Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solabegron (GW 427353) is a selective agonist of β3-adrenergic receptor, stimulating cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR(EC50 : 22 nM). It is used for treatment of overactive bladder and irritable bowel syndrome.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 20,500 | |||
5 mg | 在庫あり | ¥ 64,000 | |||
10 mg | 在庫あり | ¥ 104,500 | |||
25 mg | 在庫あり | ¥ 190,000 | |||
50 mg | 在庫あり | ¥ 257,000 | |||
100 mg | 在庫あり | ¥ 342,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 68,500 |
説明 | Solabegron (GW 427353) is a selective agonist of β3-adrenergic receptor, stimulating cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR(EC50 : 22 nM). It is used for treatment of overactive bladder and irritable bowel syndrome. |
ターゲット&IC50 | β3-adrenoceptor:(EC50)22 Nm |
In vivo | Solabegron(3 mg/kg i.v.)evokes an increase in micturition volume threshold that prevented the acetic acid-evoked decreases in dogs. |
別名 | GW 427353 |
分子量 | 410.89 |
分子式 | C23H23ClN2O3 |
CAS No. | 252920-94-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 250 mg/mL (608.44 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Solabegron 252920-94-8 GPCR/G Protein Neuroscience Adrenergic Receptor inhibit Inhibitor GW 427353 GW427353 Beta Receptor GW-427353 inhibitor