Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Phenylbiguanide (N-Phenylbiguanide) is a 5-HT3 receptor selective agonist(EC50 : 3.0±0.1 μM)
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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50 mg | 在庫あり | ¥ 7,000 | |||
100 mg | 在庫あり | ¥ 9,000 | |||
500 mg | 在庫あり | ¥ 20,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 10,000 |
説明 | Phenylbiguanide (N-Phenylbiguanide) is a 5-HT3 receptor selective agonist(EC50 : 3.0±0.1 μM) |
ターゲット&IC50 | 5-HT3:3 μM (EC50) |
In vivo | Phenylbiguanide (PBG) is a drug known to stimulate cardiopulmonary afferent C-fibres. PBG is injected into the right atrium of the heart in anaesthetised mice and mapped c-Fos expression within specific regions of the central nervous system. Intraatrial injection of PBG produces a reflex cardiorespiratory response including a pronounced bradycardia and a respiratory depression[1]. |
別名 | PBG, N-Phenylbiguanide, 1-Phenylbiguanide |
分子量 | 177.21 |
分子式 | C8H11N5 |
CAS No. | 102-02-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 150 mg/mL (846.45 mM)
You can also refer to dose conversion for different animals. 詳細
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Phenylbiguanide 102-02-3 GPCR/G Protein Neuroscience 5-HT Receptor 5-hydroxytryptamine Receptor inhibit PBG N-Phenylbiguanide Serotonin Receptor 1-Phenylbiguanide Inhibitor inhibitor