Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Rabeprazole (LY307640) is an H+/K+-ATPase inhibitor that inhibits cell proliferation in gastric epithelial cells by targeting STAT3-mediated glycolysis and can be used in the study of gastric ulcers.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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5 mg | 在庫あり | ¥ 7,500 | |||
10 mg | 在庫あり | ¥ 11,000 | |||
25 mg | 在庫あり | ¥ 18,000 | |||
50 mg | 在庫あり | ¥ 26,000 |
説明 | Rabeprazole (LY307640) is an H+/K+-ATPase inhibitor that inhibits cell proliferation in gastric epithelial cells by targeting STAT3-mediated glycolysis and can be used in the study of gastric ulcers. |
ターゲット&IC50 | UNH:0.3 μM (IC50) |
In vitro | Rabeprazole was administered to three gastric cancer cell lines, KATO III, MKN-28, and MKN-45, at a dosage of 0.2 mM under acidic conditions for 16 hours. The results showed that rabeprazole exerted a strong inhibitory effect on the proliferation of gastric cancer cells[2]. |
In vivo | The results of rabeprazole (10 mg/kg; oral administration; every 48 hours for 18 weeks) showed significantly lower serum calcium levels compared to the vehicle-treated group in Swiss albino mice[3]. |
別名 | LY307640 |
分子量 | 359.44 |
分子式 | C18H21N3O3S |
CAS No. | 117976-89-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 5 mg/mL (13.91 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Rabeprazole 117976-89-3 JAK/STAT signaling Membrane transporter/Ion channel Stem Cells STAT Potassium Channel LY307640 Inhibitor inhibitor inhibit