Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Sonepiprazole (PNU-101387G) is a chemical compound known for its selective antagonistic properties toward D4 dopamine receptors, exhibiting dissociation constants (Kis) of 3.6 nM and 10.1 nM for rat D4 (rD4) and human D4.2 (hD4.2) dopamine receptors, respectively. Furthermore, it shows significantly less affinity for rat D2 (rD2) dopamine and Histamine-H1 receptors with Kis of 5147 nM and 7430 nM, respectively.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 9,000 | |||
5 mg | 在庫あり | ¥ 20,500 | |||
10 mg | 在庫あり | ¥ 33,000 | |||
25 mg | 在庫あり | ¥ 73,000 | |||
50 mg | 在庫あり | ¥ 123,500 | |||
100 mg | 在庫あり | ¥ 178,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 25,000 |
説明 | Sonepiprazole (PNU-101387G) is a chemical compound known for its selective antagonistic properties toward D4 dopamine receptors, exhibiting dissociation constants (Kis) of 3.6 nM and 10.1 nM for rat D4 (rD4) and human D4.2 (hD4.2) dopamine receptors, respectively. Furthermore, it shows significantly less affinity for rat D2 (rD2) dopamine and Histamine-H1 receptors with Kis of 5147 nM and 7430 nM, respectively. |
ターゲット&IC50 | H1 receptor:7430 nM (Ki), D4 receptor (rat):3.6 nM (Ki), D4 receptor (human):10.1 nM (Ki), D2 receptor (rat):5147 nM (Ki) |
分子量 | 401.52 |
分子式 | C21H27N3O3S |
CAS No. | 170858-33-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/ml (149.43 mM)
You can also refer to dose conversion for different animals. 詳細
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Sonepiprazole 170858-33-0 GPCR/G Protein Neuroscience Dopamine Receptor inhibit U-101387G PNU-101387G Inhibitor inhibitor