Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Rhein (NSC 38629) is an anthraquinone compound extracted from Polygonaceae Rheum Officinale with anti-inflammation and antitumor activities.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
100 mg | 在庫あり | ¥ 11,500 | |||
200 mg | 在庫あり | ¥ 18,500 | |||
500 mg | 在庫あり | ¥ 36,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 11,500 |
説明 | Rhein (NSC 38629) is an anthraquinone compound extracted from Polygonaceae Rheum Officinale with anti-inflammation and antitumor activities. |
In vitro | In diabetic nephropathy-afflicted db/db mice, Rhein effectively ameliorates diabetic renal lesions and mitigates hyperlipidemia by reducing plasma cholesterol (Chol), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), ApoE, and renal tissue transforming growth factor-β1 (TGF-β1). |
In vivo | In chondrocytes, Rhein (35 µM) effectively inhibits the synthesis of IL-1β in human osteoarthritis synovium and exerts effects in cartilage by reducing the amount of IL-1R and inhibiting the production of NO induced by IL-1β. Additionally, Rhein is capable of inducing apoptosis in acute promyelocytic leukemia cells (HL-60). |
植物由来 |
別名 | Rheinic Acid, Monorhein, NSC 38629, Rheic Acid, Rhubarb yellow |
分子量 | 284.22 |
分子式 | C15H8O6 |
CAS No. | 478-43-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 5.45 mg/mL (19.19 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Rhein 478-43-3 Autophagy Immunology/Inflammation Metabolism Microbiology/Virology NF-Κb Reactive Oxygen Species Antibacterial Rheinic Acid Bacterial Inhibitor Monorhein NSC 38629 NSC-38629 Rheic Acid Rhubarb yellow inhibit NSC38629 inhibitor