Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.
説明 | Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM. |
ターゲット&IC50 | MKLP2:1.35 μM, MKLP2:3.36 Μm(Ki) |
In vitro | Paprotrain-treated porcine oocytes suffer failure of nuclear maturation.?The number of oocytes arrested at early MI stage increase in a dose-dependent manner after KIF20A activity inhibition, while the percentage of oocytes that reach ATI and MII stages decrease after treatment[3]. |
別名 | (alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile |
分子量 | 245.28 |
分子式 | C16H11N3 |
CAS No. | 57046-73-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (407.70 mM)
You can also refer to dose conversion for different animals. 詳細
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Paprotrain 57046-73-8 Cytoskeletal Signaling Kinesin Inhibitor (alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile inhibit inhibitor