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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T7879 | TASP0415914 | Akt , PI3K | |
TASP0415914 is an orally potent inhibitor of phosphoinositide 3-kinase γ (PI3Kγ). T | |||
T6928 | Pantoprazole | SKF96022,BY1023 | Apoptosis , Proton pump , Autophagy |
Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease. | |||
T0161 | Pantoprazole Sodium Hydrate | SKF96022 sodium hydrate,BY1023 (sodium hydrate),SKF96022 (sodium hydrate) | Apoptosis , Potassium Channel , Proton pump , Autophagy |
Pantoprazole Sodium Hydrate (BY1023 (sodium hydrate)) is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease. | |||
T6929 | Pantoprazole sodium | Pantecta,SKF96022 sodium,SKF96022 (sodium),BY1023 (sodium),BY-1023 sodium,Pantoloc | Apoptosis , Others , Proton pump , HIF , Autophagy |
Pantoprazole sodium (Pantecta) is the sodium salt form of a substituted benzimidazole with proton pump inhibitor activity. Pantoprazole sodium is a lipophilic, weak base that crosses the parietal cell membrane and enters... | |||
T20075 | Sodium dodecyl sulfate | Laurylsulfuric acid sodium salt,NSC 402488,Anticerumen,NSC-402488,NSC402488,Natrium laurylsulfuricum,Sodium dodecylsulfate,Sodium lauryl sulfate | Others |
Sodium dodecyl sulfate(Sodium lauryl sulfate) is a pharmaceutical excipient that is biologically inactive and improves the stability, solubility and processability of pharmaceutical preparations. | |||
T19853 | Dimethoxycurcumin | Veratrylcurcuminoid | Others |
Dimethoxycurcumin (Veratrylcurcuminoid) is an analog of curcumin with more metabolical stability. Dimethoxycurcumin induces epigenetic changes in leukemia cells and the expression of promoter methylated genes. | |||
T28973 | TIBI | Others | |
TIBI is an ATP-competitive Rio1 inhibitor that acts in a similar manner to fungamycin and enhances the thermal stability of the enzyme. | |||
T10002 | (E)-Crotylbarbital | Kalypnon | Others |
(E)-Crotylbarbital (Kalypnon), an isomer of Crotylbarbital, is a barbiturate derivative that has sedative, hypnotic, and anticonvulsant effects. (E)-Crotylbarbital can be used in studies to promote mental stability and s... | |||
T19609 | HP-β-CD | Hydroxypropyl-β-cyclodextrin,Hydroxypropyl betadex | Others |
HP-β-CD (HP-β-CD) is a widely used drug delivery vehicle to improve stability and bioavailability. | |||
T9058 | Bisphenoxyethanolfluorene | Others | |
Bisphenoxyethanolfluorene a high stability of the new type of organic chemical raw materials, mainly used for synthesis of heat resistance, excellent transparency and high refractive index of polymer monomer | |||
T6705 | TIC10 Isomer | ONC201 isomer,TIC10 Analogue | Others |
TIC10 Isomer (ONC201 isomer) is an isomer of TIC10, which inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improv... | |||
T29059 | UMK57 | UMK 57,UMK-57 | Kinesin |
UMK57 is a CENP-Ei and MCAK enhancer, selectively promoting k-MT attachment error correction to inhibit chromosome missegregation of small molecule compounds, and can improve chromosome separation conservation by disrupt... | |||
T15409 | GNF179 | Parasite | |
GNF179 is an optimized 8,8-dimethyl IP analog. It exhibited the potency(4.8 nM against the multidrug resistant strain W2) in vitro metabolic stability and in vivo oral bioavailability. | |||
T73040 | CYP1B1-IN-4 | P450 | |
CYP1B1-IN-4, a 2,4-diarylthiazole compound, exhibits selective inhibition of CYP1B1 (IC50=0.2 nM), demonstrating minimal cytotoxicity and high stability in human and rat liver microsomes [1]. | |||
T11717 | JHU395 | Apoptosis | |
T9698 | UC2288 | Mdm2 , p53 | |
UC2288 is a relatively selective p21 attenuator which is synthesized based Sorafenib. UC2288 attenuates p21 protein levels with minimal effect on p21 protein stability. | |||
T21673 | N-Isopropylnoratropine | Others | |
N-Isopropylnoratropine is a noratropine derivative and an intermediate in the production of ipratropium, an atropine-like bronchodilator drug via an anticholinergic pathway. N-Isopropylnoratropine is used to examine the ... | |||
T0901 | Chlorobutanol | Chlortran,Chloretone,YM-57158,Chlorbutol,Chloreton | Antibacterial , Antibiotic , Antifungal |
Chlorobutanol (Chlortran) is a chemical preservative, sedative hypnotic and weak local anaesthetic. It has Antibacterial and Antifungal properties. Chlorobutanol is typically used at a concentration of 0.5% where it lend... | |||
T3622 | CP-640186 hydrochloride | CP 640186 HCl | Acetyl-CoA Carboxylase |
CP-640186 hydrochloride (CP 640186 HCl) is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor, including rat liver ACC1 (IC50: 53 nM) and rat skeletal muscle ACC2 (IC50: 61 nM); with higher metabolic stabilit... | |||
T7001 | TIC10 | ONC-201 | Apoptosis , TNF |
TIC10 (ONC-201) inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improved pharmacokinetics. Phase 1/2. | |||
T7423 | Diquafosol tetrasodium | INS365 | P2Y Receptor |
Diquafosol Tetrasodium is a P2Y2 receptor agonist that stimulates the secretion of mucins from ocular tissues Diquafosol tetrasodium (INS365) improves tear film stability and visual function, as a topical treatment of dr... | |||
T8670 | Fmoc-L-2-cyanophenylalanine | Others | |
fmoc-L-2-cyanophenylalanine is a derivative of the amino acid phenylalanine. Due to its excellent reactivity and stability, it is widely used in peptide synthesis, as well as in the synthesis of a variety of other biolog... | |||
T5593 | L-Alanyl-L-glutamine | Ala-Gln | Others , Endogenous Metabolite |
L-Alanyl-L-glutamine (Ala-Gln), a dipeptide composed of alanine and Gln, is an alternative supplement to L-glutamine in the production of biopharmaceuticals with better solubility and stability than glutamine (Gln). | |||
T60084 | FINO2 | Ferroptosis | |
FINO2 is a potent ferroptosis-inducing compound that inhibits GPX4 activity. It functions as a stable oxidant, effectively oxidizing ferrous iron and demonstrating stability across varying pH levels. Furthermore, FINO2 i... | |||
T38651 | Lauryl maltose neopentyl glycol | LMNG | |
Lauryl maltose neopentyl glycol (LMNG) is a detergent that solubilizes and stabilizes membrane proteins. lauryl maltose neopentyl glycol extracts intact membrane proteins from membranes, thereby improving the stability o... | |||
T20870 | IR-820 | IR 820,IR820,New Indocyanine Green | |
IR-820 (New Indocyanine Green) is a near-infrared dye with better stability, good color rendering, and excellent fluorescence penetration. IR-820 is an infrared blood pool contrast agent used to detect and quantify disea... | |||
T9394 | CHIKV-IN-2 | Dehydrogenase | |
CHIKV-IN-2, a chemical compound, exhibits potent inhibitory activity against the enzyme Dihydroorotate Dehydrogenase (DHODH), crucial for pyrimidine synthesis affecting various viruses' replication. It serves as an effec... | |||
T22530 | 6-Chloromelatonin | Melatonin Receptor , Dopamine Receptor | |
6-Chloromelatonin is a potent melatonin receptor agonist, a 5-methoxyindole compound that competes for the same presynaptic melatonin receptor sites in the rabbit retina and inhibits the calcium-dependent release of [3H]... | |||
T0932 | Cefixime | FK-027,Cefspan,Cefiximum,Cephoral,FR-17027,CL-284635 | Antibacterial , Antibiotic |
Cefixime (FR-17027) is a broad-spectrum, third-generation cephalosporin antibiotic derived semisynthetically from the marine fungus Cephalosporium acremonium with antibacterial activity. As does penicillin, the beta-lact... | |||
T8947 | Dasiglucagon acetate | dasiglucagon acetate(1544300-84-6 free base) | Others |
Dasiglucagon acetate is a novel glucagon analog for diabetic hypoglycemia therapy. Dasiglucagon acetate has demonstrated established solubility and stability in an aqueous formulation. Pharmacokinetics studies have shown... | |||
T1224 | Cefuroxime sodium | Anaptivan,Cefuroxime sodium salt,Biociclin | Antibacterial , Antibiotic |
Cefuroxime Sodium is the sodium salt form of cefuroxime and a semi-synthetic, broad-spectrum, beta-lactamase resistant, second-generation cephalosporin antibiotic with bactericidal activity. Cefuroxime sodium (Cefuroxime... | |||
T67831 | HIF-2α agonist 2 | HIF/HIF Prolyl-Hydroxylase , HIF | |
HIF-2α agonist 2 is an HIF-2α agonist with an EC50 value of 1.68 μM for HIF-2α. HIF-2α agonist 2 can promote the stability of the ARNT A/B ring in the 3z structure of HIF-2a-ARNT complex without cytotoxicity to 786-o-Reh... | |||
T74485 | STC314 | Others | |
STC314 is an anti-infective agent that reverses organ damage caused by excessive immune response by neutralizing extracellular histones and neutrophil trapping networks, and can be used in the study of sepsis and acute r... | |||
T60877 | Mtb ATP synthase-IN-1 | ||
Mtb ATP synthase-IN-1 (compound 6ab) can be used in anti-mycobacterium research. Mtb ATP synthase-IN-1 shoys low cytotoxicity (Vero IC 50 > 64 μg/mL) and acceptable oral bioavailability that has good metabolic stability.... | |||
T6284 | Onalespib | AT13387,Onalespib (AT13387) | HSP |
Onalespib (AT13387) is a synthetic, orally bioavailable, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. Onalespib selectively binds to Hsp90, thereby inhibiting its chap... | |||
T61268 | Vutiglabridin | HSG4112 | Phosphatase |
Vutiglabridin (HSG4112) is a novel and safe modulator of PON2, a racemic compound. vutiglabridin is an optimized structural analogue of Glabridin and is superior to Glabridin in terms of weight loss and chemical stabilit... | |||
T29244 | (+)-Carbovir | L-Carbovir | |
(+)-Carbovir is a nucleoside analog with increased chemical stability and increased metabolic stability. | |||
T31523 | Diptoindonesin G | ||
Diptoindonesin G is an ERß stabilizer that regulates the stability of ERα and ERß by targeting CHIP E3 ubiquitin ligase. Diptoindonesin G could significantly increase the protein stability of ERß, and reduce the protein ... | |||
T10845 | CMK | Others | |
CMK, an RSK2 kinase inhibitor, shows similar potency but less chemical stability compared with FMK. | |||
T13548 | AN7973 | Others | |
AN7973 blocks intracellular parasite development and inhibits Cryptosporidium growth. It is orally active, possesses favorable safety, stability, and PK parameters. | |||
T70091 | IACS-4759 | ||
IACS-4759 is a novel potent and selective MTH1 inhibitor with excellent cell permeability and good metabolic stability in microsomes. | |||
T38707 | MPC-0767 | ||
MPC-0767, a potent, selective, and orally active hsp90 inhibitor, is the L-alanine ester prodrug of MPC-3100, exhibiting enhanced chemical stability. | |||
T32242 | IWP-051 | IWP051 | |
IWP-051 is a potent, orally active sGC stimulator (EC50 = 290nM). IWP-051 showed >99% plasma protein binding, high metabolic stability, high permeability, and no efflux in a Caco-2 model of intestinal absorption. IWP-... | |||
T39680 | Diflomotecan | BN 80915 | |
Diflomotecan (BN 80915) is a potent, orally active topoisomerase I inhibitor that displays enhanced plasma stability and superior preclinical anti-tumor activity relative to other established compounds. | |||
T29077 | Urolinin | nWWK-Tyr(3-NO2)-Abu | |
Urolinin is a linear peptidic Urotensin-II Receptor Agonist with low nanomolar potency as well as improved metabolic stability. Urolinin is a hexameric UIIR agonist with an EC50 of 4.75 nM and a metabolic stability of 13... | |||
T19773 | Diethyl bipy55'DC | ||
Diethyl bipy55'DC inhibits CP4H activity in cultured cells. The stability of collagen relies on post-translational modifications, the most prevalent being the hydroxylation of collagen strands by collagen prolyl 4-hydrox... | |||
T31174 | DABA | diaminobenzoic acid | |
DABA (diaminobenzoic acid) can react with all aldehydes in the form of RCH(2)CHO, has the high serum stability of oligomers, and will develop new nanomaterials in biotechnology and biomedical applications. | |||
T23596 | A-933548 | A933548,A 933548 | |
A-933548 is a potent Calpain inhibitor. A-933548 features enhanced selectivity versus related cysteine protease cathepsins, favorable microsomal stability, and efficacy in cellular assays. | |||
T11445 | GNF179 (Metabolite) | GNF179 Metabolite | Others |
GNF179 Metabolite, the derivative of GNF179—an optimized 8,8-dimethyl IP analog—demonstrates significant potency (4.8 nM against the multidrug-resistant W2 strain) alongside in vitro metabolic stability and in vivo oral ... | |||
T83187 | AChE-IN-41 | ||
AChE-IN-41 (Compound 2), a Galantamine-Memantine hybrid, possesses cholinesterase inhibitory capabilities. This compound demonstrates enhanced plasma stability and similar microsomal stability in vitro but has a reduced ... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T5080 | Spermidine trihydrochloride | Spermidine hydrochloride,4-Azaoctamethylenediamine trihydrochloride | NMDAR , Autophagy |
Spermidine trihydrochloride (4-Azaoctamethylenediamine trihydrochloride), a natural polyamine, is a novel autophagy inducer and negatively modulates N-methyl-d-aspartate (NMDA). | |||
T4893 | Spermidine | N-(3-Aminopropyl)-1,4-diaminobutane,N-(4-Aminobutyl)-1,3-diaminopropane | Endogenous Metabolite |
Spermidine (N-(3-Aminopropyl)-1,4-diaminobutane) inhibits NOS1 (nNOS). Spermidine binds and precipitates DNA and may be used for purification of DNA binding proteins. Spermidine activates PNK (polynucleotide kinase T4). ... | |||
T4925 | Thiamine monophosphate chloride (dihydrate) | Thiamine monophosphate chloride dihydrat,Aneurine monophosphate chloride | Others , Endogenous Metabolite |
Thiamine monophosphate chloride dihydrate (Aneurine monophosphate chloride) is a compound used in the screening of ligands that promote protein stability | |||
T4S2014 | 5,15-Diacetyl-3-benzoyllathyrol | Euphorbia factor L3 | Others |
1. 5,15-Diacetyl-3-benzoyllathyrol (Euphorbia factor L3) is a melanine production inhibitor, excellent in inhibiting pigment stagnation and improving the discoloration of the skin or freckles, has excellent stability. | |||
T4A2456 | Gamabufotalin | Gamabufagin | COX |
1. Gamabufotalin (Gamabufagin) , a major bufadienolide of Chansu, has been used for treatment of COX-2-mediated diseases and cancer therapy due to its desirable metabolic stability and less adverse effect. | |||
T2S1840 | Rebaudioside D | Others | |
Rebaudioside D is a potential sweetener. Rebaudioside D shows similar stability when exposed to simulate stomach and small intestine fluids, with susceptibility to hydrolytic degradation by enteric bacteria collected fro... | |||
T8160 | EGCG Octaacetate | Others , Antibacterial | |
EGCG Octaacetate, a prodrug of EGCG, is utilized to enhance the stability and bioavailability of EGCG in vivo. It has high efficacy, bioavailability, anti-oxidation, and anti-angiogenesis capacities. | |||
TN1608 | (-)-Epigallocatechin-3-(3''-O-methyl) gallate | (-)-EGCG-3''-O-ME | Antioxidant , Antibacterial |
(-)-Epigallocatechin-3-(3''-O-methyl) gallate ((-)-EGCG-3''-O-ME) is a natural product isolated from tea leaves with strong antioxidant, cytotoxic and antibacterial activity, which enhances the adhesive stability of etch... | |||
TN1275 | P-Hydroxyphenethyl anisate | 4-Hydroxyphenethylanisate | Others |
p-Hydroxyphenethyl anisate (4-Hydroxyphenethylanisate), a natural product from Notopterygium forbe-siiBoiss, is a novel polymeric sustained-release material that, after block copolymerization with AAPBA, produces nanopar... | |||
T14862 | Caprylic/Capric Triglyceride | Others | |
Caprylic/Capric Triglyceride, a compound consisting of triglycerides and esters derived from fractionated vegetable oil, and fatty acids from coconut and palm kernel oils, serves as a food additive and is utilized in cos... | |||
T5669 | Citric acid monohydrate | Others | |
Citric Acid Monohydrate is a tricarboxylic acid found in citrus fruits. Citric acid is used as an excipient in pharmaceutical preparations due to its antioxidant properties. It maintains stability of active ingredients a... | |||
T8733 | Antrodin A | camphorataanhydride A | Others |
Antrodin A (camphorataanhydride A) (AdA) is one of the main active ingredients in the solid-state fermented A. camphorata mycelium. It protects the liver from alcohol damage by improving the antioxidant and anti-inflamma... | |||
T37520 | DL-Glutamic acid | ||
DL-Glutamic acid, the conjugate acid of Glutamic acid, serves as a crucial metabolite. In comparison to the α and β polymorphs of L-Glutamic acid's second phase, DL-Glutamic acid exhibits enhanced stability[1]. | |||
T83725 | Nigerose | Sakebiose | |
Nigerose, a disaccharide identified in Acremonium, effectively maintains stability in HL-60 cells post-cryopreservation by preventing elevations in malondialdehyde (MDA) and reactive oxygen species (ROS) levels, and inhi... | |||
T80950 | Tricetin 7-O-glucoside | ||
Chemical Compound 77298-67-0 exhibits high thermal stability and outstanding resistance to both corrosion and oxidation, suitable for extreme environmental conditions. Its melting point lies above 3500°C. The compound de... | |||
T37770 | Taurohyodeoxycholic acid | ||
Taurohyodeoxycholic acid (THDCA) is a taurine-conjugated form of the secondary bile acid hyodeoxycholic acid .1THDCA decreases the size and weight of human gallstonesin vitro. It increases bile flow, biliary cholesterol ... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-03425 | Tau Protein, Human, Recombinant (His) | Human | E. coli |
MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are... | |||
TMPH-01653 | MLANA Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage ... | |||
TMPH-01652 | MLANA Protein, Human, Recombinant (B2M & His) | Human | E. coli |
Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage ... | |||
TMPH-02840 | PLOD2 Protein, Mouse, Recombinant (E. coli, His & Myc) | Mouse | E. coli |
Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-link... | |||
TMPH-01879 | PARP11 Protein, Human, Recombinant (His) | Human | E. coli |
Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins. Plays a role in nuclear envelope stability and nuclear remodeling during spermiogenesis. PARP11 Protein, Human, Recombinant (His) is exp... | |||
TMPY-04073 | MRPL44 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
MRPL44 (Mitochondrial Ribosomal Protein L44) is a Protein Coding gene. MRPL44 encodes a protein in the large subunit of the mitochondrial ribosome and is suggested to locate near the tunnel exit of the yeast mitochondria... | |||
TMPH-02839 | PLOD2 Protein, Mouse, Recombinant (His & Myc) | Mouse | Baculovirus Insect Cells |
Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-link... | |||
TMPH-03713 | ELAVL4 Protein, Xenopus tropicalis, Recombinant (His) | Xenopus tropicalis | E. coli |
RNA-binding protein that is involved in the post-transcriptional regulation of mRNAs. Plays a role in the regulation of mRNA stability, alternative splicing and translation. Binds to AU-rich element (ARE) sequences in th... | |||
TMPH-03748 | KAT14 Protein, Human, Recombinant (His) | Human | E. coli |
Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. May function as a scaffold for the ATAC complex to promote ATAC complex stability. Has also weak histone acetyltrans... | |||
TMPH-01979 | SFTPB Protein, Human, Recombinant | Human | P. pastoris (Yeast) |
Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearl... | |||
TMPH-01257 | Dystonin Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and musc... | |||
TMPH-01256 | Dystonin Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and musc... | |||
TMPH-03334 | Mitofilin Protein, Rat, Recombinant (His) | Rat | E. coli |
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to ... | |||
TMPH-03375 | Stathmin-2 Protein, Rat, Recombinant (His) | Rat | E. coli |
Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in cortical neurons. In the developing brain, negatively regulates the rate of exit from ... | |||
TMPH-02317 | YTHDF1 Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and regulates their stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stabi... | |||
TMPH-03193 | Alba Protein, Pyrococcus furiosus, Recombinant (His & SUMO) | Pyrococcus furiosus | E. coli |
Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DN... | |||
TMPH-00479 | Angiopoietin-1 Protein, Canine, Recombinant (His) | Canine | Baculovirus Insect Cells |
Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal i... | |||
TMPH-01322 | FANCC Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG... | |||
TMPK-01324 | S100A9 Protein, Canine, Recombinant (His) | Canine | E. coli |
S100A8 and S100A9 (also known as MRP8 and MRP14, respectively) are Ca2 binding proteins belonging to the S100 family. They often exist in the form of heterodimer, while homodimer exists very little because of the stabili... | |||
TMPK-01259 | S100A9 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | E. coli |
S100A8 and S100A9 (also known as MRP8 and MRP14, respectively) are Ca2 binding proteins belonging to the S100 family. They often exist in the form of heterodimer, while homodimer exists very little because of the stabili... | |||
TMPH-00744 | CsrA Protein, E. coli, Recombinant | E. coli | E. coli |
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress... | |||
TMPH-02711 | HIST1H2BM Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription... | |||
TMPH-00343 | Angiopoietin-1 Protein, Canine, Recombinant (HEK293, His) | Canine | HEK293 Cells |
Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal i... | |||
TMPH-03239 | Angiopoietin-1 Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal i... | |||
TMPH-00035 | Polyphenol oxidase 2 Protein, Agaricus bisporus, Recombinant (His) | Agaricus bisporus | Baculovirus Insect Cells |
Copper-containing oxidase that catalyzes both the o-hydroxylation of monophenols and the subsequent oxidation of the resulting o-diphenols into reactive o-quinones, which evolve spontaneously to produce intermediates, wh... | |||
TMPY-02426 | UBE2D1 Protein, Human, Recombinant (His) | Human | E. coli |
Ubiquitin-conjugating enzyme E2 D1 (UBE2D1), a member of human E2 ubiquitin-conjugating enzymes, is closely related to SFT, which is short for stimulator of iron (Fe) transport. In other words, UbcH5A is significantly up... | |||
TMPJ-00972 | CDKN1B Protein, Human, Recombinant (His) | Human | E. coli |
Cyclin-Dependent Kinase Inhibitor 1B (CDKN1B) is a Kinesin-related motor protein necessary for mitotic spindle assembly and chromosome segregation. CDKN1B is expressed in all tissues with highest levels observed in skele... | |||
TMPH-01683 | Tau Protein, Human, Recombinant (HEK293, His) | Human | HEK293 Cells |
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane com... | |||
TMPY-03983 | CIRBP Protein, Human, Recombinant (His) | Human | E. coli |
CIRBP, also known as cold-inducible RNA-binding protein, plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP responds to a wide array of cellular ... | |||
TMPY-03446 | ENO3 Protein, Human, Recombinant (His) | Human | E. coli |
ENO3 is one of the three enolase isoenzymes found in mammals. As a homodimer, ENO3 is found in skeletal muscle cells in the adult. A switch from alpha enolase to beta enolase occurs in muscle tissue during development... | |||
TMPY-04336 | Orange fluorescent protein Protein, Discosoma sp, Recombinant (His) | Discosoma sp | E. coli |
OFPSparkTM is a red (orange) fluorescent protein (excitation/emission maxima are 549 and 566 nm, respectively) derived from DsRed. Possessing high photostability and pH stability, OFPSparkTM is more than twice brighter t... | |||
TMPJ-00828 | Tau-F Protein, Human, Recombinant | Human | E. coli |
Tau proteins are proteins which contain four Tau/MAP repeats. They promote microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. They are abundant in neurons... | |||
TMPY-05028 | NOTCH2NL Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
NOTCH2NLA (Notch 2 N-Terminal Like A) is a Protein Coding gene. NOTCH2NL, human-specific paralogs of the NOTCH2 receptor, stood out for their ability to promote cortical progenitor maintenance. It belongs to the NOTCH fa... | |||
TMPJ-00200 | EpCAM/TROP1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Epithelial Cellular Adhesion Molecule (Ep-CAM), also known as EGP314, mEGP314, Protein 289A, Tumor-associated calcium signal transducer 1, CD326, belongs to the EPCAM family. Its’ monomer subunit structure interacts with... | |||
TMPJ-01386 | STUB1 Protein, Human, Recombinant | Human | E. coli |
E3 Ubiquitin-Protein Ligase CHIP is a cytoplasmic protein. CHIP is highly expressed in skeletal muscle, heart, pancreas, brain and placenta. CHIP interacts with the molecular chaperones Hsc70-Hsp70 and Hsp90 through its ... | |||
TMPY-04267 | MSH2 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
MSH2 is a key DNA mismatch repair protein, which plays an important role in genomic stability. In addition to its DNA repair function, MSH2 serves as a sensor for DNA base analogs-provoked DNA replication errors and bind... | |||
TMPH-01280 | EGLN1 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of th... | |||
TMPH-01248 | ADAR Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translatio... | |||
TMPH-01258 | DAG1 Protein, Human, Recombinant (His & Myc) | Human | Baculovirus Insect Cells |
The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epi... | |||
TMPH-01621 | BRCC3 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not have activity toward 'Lys-48'-linked polyubiquitin chains. Component of the BRCA1-A complex, a complex that specifically recognizes... | |||
TMPY-00819 | HAPLN1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Hyaluronan (HA) is a high MW glycosaminoglycan significantly involved in the formation and stability of extracellular matrix via its association with specific HA-binding proteins. HAPLN1, also known as CRTL1 (Cartilage L... | |||
TMPJ-01450 | SARS-CoV-2 Helicase Protein (His & MBP) | SARS-CoV-2 | E. coli |
The non—structural protein 13 (nsp13) of SARS—CoV 2 is a helicase that separates double—stranded RNA or DNA with a 5'—3' polarity, using the energy of nucleotide hydrolysis. A basic biochemical characterization of nsp13 ... | |||
TMPY-01927 | ANP32A Protein, Human, Recombinant (His & GST) | Human | E. coli |
acidic leucine-rich nuclear phosphoprotein 32 family member A, also known as acidic nuclear phosphoprotein pp32, Leucine-rich acidic nuclear protein, Mapmodulin, Potent heat-stable protein phosphatase 2A inhibitor I1P... | |||
TMPY-01332 | HIST1H3A Protein, Human, Mouse, Recombinant | Human,Mouse | E. coli |
Histone H3.1, also known as HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, is a member of the histone H3 family which is a core component of nucleosome. It is expresse... | |||
TMPH-01664 | OMA1 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Activated in response to various mitochondrial stress, leading to the proteolytic cleavage of target proteins, such as OPA... | |||
TMPY-02150 | GADD45A Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
GADD45A is a member of the GADD45 Family, and has been found to associate with several cytoplasmic and nuclear factors and has been implicated in several cellular functions, including MAPK signaling, cell cycle regulatio... | |||
TMPH-01270 | TRAIP Protein, Human, Recombinant (His) | Human | E. coli |
E3 ubiquitin ligase required to protect genome stability in response to replication stress. Acts as a key regulator of interstrand cross-link repair, which takes place when both strands of duplex DNA are covalently tethe... | |||
TMPY-04550 | JNK2 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Mitogen-activated protein kinase 9 (MAPK9), also well known as c-Jun N-terminal kinase (JNK2), is a member of the MAP kinase subfamily belonging to the protein kinase superfamily. MAPK9 responds to activation by environm... | |||
TMPH-02133 | DDX39B Protein, Human, Recombinant (GST) | Human | E. coli |
Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mR... | |||
TMPH-01689 | PLD6 Protein, Human, Recombinant (His) | Human | E. coli |
Presents phospholipase and nuclease activities, depending on the different physiological conditions. Interaction with Mitoguardin (MIGA1 or MIGA2) affects the dimer conformation, facilitating the lipase activity over the... | |||
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カタログ番号 | 製品名 | ||
---|---|---|---|
L7820 | High Solubility Micro Fragment Library | 1081 compounds | |
The compound library of highly soluble micro-fragments consists of 1081 low-molecular-weight fragments. | |||
L9610 | Cyclic Peptide Library | 55 compounds | |
55 species of cyclic peptide molecules for high-throughput and high-content screening; | |||
L3510 | Methylation Compound Library | 128 compounds | |
128 methylation-related compounds that can be used for high-throughput and high-content screening. | |||
L9900 | Inactive Ingredient Library | 182 compounds | |
L5100 | Fluorochemical Library | 574 compounds | |
A unique collection of 574 fluorochemicals that can be used for high through-put screening (HTS) and high content screening (HCS); | |||
L1310 | Cytoskeletal Signaling Pathway Compound Library | 759 compounds | |
A unique collection of 759 cytoskeleton-related compounds, can be used for HTS and HCS; |