Powder: -20°C for 3 years | In solvent: -80°C for 1 year
RU-SKI 43 is a potent and selective hedgehog acyltransferase (Hhat) inhibitor with an IC50 of 850 nM.RU-SKI 43 has anticancer activity and is a potential compound for the treatment of lung adenocarcinomas.RU-SKI 43 reduces Gli-1 activation through smoothing-independent non-canonical signalling and inhibits Akt and mTOR pathway activity.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 10,500 | |||
5 mg | 在庫あり | ¥ 25,500 | |||
10 mg | 在庫あり | ¥ 36,000 | |||
25 mg | 在庫あり | ¥ 86,000 | |||
50 mg | 在庫あり | ¥ 128,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 27,000 |
ターゲット&IC50 | Hhat:850 nM, [125I]-iodo-palmitoylCoA:6.9 μM(Ki), Shh:7.4 μM(Ki) |
別名 | RUSKI 43 |
分子量 | 386.55 |
分子式 | C22H30N2O2S |
CAS No. | 1043797-53-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
RU-SKI 43 1043797-53-0 GPCR/G Protein Metabolism Stem Cells Hedgehog/Smoothened Acyltransferase RUSKI-43 RUSKI43 RUSKI 43 Inhibitor inhibitor inhibit