Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Sepantronium bromide (YM155) is a small-molecule proapoptotic agent with potential antineoplastic activity.
説明 | Sepantronium bromide (YM155) is a small-molecule proapoptotic agent with potential antineoplastic activity. |
ターゲット&IC50 | Survivin:0.54 nM |
キナーゼ試験 | Promoter-luciferase reporter assay: A 2,767-bp sequence of human survivin gene promoter is isolated from human genomic DNA by PCR using Pyrobest polymerase and the following primers: 5 |
細胞研究 | Cells are seeded in 96-well plates at a density of 5-40 × 103. YM155 is dissolved in DMSO and added to cells for 48 hours. Then the cell count is determined by sulforhodamine B assay. (Only for Reference) |
別名 | YM155 |
分子量 | 443.26 |
分子式 | C20H19BrN4O3 |
CAS No. | 781661-94-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 82 mg/mL (185 mM)
Ethanol: 6 mg/mL (13.53 mM)
DMSO: 4.43 mg/mL (10 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Sepantronium bromide 781661-94-7 Apoptosis Autophagy Survivin inhibit Inhibitor YM-155 Sepantronium YM155 YM 155 Sepantronium Bromide inhibitor