Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SNX0723 is a potent Hsp90 Inhibitor with anti-Plasmodium activity. SNX0723 shows high binding affinity for HsHsp90 and PfHsp90 with Kis of 4.4 and 47 nM, respectively. SNX0723 inhibits liver-stage P. berghei ANKA parasites with the EC50 of 3.3 μM.
説明 | SNX0723 is a potent Hsp90 Inhibitor with anti-Plasmodium activity. SNX0723 shows high binding affinity for HsHsp90 and PfHsp90 with Kis of 4.4 and 47 nM, respectively. SNX0723 inhibits liver-stage P. berghei ANKA parasites with the EC50 of 3.3 μM. |
In vitro | SNX0723 inhibits P. falciparum Dd2 blood-stage parasites and P. berghei ANKA liver-stage parasites, EC50 are 7.4μM and 6.5μM, respectively[1]. |
別名 | SNX 0723, SNX- 0723 |
分子量 | 399.46 |
分子式 | C22H26FN3O3 |
CAS No. | 1073969-18-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 18.9 mg/mL (47.3 mM), Sonication and heating to 60℃ are recommended.
You can also refer to dose conversion for different animals. 詳細
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SNX0723 1073969-18-2 Cytoskeletal Signaling Metabolism HSP SNX-0723 SNX 0723 SNX- 0723 Inhibitor inhibitor inhibit