Powder: -20°C for 3 years | In solvent: -80°C for 1 year
S-23 ((S)-3-(4-chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide) is an oral selective androgen receptor modulator (SARM) with a Ki of 1.7 nM. S-23 increases prostate, seminal vesicle, and levator ani muscle weights in castrated rats.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
5 mg | 在庫あり | ¥ 9,000 | |||
10 mg | 在庫あり | ¥ 15,000 | |||
25 mg | 在庫あり | ¥ 29,500 | |||
50 mg | 在庫あり | ¥ 45,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 10,000 |
説明 | S-23 ((S)-3-(4-chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide) is an oral selective androgen receptor modulator (SARM) with a Ki of 1.7 nM. S-23 increases prostate, seminal vesicle, and levator ani muscle weights in castrated rats. |
ターゲット&IC50 | Androgen receptor:1.7 nM(Ki) |
In vitro | Administration of 10 nM S-23 induces AR-mediated transcriptional activation in CV-1 cells [2]. |
In vivo | Administration of S-23 to castrated animals increases the weights of the androgen-dependent organ dose-dependently with the ED50s of S-23 in the prostate and levator ani muscle of 0.43 and 0.079 mg/d, respectively[2]. |
別名 | (S)-3-(4-chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide, S23 |
分子量 | 416.75 |
分子式 | C18H13ClF4N2O3 |
CAS No. | 1010396-29-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (119.98 mM)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
S-23 1010396-29-8 Endocrinology/Hormones Androgen Receptor activation levator castrated S 23 ani Inhibitor (S)-3-(4-chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide vesicle cells transcriptional muscle prostate S23 seminal CV-1 inhibit inhibitor