keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
KIF18A-IN-2 is an inhibitor of mitotic kinesin Kif18A with IC50 of 28 nM and can be used in studies about chromosomal instability-associated vulnerabilities.
説明 | KIF18A-IN-2 is an inhibitor of mitotic kinesin Kif18A with IC50 of 28 nM and can be used in studies about chromosomal instability-associated vulnerabilities. |
In vivo | In Female athymic nude mice injected with human OVCAR-3 HGSOC cells, KIF18A-IN-2 (100 mg/kg; i.p.) exhibits a significant and sustained pharmacodynamic response and increases the number of mitotic cells (pH3 positive cells) in tumor tissues[1]. |
分子量 | 534.69 |
分子式 | C25H34N4O5S2 |
CAS No. | 2600559-20-2 |
keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (102.86 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
KIF18A-IN-2 2600559-20-2 Cytoskeletal Signaling Microtubule Associated Inhibitor Mitotic Microtubule Cancer OVCAR-3 KIF18A Microtubule/Tubulin KIF18A IN 2 inhibit KIF18AIN2 Tubulin inhibitor