Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Quarfloxin (CX-3543) is a fluoroquinolone derivative with antineoplastic activity with IC50 values in the nanomolar range in neuroblastoma cells. Quarfloxin disrupts the interaction between the nucleolin protein and a G-quadruplex DNA structure in the ribosomal DNA template.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 28,000 | |||
5 mg | 在庫あり | ¥ 61,500 | |||
10 mg | 在庫あり | ¥ 98,500 | |||
25 mg | 在庫あり | ¥ 158,000 | |||
50 mg | 在庫あり | ¥ 222,500 | |||
100 mg | 在庫あり | ¥ 282,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 83,000 |
説明 | Quarfloxin (CX-3543) is a fluoroquinolone derivative with antineoplastic activity with IC50 values in the nanomolar range in neuroblastoma cells. Quarfloxin disrupts the interaction between the nucleolin protein and a G-quadruplex DNA structure in the ribosomal DNA template. |
In vitro | Quarfloxin effectively inhibits the growth of neuroblastoma cells in vitro. Quarfloxin and induces DNA damage, p53 signaling, cell death, and cell cycle arrest in neuroblastoma cell lines[1]. |
別名 | CX-3543 |
分子量 | 604.67 |
分子式 | C35H33FN6O3 |
CAS No. | 865311-47-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/ml (90.96 mM)
H2O: 1 mg/mL (1.65 mM), when pH is adjusted to 5 with 0.1 M HCl. Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Quarfloxin 865311-47-3 Cell Cycle/Checkpoint DNA Damage/DNA Repair DNA/RNA Synthesis inhibit Inhibitor CX-3543 CX3543 CX 3543 inhibitor