Powder: -20°C for 3 years | In solvent: -80°C for 1 year
RAF709 is a novel Raf kinase inhibitor with IC50s of 0.5 and 1.8 nM for c-Raf and b-Raf, respectively.
説明 | RAF709 is a novel Raf kinase inhibitor with IC50s of 0.5 and 1.8 nM for c-Raf and b-Raf, respectively. |
ターゲット&IC50 | B-Raf:1.8 nM, C-Raf:0.5 nM |
In vitro | The invention provides compounds (e.g., RAF709) that inhibit Raf kinases, and are accordingly useful for treating certain disorders associated with excessive Raf kinase activity, including cell proliferation disorders such as cancers[1]. |
分子量 | 542.55 |
分子式 | C28H29F3N4O4 |
CAS No. | 1628838-42-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 91 mg/mL(167.8 mM)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
RAF709 1628838-42-5 MAPK Raf Inhibitor inhibit RAF-709 Raf kinases RAF 709 inhibitor