Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Pimethixene (Calmixen) is a highly potent 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as well as muscarinic M1 and M2 receptors antagonist(pKis of 7.63, 10.22, 10.44, 8.42, 10.14, 8.19, 7.54, 8.61 and 9.38, respectively).
説明 | Pimethixene (Calmixen) is a highly potent 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as well as muscarinic M1 and M2 receptors antagonist(pKis of 7.63, 10.22, 10.44, 8.42, 10.14, 8.19, 7.54, 8.61 and 9.38, respectively). |
ターゲット&IC50 | 5-HT2C receptor:8.42 (pki), M2 mAChR:9.38 (pki), D2 receptor:8.19 (pki), 5-HT1A receptor:7.63 (pki), DD4.4 receptor:7.54 (pki), 5-HT2A receptor:10.22 (pki), M1 receptor:8.61 (pki), H1 receptor:10.14 (pki), 5-HT2B receptor:10.44 (pki) |
別名 | Calmixen, Pimetixene |
分子量 | 293.43 |
分子式 | C19H19NS |
CAS No. | 314-03-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 18.33 mg/ml (62.48 mM)
You can also refer to dose conversion for different animals. 詳細
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Pimethixene 314-03-4 GPCR/G Protein Immunology/Inflammation Neuroscience 5-HT Receptor Dopamine Receptor Histamine Receptor AChR Calmixen Inhibitor Serotonin Receptor Pimetixene 5-hydroxytryptamine Receptor inhibit inhibitor