & NusA)	Human	E. coli
	The Chemokine (C-X-C motif) Ligand 1, CXCL1, is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GRO?, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimu...
TMPY-02026	CXCL1 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	The Chemokine (C-X-C motif) Ligand 1, CXCL1, is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GRO?, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimu...
TMPH-03526	Cap8A Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	in vitro E. coli expression system
	May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate comp...
TMPJ-00011	CXCL2 Protein, Mouse, Recombinant	Mouse	E. coli
	C-X-C motif chemokine 2 (CXCL2,MIP-2) belongs to the intercrine alpha (chemokine CxC) family. It was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin...
TMPY-03564	TSPAN8 Protein, Human, Recombinant (His)	Human	HEK293
	Tetraspanin 8 (TSPAN8) as an important modulator of melanoma invasiveness, and several of its transcriptional regulators, which affect TSPAN8 expression during melanoma progression toward an invasive stage. p53 as a nega...
TMPY-02087	IL-24 Protein, Human, Recombinant (His)	Human	HEK293
	Interleukin-24 (IL-24) also known as Melanoma differentiation-associated gene 7 protein (MDA-7) is a member of the IL10 family of cytokines. IL-24/MDA-7/IL24 can induce apoptosis selectively in various cancer cells. Over...
TMPY-02234	CXCL9 Protein, Human, Recombinant	Human	E. coli
	Chemokine (C-X-C motif) ligand 9 (CXCL9), also known as Monokine induced by gamma interferon (MIG), is a small cytokine belonging to the CXC chemokine family. The function of this chemokine has not been specifically defi...
TMPY-00775	DKK1 Protein, Human, Recombinant (His)	Human	HEK293
	Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 ...
TMPY-04811	DKK1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 ...
TMPY-04333	LRRC15 Protein, Human, Recombinant (hFc)	Human	HEK293
	LRRC15 (Leucine-Rich Repeat Containing 15) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. The tumor antigen 15-leucine-rich repeat-containing membrane protein (LRRC15) is a transmemb...
TMPY-01174	DKK1 Protein, Rhesus, Recombinant (N256Q, His)	Rhesus	HEK293
	Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 ...
TMPY-01283	Glypican 3/GPC3 Protein, Human, Recombinant (His)	Human	HEK293
	Glypican-3, also known as Intestinal protein OCI-5, GPC3, and OCI5, is a member of the glypican family. It belongs to the glypican family and is highly expressed in the lung, liver, and kidney. It is a heparan sulfate pr...
TMPY-00502	Glypican 3/GPC3 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus-Insect Cells
	Glypican-3, also known as Intestinal protein OCI-5, GPC3, and OCI5, is a member of the glypican family. It belongs to the glypican family and is highly expressed in the lung, liver, and kidney. It is a heparan sulfate pr...
TMPY-02154	FAP Protein, Human, Recombinant (His)	Human	HEK293
	Seprase, also known as 17 kDa melanoma membrane-bound gelatinase , Fibroblast activation protein alpha, Integral membrane serine protease and FAP, is a single-pass type II membrane protein which belongs to thepeptidase S...
TMPY-04962	FAP Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Seprase, also known as 17 kDa melanoma membrane-bound gelatinase , Fibroblast activation protein alpha, Integral membrane serine protease and FAP, is a single-pass type II membrane protein which belongs to thepeptidase S...
TMPY-04922	FAP Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	Seprase, also known as 17 kDa melanoma membrane-bound gelatinase , Fibroblast activation protein alpha, Integral membrane serine protease and FAP, is a single-pass type II membrane protein which belongs to thepeptidase S...
TMPY-01923	CD25/IL2R alpha Protein, Mouse, Recombinant (His)	Mouse	HEK293
	CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ...
TMPY-05644	CD25/IL2R alpha Protein, Rhesus, Recombinant (His & Avi), Biotinylated	Rhesus	HEK293
	CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ...
TMPY-01103	CD25/IL2R alpha Protein, Human, Recombinant (His)	Human	HEK293
	CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ...
TMPY-05584	CD25/IL2R alpha Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ...
TMPY-05090	CD25/IL2R alpha Protein, Rat, Recombinant (His)	Rat	Baculovirus-Insect Cells
	CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ...
TMPY-03644	CD25/IL2R alpha Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ...
TMPY-03776	CD25/IL2R alpha Protein, Cynomolgus, Recombinant	Cynomolgus	HEK293
	CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ...
TMPY-02788	IL-2 Protein, Mouse, Recombinant	Mouse	E. coli
	Interleukin-2, also known as a T-cell growth factor, TCGF, Aldesleukin, and IL2, is a secreted protein that belongs to the IL-2 family. Interleukin-2 / IL-2 was the first interleukin molecule to be discovered. Interleuki...
TMPY-02457	IL-2 Protein, Rat, Recombinant	Rat	E. coli
	Interleukin-2, also known as a T-cell growth factor, TCGF, Aldesleukin, and IL2, is a secreted protein that belongs to the IL-2 family. Interleukin-2 / IL-2 was the first interleukin molecule to be discovered. Interleuki...
TMPK-01072	AMIGO2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Bromodomain and extraterminal domain inhibitors (BETi) represent promising therapeutic agents for metastatic melanoma, yet their mechanism of action remains unclear. Here we interrogated the transcriptional effects of BE...
TMPJ-01145	ABCB5 Protein, Human, Recombinant (Trx)	Human	E. coli
	ATP-binding cassette sub-family B member 5(ABCB5) is a plasma membrane-spanning protein. ABCB5 is principally expressed in physiological skin and human malignant melanoma. ABCB5 has been suggested to regulate skin progen...
TMPK-01469	HLA-A*02:01&B2M&MART-1 (ELAGIGILTV) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293
	Melanoma antigen recognized by T cell-1 (Mart-1), one of the melanosome-specific proteins, also recognized by cytotoxicity T lymphocytes as a marker. Mart-1 is considered to play a critical role in the immunotherapy for ...
TMPK-01441	HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293
	PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumor...
TMPK-00660	AMIGO2 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Bromodomain and extraterminal domain inhibitors (BETi) represent promising therapeutic agents for metastatic melanoma, yet their mechanism of action remains unclear. Here we interrogated the transcriptional effects of BE...
TMPY-03675	TSPAN8 Protein, Human, Recombinant (mFc)	Human	HEK293
	Tetraspanin 8 (TSPAN8) as an important modulator of melanoma invasiveness, and several of its transcriptional regulators, which affect TSPAN8 expression during melanoma progression toward an invasive stage. p53 as a nega...
TMPK-01447	HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293
	PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumor...
TMPK-01454	HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293
	PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumor...
TMPK-01455	HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293
	PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumor...
TMPK-01406	HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled	Human	HEK293
	PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumor...
TMPK-01468	HLA-A*02:01&B2M&MART-1 (ELAGIGILTV) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293
	Melanoma antigen recognized by T cell-1 (Mart-1), one of the melanosome-specific proteins, also recognized by cytotoxicity T lymphocytes as a marker. Mart-1 is considered to play a critical role in the immunotherapy for ...
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MIA Protein, Human, Recombinant (His)

TMPJ-01137

Species: Human

Expression System: E. coli

AIM2 Protein, Human, Recombinant (GST)

TMPY-01775

Species: Human

Expression System: Baculovirus-Insect Cells

CD146/MCAM Protein, Human, Recombinant (His), Biotinylated

TMPY-06064

Species: Human

Expression System: HEK293

CD146/MCAM Protein, Human, Recombinant (His)

TMPY-01034

Species: Human

Expression System: HEK293

CD146/MCAM Protein, Human, Recombinant (hFc)

TMPY-00879

Species: Human

Expression System: HEK293

CSPG4 Protein, Human, Recombinant (His & Myc)

TMPH-01086

Species: Human

Expression System: HEK293

HLA-A*01:01&B2M&MAGE-A3 (EVDPIGHLY) Tetramer Protein, Human, MHC (His & Avi)

TMPK-01493

Species: Human

Expression System: HEK293

CXCL1 Protein, Rat, Recombinant

TMPY-00008

Species: Rat

Expression System: E. coli

HLA-A*01:01&B2M&MAGE-A3 (EVDPIGHLY) Monomer Protein, Human, MHC (His & Avi)

TMPK-01495

Species: Human

Expression System: HEK293

CD146/MCAM Protein, Mouse, Recombinant (His)

TMPY-02502

Species: Mouse

Expression System: HEK293

CXCL1 Protein, Mouse, Recombinant

TMPY-00433

Species: Mouse

Expression System: E. coli

HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Monomer Protein, Human, MHC (His & Avi), Biotinylated

TMPK-01473

Species: Human

Expression System: HEK293

HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Tetramer Protein, Human, MHC (His & Avi)

TMPK-01472

Species: Human

Expression System: HEK293

CXCL1 Protein, Human, Recombinant

TMPY-02868

Species: Human

Expression System: E. coli

CXCL1 Protein, Human, Recombinant (His & NusA)

TMPY-02180

Species: Human

Expression System: E. coli

CXCL1 Protein, Human, Recombinant (His & SUMO)

TMPY-02026

Species: Human

Expression System: E. coli

Cap8A Protein, S. aureus, Recombinant (His)

TMPH-03526

Species: Staphylococcus aureus

Expression System: in vitro E. coli expression system

CXCL2 Protein, Mouse, Recombinant

TMPJ-00011

Species: Mouse

Expression System: E. coli

TSPAN8 Protein, Human, Recombinant (His)

TMPY-03564

Species: Human

Expression System: HEK293

IL-24 Protein, Human, Recombinant (His)

TMPY-02087

Species: Human

Expression System: HEK293

CXCL9 Protein, Human, Recombinant

TMPY-02234

Species: Human

Expression System: E. coli

DKK1 Protein, Human, Recombinant (His)

TMPY-00775

Species: Human

Expression System: HEK293

DKK1 Protein, Mouse, Recombinant (His)

TMPY-04811

Species: Mouse

Expression System: HEK293

LRRC15 Protein, Human, Recombinant (hFc)

TMPY-04333

Species: Human

Expression System: HEK293

DKK1 Protein, Rhesus, Recombinant (N256Q, His)

TMPY-01174

Species: Rhesus

Expression System: HEK293

Glypican 3/GPC3 Protein, Human, Recombinant (His)

TMPY-01283

Species: Human

Expression System: HEK293

Glypican 3/GPC3 Protein, Mouse, Recombinant (His)

TMPY-00502

Species: Mouse

Expression System: Baculovirus-Insect Cells

FAP Protein, Human, Recombinant (His)

TMPY-02154

Species: Human

Expression System: HEK293

FAP Protein, Cynomolgus, Recombinant (His)

TMPY-04962

Species: Cynomolgus

Expression System: HEK293

FAP Protein, Human, Recombinant (His), Biotinylated

TMPY-04922

Species: Human

Expression System: HEK293

CD25/IL2R alpha Protein, Mouse, Recombinant (His)

TMPY-01923

Species: Mouse

Expression System: HEK293

CD25/IL2R alpha Protein, Rhesus, Recombinant (His & Avi), Biotinylated

TMPY-05644

Species: Rhesus

Expression System: HEK293

CD25/IL2R alpha Protein, Human, Recombinant (His)

TMPY-01103

Species: Human

Expression System: HEK293

CD25/IL2R alpha Protein, Human, Recombinant (His & Avi), Biotinylated

TMPY-05584

Species: Human

Expression System: HEK293

CD25/IL2R alpha Protein, Rat, Recombinant (His)

TMPY-05090

Species: Rat

Expression System: Baculovirus-Insect Cells

CD25/IL2R alpha Protein, Cynomolgus, Recombinant (His)

TMPY-03644

Species: Cynomolgus

Expression System: HEK293

CD25/IL2R alpha Protein, Cynomolgus, Recombinant

TMPY-03776

Species: Cynomolgus

Expression System: HEK293

IL-2 Protein, Mouse, Recombinant

TMPY-02788

Species: Mouse

Expression System: E. coli

IL-2 Protein, Rat, Recombinant

TMPY-02457

Species: Rat

Expression System: E. coli

AMIGO2 Protein, Mouse, Recombinant (His)

TMPK-01072

Species: Mouse

Expression System: HEK293

ABCB5 Protein, Human, Recombinant (Trx)

TMPJ-01145

Species: Human

Expression System: E. coli

HLA-A*02:01&B2M&MART-1 (ELAGIGILTV) Monomer Protein, Human, MHC (His & Avi)

TMPK-01469

Species: Human

Expression System: HEK293

HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Monomer Protein, Human, MHC (His & Avi)

TMPK-01441

Species: Human

Expression System: HEK293

AMIGO2 Protein, Cynomolgus, Recombinant (His)

TMPK-00660

Species: Cynomolgus

Expression System: HEK293

TSPAN8 Protein, Human, Recombinant (mFc)

TMPY-03675

Species: Human

Expression System: HEK293

HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Monomer Protein, Human, MHC (His & Avi), Biotinylated

TMPK-01447

Species: Human

Expression System: HEK293

HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Tetramer Protein, Human, MHC (His & Avi)

TMPK-01454

Species: Human

Expression System: HEK293

HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Monomer Protein, Human, MHC (His & Avi)

TMPK-01455

Species: Human

Expression System: HEK293

HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled

TMPK-01406

Species: Human

Expression System: HEK293

HLA-A*02:01&B2M&MART-1 (ELAGIGILTV) Tetramer Protein, Human, MHC (His & Avi)

TMPK-01468

Species: Human

Expression System: HEK293

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カタログ番号	製品名
L2192	Anti-Pancreatic Cancer Compound Library	2267 compounds
	A unique collection of 2267 pancreatic cancer related compounds can be used in HTS and HCS;
L8710	Cuproptosis Compound Library	411 compounds
	TargetMol’s Cuproptosis Compound Library is a collection of 411 compounds related to copper-dependent death that can be used to study its mechanism and related diseases.

ライブラリー

Anti-Pancreatic Cancer Compound Library

L2192

Compounds: 2267

Cuproptosis Compound Library

L8710

Compounds: 411