Powder: -20°C for 3 years | In solvent: -80°C for 1 year
RO8994 is a highly effective and specific inhibitor of spiroindolinone small-molecule MDM2, with IC50 of 20 nM (MTT proliferation assays) and 5 nM (HTRF binding assays).
説明 | RO8994 is a highly effective and specific inhibitor of spiroindolinone small-molecule MDM2, with IC50 of 20 nM (MTT proliferation assays) and 5 nM (HTRF binding assays). |
ターゲット&IC50 | MDM2:20 nM |
分子量 | 613.51 |
分子式 | C31H31Cl2FN4O4 |
CAS No. | 1309684-94-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (81.5 mM)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
RO8994 1309684-94-3 Apoptosis Ubiquitination p53 E1/E2/E3 Enzyme Mdm2 E2 conjugating enzyme MDM-2/p53 Ubiquitin conjugating enzyme RO 8994 Ubiquitin activating enzyme E3 ligating enzyme inhibit Inhibitor E1 activating enzyme RO-8994 Ubiquitin ligase inhibitor