Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SR59230A is a potent, selective antagonist of β3-adrenergic receptor(β3, β1, and β2 receptors with IC50s of 40, 408, and 648 nM , respectively).
説明 | SR59230A is a potent, selective antagonist of β3-adrenergic receptor(β3, β1, and β2 receptors with IC50s of 40, 408, and 648 nM , respectively). |
ターゲット&IC50 | β1-adrenoceptor:408 nM , β3-adrenoceptor:40 nM , β2-adrenoceptor:648 nM |
In vitro | The specific antagonism of β3-AR by SR59230A inhibits NB growth and tumor progression, by switching from stemness to cell differentiation both in vivo and in vitro through the specific blockade of SK2/S1P2 signaling[1]. |
分子量 | 415.48 |
分子式 | C23H29NO6 |
CAS No. | 174689-39-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 30 mg/mL (72.21 mM)
You can also refer to dose conversion for different animals. 詳細
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SR59230A 174689-39-5 GPCR/G Protein Neuroscience Adrenergic Receptor hyperthermia adrenoceptor adrenergic Beta Receptor inhibit hypothermia receptor Inhibitor SR-59230A inhibitor