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Search Results for " stability "

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243

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16

天然化合物

51

リコンビナントタンパク質

6

ライブラリー

カタログ番号 製品名 別名 ターゲット
T7879 TASP0415914 Akt , PI3K
TASP0415914 is an orally potent inhibitor of phosphoinositide 3-kinase γ (PI3Kγ). T
T6928 Pantoprazole SKF96022,BY1023 Apoptosis , Proton pump , Autophagy
Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.
T0161 Pantoprazole Sodium Hydrate SKF96022 sodium hydrate,BY1023 (sodium hydrate),SKF96022 (sodium hydrate) Apoptosis , Potassium Channel , Proton pump , Autophagy
Pantoprazole Sodium Hydrate (BY1023 (sodium hydrate)) is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.
T6929 Pantoprazole sodium Pantecta,SKF96022 sodium,SKF96022 (sodium),BY1023 (sodium),BY-1023 sodium,Pantoloc Apoptosis , Others , Proton pump , HIF , Autophagy
Pantoprazole sodium (Pantecta) is the sodium salt form of a substituted benzimidazole with proton pump inhibitor activity. Pantoprazole sodium is a lipophilic, weak base that crosses the parietal cell membrane and enters...
T20075 Sodium dodecyl sulfate Laurylsulfuric acid sodium salt,NSC 402488,Anticerumen,NSC-402488,NSC402488,Natrium laurylsulfuricum,Sodium dodecylsulfate,Sodium lauryl sulfate Others
Sodium dodecyl sulfate(Sodium lauryl sulfate) is a pharmaceutical excipient that is biologically inactive and improves the stability, solubility and processability of pharmaceutical preparations.
T19853 Dimethoxycurcumin Veratrylcurcuminoid Others
Dimethoxycurcumin (Veratrylcurcuminoid) is an analog of curcumin with more metabolical stability. Dimethoxycurcumin induces epigenetic changes in leukemia cells and the expression of promoter methylated genes.
T28973 TIBI Others
TIBI is an ATP-competitive Rio1 inhibitor that acts in a similar manner to fungamycin and enhances the thermal stability of the enzyme.
T10002 (E)-Crotylbarbital Kalypnon Others
(E)-Crotylbarbital (Kalypnon), an isomer of Crotylbarbital, is a barbiturate derivative that has sedative, hypnotic, and anticonvulsant effects. (E)-Crotylbarbital can be used in studies to promote mental stability and s...
T19609 HP-β-CD Hydroxypropyl-β-cyclodextrin,Hydroxypropyl betadex Others
HP-β-CD (HP-β-CD) is a widely used drug delivery vehicle to improve stability and bioavailability.
T9058 Bisphenoxyethanolfluorene Others
Bisphenoxyethanolfluorene a high stability of the new type of organic chemical raw materials, mainly used for synthesis of heat resistance, excellent transparency and high refractive index of polymer monomer
T6705 TIC10 Isomer ONC201 isomer,TIC10 Analogue Others
TIC10 Isomer (ONC201 isomer) is an isomer of TIC10, which inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improv...
T29059 UMK57 UMK 57,UMK-57 Kinesin
UMK57 is a CENP-Ei and MCAK enhancer, selectively promoting k-MT attachment error correction to inhibit chromosome missegregation of small molecule compounds, and can improve chromosome separation conservation by disrupt...
T15409 GNF179 Parasite
GNF179 is an optimized 8,8-dimethyl IP analog. It exhibited the potency(4.8 nM against the multidrug resistant strain W2) in vitro metabolic stability and in vivo oral bioavailability.
T73040 CYP1B1-IN-4 P450
CYP1B1-IN-4, a 2,4-diarylthiazole compound, exhibits selective inhibition of CYP1B1 (IC50=0.2 nM), demonstrating minimal cytotoxicity and high stability in human and rat liver microsomes [1].
T11717 JHU395 Apoptosis
T9698 UC2288 Mdm2 , p53
UC2288 is a relatively selective p21 attenuator which is synthesized based Sorafenib. UC2288 attenuates p21 protein levels with minimal effect on p21 protein stability.
T21673 N-Isopropylnoratropine Others
N-Isopropylnoratropine is a noratropine derivative and an intermediate in the production of ipratropium, an atropine-like bronchodilator drug via an anticholinergic pathway. N-Isopropylnoratropine is used to examine the ...
T0901 Chlorobutanol Chlortran,Chloretone,YM-57158,Chlorbutol,Chloreton Antibacterial , Antibiotic , Antifungal
Chlorobutanol (Chlortran) is a chemical preservative, sedative hypnotic and weak local anaesthetic. It has Antibacterial and Antifungal properties. Chlorobutanol is typically used at a concentration of 0.5% where it lend...
T3622 CP-640186 hydrochloride CP 640186 HCl Acetyl-CoA Carboxylase
CP-640186 hydrochloride (CP 640186 HCl) is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor, including rat liver ACC1 (IC50: 53 nM) and rat skeletal muscle ACC2 (IC50: 61 nM); with higher metabolic stabilit...
T7001 TIC10 ONC-201 Apoptosis , TNF
TIC10 (ONC-201) inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improved pharmacokinetics. Phase 1/2.
T7423 Diquafosol tetrasodium INS365 P2Y Receptor
Diquafosol Tetrasodium is a P2Y2 receptor agonist that stimulates the secretion of mucins from ocular tissues Diquafosol tetrasodium (INS365) improves tear film stability and visual function, as a topical treatment of dr...
T8670 Fmoc-L-2-cyanophenylalanine Others
fmoc-L-2-cyanophenylalanine is a derivative of the amino acid phenylalanine. Due to its excellent reactivity and stability, it is widely used in peptide synthesis, as well as in the synthesis of a variety of other biolog...
T5593 L-Alanyl-L-glutamine Ala-Gln Others , Endogenous Metabolite
L-Alanyl-L-glutamine (Ala-Gln), a dipeptide composed of alanine and Gln, is an alternative supplement to L-glutamine in the production of biopharmaceuticals with better solubility and stability than glutamine (Gln).
T60084 FINO2 Ferroptosis
FINO2 is a potent ferroptosis-inducing compound that inhibits GPX4 activity. It functions as a stable oxidant, effectively oxidizing ferrous iron and demonstrating stability across varying pH levels. Furthermore, FINO2 i...
T38651 Lauryl maltose neopentyl glycol LMNG
Lauryl maltose neopentyl glycol (LMNG) is a detergent that solubilizes and stabilizes membrane proteins. lauryl maltose neopentyl glycol extracts intact membrane proteins from membranes, thereby improving the stability o...
T20870 IR-820 IR 820,IR820,New Indocyanine Green
IR-820 (New Indocyanine Green) is a near-infrared dye with better stability, good color rendering, and excellent fluorescence penetration. IR-820 is an infrared blood pool contrast agent used to detect and quantify disea...
T9394 CHIKV-IN-2 Dehydrogenase
CHIKV-IN-2, a chemical compound, exhibits potent inhibitory activity against the enzyme Dihydroorotate Dehydrogenase (DHODH), crucial for pyrimidine synthesis affecting various viruses' replication. It serves as an effec...
T22530 6-Chloromelatonin Melatonin Receptor , Dopamine Receptor
6-Chloromelatonin is a potent melatonin receptor agonist, a 5-methoxyindole compound that competes for the same presynaptic melatonin receptor sites in the rabbit retina and inhibits the calcium-dependent release of [3H]...
T0932 Cefixime FK-027,Cefspan,Cefiximum,Cephoral,FR-17027,CL-284635 Antibacterial , Antibiotic
Cefixime (FR-17027) is a broad-spectrum, third-generation cephalosporin antibiotic derived semisynthetically from the marine fungus Cephalosporium acremonium with antibacterial activity. As does penicillin, the beta-lact...
T8947 Dasiglucagon acetate dasiglucagon acetate(1544300-84-6 free base) Others
Dasiglucagon acetate is a novel glucagon analog for diabetic hypoglycemia therapy. Dasiglucagon acetate has demonstrated established solubility and stability in an aqueous formulation. Pharmacokinetics studies have shown...
T1224 Cefuroxime sodium Anaptivan,Cefuroxime sodium salt,Biociclin Antibacterial , Antibiotic
Cefuroxime Sodium is the sodium salt form of cefuroxime and a semi-synthetic, broad-spectrum, beta-lactamase resistant, second-generation cephalosporin antibiotic with bactericidal activity. Cefuroxime sodium (Cefuroxime...
T67831 HIF-2α agonist 2 HIF/HIF Prolyl-Hydroxylase , HIF
HIF-2α agonist 2 is an HIF-2α agonist with an EC50 value of 1.68 μM for HIF-2α. HIF-2α agonist 2 can promote the stability of the ARNT A/B ring in the 3z structure of HIF-2a-ARNT complex without cytotoxicity to 786-o-Reh...
T74485 STC314 Others
STC314 is an anti-infective agent that reverses organ damage caused by excessive immune response by neutralizing extracellular histones and neutrophil trapping networks, and can be used in the study of sepsis and acute r...
T60877 Mtb ATP synthase-IN-1
Mtb ATP synthase-IN-1 (compound 6ab) can be used in anti-mycobacterium research. Mtb ATP synthase-IN-1 shoys low cytotoxicity (Vero IC 50 > 64 μg/mL) and acceptable oral bioavailability that has good metabolic stability....
T6284 Onalespib AT13387,Onalespib (AT13387) HSP
Onalespib (AT13387) is a synthetic, orally bioavailable, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. Onalespib selectively binds to Hsp90, thereby inhibiting its chap...
T61268 Vutiglabridin HSG4112 Phosphatase
Vutiglabridin (HSG4112) is a novel and safe modulator of PON2, a racemic compound. vutiglabridin is an optimized structural analogue of Glabridin and is superior to Glabridin in terms of weight loss and chemical stabilit...
T29244 (+)-Carbovir L-Carbovir
(+)-Carbovir is a nucleoside analog with increased chemical stability and increased metabolic stability.
T31523 Diptoindonesin G
Diptoindonesin G is an ERß stabilizer that regulates the stability of ERα and ERß by targeting CHIP E3 ubiquitin ligase. Diptoindonesin G could significantly increase the protein stability of ERß, and reduce the protein ...
T10845 CMK Others
CMK, an RSK2 kinase inhibitor, shows similar potency but less chemical stability compared with FMK.
T13548 AN7973 Others
AN7973 blocks intracellular parasite development and inhibits Cryptosporidium growth. It is orally active, possesses favorable safety, stability, and PK parameters.
T70091 IACS-4759
IACS-4759 is a novel potent and selective MTH1 inhibitor with excellent cell permeability and good metabolic stability in microsomes.
T38707 MPC-0767
MPC-0767, a potent, selective, and orally active hsp90 inhibitor, is the L-alanine ester prodrug of MPC-3100, exhibiting enhanced chemical stability.
T32242 IWP-051 IWP051
IWP-051 is a potent, orally active sGC stimulator (EC50 = 290nM). IWP-051 showed >99% plasma protein binding, high metabolic stability, high permeability, and no efflux in a Caco-2 model of intestinal absorption. IWP-...
T39680 Diflomotecan BN 80915
Diflomotecan (BN 80915) is a potent, orally active topoisomerase I inhibitor that displays enhanced plasma stability and superior preclinical anti-tumor activity relative to other established compounds.
T29077 Urolinin nWWK-Tyr(3-NO2)-Abu
Urolinin is a linear peptidic Urotensin-II Receptor Agonist with low nanomolar potency as well as improved metabolic stability. Urolinin is a hexameric UIIR agonist with an EC50 of 4.75 nM and a metabolic stability of 13...
T19773 Diethyl bipy55'DC
Diethyl bipy55'DC inhibits CP4H activity in cultured cells. The stability of collagen relies on post-translational modifications, the most prevalent being the hydroxylation of collagen strands by collagen prolyl 4-hydrox...
T31174 DABA diaminobenzoic acid
DABA (diaminobenzoic acid) can react with all aldehydes in the form of RCH(2)CHO, has the high serum stability of oligomers, and will develop new nanomaterials in biotechnology and biomedical applications.
T23596 A-933548 A933548,A 933548
A-933548 is a potent Calpain inhibitor. A-933548 features enhanced selectivity versus related cysteine protease cathepsins, favorable microsomal stability, and efficacy in cellular assays.
T11445 GNF179 (Metabolite) GNF179 Metabolite Others
GNF179 Metabolite, the derivative of GNF179—an optimized 8,8-dimethyl IP analog—demonstrates significant potency (4.8 nM against the multidrug-resistant W2 strain) alongside in vitro metabolic stability and in vivo oral ...
T83187 AChE-IN-41
AChE-IN-41 (Compound 2), a Galantamine-Memantine hybrid, possesses cholinesterase inhibitory capabilities. This compound demonstrates enhanced plasma stability and similar microsomal stability in vitro but has a reduced ...

Compounds

TASP0415914
T7879
Synonym:
Target: Akt, PI3K
Pantoprazole
T6928
Synonym: SKF96022,BY1023
Target: Apoptosis, Proton pump, Autophagy
Pantoprazole Sodium Hydrate
T0161
Synonym: SKF96022 sodium hydrate,BY1023 (sodium hydrate),SKF96022 (sodium hydrate)
Target: Apoptosis, Potassium Channel, Proton pump, Autophagy
Pantoprazole sodium
T6929
Synonym: Pantecta,SKF96022 sodium,SKF96022 (sodium),BY1023 (sodium),BY-1023 sodium,Pantoloc
Target: Apoptosis, Others, Proton pump, HIF, Autophagy
Sodium dodecyl sulfate
T20075
Synonym: Laurylsulfuric acid sodium salt,NSC 402488,Anticerumen,NSC-402488,NSC402488,Natrium laurylsulfuricum,Sodium dodecylsulfate,Sodium lauryl sulfate
Target: Others
Dimethoxycurcumin
T19853
Synonym: Veratrylcurcuminoid
Target: Others
TIBI
T28973
Synonym:
Target: Others
(E)-Crotylbarbital
T10002
Synonym: Kalypnon
Target: Others
HP-β-CD
T19609
Synonym: Hydroxypropyl-β-cyclodextrin,Hydroxypropyl betadex
Target: Others
Bisphenoxyethanolfluorene
T9058
Synonym:
Target: Others
TIC10 Isomer
T6705
Synonym: ONC201 isomer,TIC10 Analogue
Target: Others
UMK57
T29059
Synonym: UMK 57,UMK-57
Target: Kinesin
GNF179
T15409
Synonym:
Target: Parasite
CYP1B1-IN-4
T73040
Synonym:
Target: P450
JHU395
T11717
Synonym:
Target: Apoptosis
UC2288
T9698
Synonym:
Target: Mdm2, p53
N-Isopropylnoratropine
T21673
Synonym:
Target: Others
Chlorobutanol
T0901
Synonym: Chlortran,Chloretone,YM-57158,Chlorbutol,Chloreton
Target: Antibacterial, Antibiotic, Antifungal
CP-640186 hydrochloride
T3622
Synonym: CP 640186 HCl
Target: Acetyl-CoA Carboxylase
TIC10
T7001
Synonym: ONC-201
Target: Apoptosis, TNF
Diquafosol tetrasodium
T7423
Synonym: INS365
Target: P2Y Receptor
fmoc-L-2-cyanophenylalanine
T8670
Synonym:
Target: Others
L-Alanyl-L-glutamine
T5593
Synonym: Ala-Gln
Target: Others, Endogenous Metabolite
FINO2
T60084
Synonym:
Target: Ferroptosis
Lauryl maltose neopentyl glycol
T38651
Synonym: LMNG
Target:
IR-820
T20870
Synonym: IR 820,IR820,New Indocyanine Green
Target:
CHIKV-IN-2
T9394
Synonym:
Target: Dehydrogenase
6-Chloromelatonin
T22530
Synonym:
Target: Melatonin Receptor, Dopamine Receptor
Cefixime
T0932
Synonym: FK-027,Cefspan,Cefiximum,Cephoral,FR-17027,CL-284635
Target: Antibacterial, Antibiotic
dasiglucagon acetate
T8947
Synonym: dasiglucagon acetate(1544300-84-6 free base)
Target: Others
Cefuroxime sodium
T1224
Synonym: Anaptivan,Cefuroxime sodium salt,Biociclin
Target: Antibacterial, Antibiotic
HIF-2α agonist 2
T67831
Synonym:
Target: HIF/HIF Prolyl-Hydroxylase, HIF
STC314
T74485
Synonym:
Target: Others
Mtb ATP synthase-IN-1
T60877
Synonym:
Target:
Onalespib
T6284
Synonym: AT13387,Onalespib (AT13387)
Target: HSP
Vutiglabridin
T61268
Synonym: HSG4112
Target: Phosphatase
(+)-Carbovir
T29244
Synonym: L-Carbovir
Target:
Diptoindonesin G
T31523
Synonym:
Target:
CMK
T10845
Synonym:
Target: Others
AN7973
T13548
Synonym:
Target: Others
IACS-4759
T70091
Synonym:
Target:
MPC-0767
T38707
Synonym:
Target:
IWP-051
T32242
Synonym: IWP051
Target:
Diflomotecan
T39680
Synonym: BN 80915
Target:
Urolinin
T29077
Synonym: nWWK-Tyr(3-NO2)-Abu
Target:
Diethyl bipy55'DC
T19773
Synonym:
Target:
DABA
T31174
Synonym: diaminobenzoic acid
Target:
A-933548
T23596
Synonym: A933548,A 933548
Target:
GNF179 (Metabolite)
T11445
Synonym: GNF179 Metabolite
Target: Others
AChE-IN-41
T83187
Synonym:
Target:
1 2 3 4 5
カタログ番号 製品名 別名 ターゲット
T5080 Spermidine trihydrochloride Spermidine hydrochloride,4-Azaoctamethylenediamine trihydrochloride NMDAR , Autophagy
Spermidine trihydrochloride (4-Azaoctamethylenediamine trihydrochloride), a natural polyamine, is a novel autophagy inducer and negatively modulates N-methyl-d-aspartate (NMDA).
T4893 Spermidine N-(3-Aminopropyl)-1,4-diaminobutane,N-(4-Aminobutyl)-1,3-diaminopropane Endogenous Metabolite
Spermidine (N-(3-Aminopropyl)-1,4-diaminobutane) inhibits NOS1 (nNOS). Spermidine binds and precipitates DNA and may be used for purification of DNA binding proteins. Spermidine activates PNK (polynucleotide kinase T4). ...
T4925 Thiamine monophosphate chloride (dihydrate) Thiamine monophosphate chloride dihydrat,Aneurine monophosphate chloride Others , Endogenous Metabolite
Thiamine monophosphate chloride dihydrate (Aneurine monophosphate chloride) is a compound used in the screening of ligands that promote protein stability
T4S2014 5,15-Diacetyl-3-benzoyllathyrol Euphorbia factor L3 Others
1. 5,15-Diacetyl-3-benzoyllathyrol (Euphorbia factor L3) is a melanine production inhibitor, excellent in inhibiting pigment stagnation and improving the discoloration of the skin or freckles, has excellent stability.
T4A2456 Gamabufotalin Gamabufagin COX
1. Gamabufotalin (Gamabufagin) , a major bufadienolide of Chansu, has been used for treatment of COX-2-mediated diseases and cancer therapy due to its desirable metabolic stability and less adverse effect.
T2S1840 Rebaudioside D Others
Rebaudioside D is a potential sweetener. Rebaudioside D shows similar stability when exposed to simulate stomach and small intestine fluids, with susceptibility to hydrolytic degradation by enteric bacteria collected fro...
T8160 EGCG Octaacetate Others , Antibacterial
EGCG Octaacetate, a prodrug of EGCG, is utilized to enhance the stability and bioavailability of EGCG in vivo. It has high efficacy, bioavailability, anti-oxidation, and anti-angiogenesis capacities.
TN1608 (-)-Epigallocatechin-3-(3''-O-methyl) gallate (-)-EGCG-3''-O-ME Antioxidant , Antibacterial
(-)-Epigallocatechin-3-(3''-O-methyl) gallate ((-)-EGCG-3''-O-ME) is a natural product isolated from tea leaves with strong antioxidant, cytotoxic and antibacterial activity, which enhances the adhesive stability of etch...
TN1275 P-Hydroxyphenethyl anisate 4-Hydroxyphenethylanisate Others
p-Hydroxyphenethyl anisate (4-Hydroxyphenethylanisate), a natural product from Notopterygium forbe-siiBoiss, is a novel polymeric sustained-release material that, after block copolymerization with AAPBA, produces nanopar...
T14862 Caprylic/Capric Triglyceride Others
Caprylic/Capric Triglyceride, a compound consisting of triglycerides and esters derived from fractionated vegetable oil, and fatty acids from coconut and palm kernel oils, serves as a food additive and is utilized in cos...
T5669 Citric acid monohydrate Others
Citric Acid Monohydrate is a tricarboxylic acid found in citrus fruits. Citric acid is used as an excipient in pharmaceutical preparations due to its antioxidant properties. It maintains stability of active ingredients a...
T8733 Antrodin A camphorataanhydride A Others
Antrodin A (camphorataanhydride A) (AdA) is one of the main active ingredients in the solid-state fermented A. camphorata mycelium. It protects the liver from alcohol damage by improving the antioxidant and anti-inflamma...
T37520 DL-Glutamic acid
DL-Glutamic acid, the conjugate acid of Glutamic acid, serves as a crucial metabolite. In comparison to the α and β polymorphs of L-Glutamic acid's second phase, DL-Glutamic acid exhibits enhanced stability[1].
T83725 Nigerose Sakebiose
Nigerose, a disaccharide identified in Acremonium, effectively maintains stability in HL-60 cells post-cryopreservation by preventing elevations in malondialdehyde (MDA) and reactive oxygen species (ROS) levels, and inhi...
T80950 Tricetin 7-O-glucoside
Chemical Compound 77298-67-0 exhibits high thermal stability and outstanding resistance to both corrosion and oxidation, suitable for extreme environmental conditions. Its melting point lies above 3500°C. The compound de...
T37770 Taurohyodeoxycholic acid
Taurohyodeoxycholic acid (THDCA) is a taurine-conjugated form of the secondary bile acid hyodeoxycholic acid .1THDCA decreases the size and weight of human gallstonesin vitro. It increases bile flow, biliary cholesterol ...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-03425 Tau Protein, Human, Recombinant (His) Human E. coli
MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are...
TMPH-01653 MLANA Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage ...
TMPH-01652 MLANA Protein, Human, Recombinant (B2M & His) Human E. coli
Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage ...
TMPH-02840 PLOD2 Protein, Mouse, Recombinant (E. coli, His & Myc) Mouse E. coli
Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-link...
TMPH-01879 PARP11 Protein, Human, Recombinant (His) Human E. coli
Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins. Plays a role in nuclear envelope stability and nuclear remodeling during spermiogenesis. PARP11 Protein, Human, Recombinant (His) is exp...
TMPY-04073 MRPL44 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
MRPL44 (Mitochondrial Ribosomal Protein L44) is a Protein Coding gene. MRPL44 encodes a protein in the large subunit of the mitochondrial ribosome and is suggested to locate near the tunnel exit of the yeast mitochondria...
TMPH-02839 PLOD2 Protein, Mouse, Recombinant (His & Myc) Mouse Baculovirus Insect Cells
Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-link...
TMPH-03713 ELAVL4 Protein, Xenopus tropicalis, Recombinant (His) Xenopus tropicalis E. coli
RNA-binding protein that is involved in the post-transcriptional regulation of mRNAs. Plays a role in the regulation of mRNA stability, alternative splicing and translation. Binds to AU-rich element (ARE) sequences in th...
TMPH-03748 KAT14 Protein, Human, Recombinant (His) Human E. coli
Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. May function as a scaffold for the ATAC complex to promote ATAC complex stability. Has also weak histone acetyltrans...
TMPH-01979 SFTPB Protein, Human, Recombinant Human P. pastoris (Yeast)
Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearl...
TMPH-01257 Dystonin Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and musc...
TMPH-01256 Dystonin Protein, Human, Recombinant (His & SUMO) Human E. coli
Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and musc...
TMPH-03334 Mitofilin Protein, Rat, Recombinant (His) Rat E. coli
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to ...
TMPH-03375 Stathmin-2 Protein, Rat, Recombinant (His) Rat E. coli
Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in cortical neurons. In the developing brain, negatively regulates the rate of exit from ...
TMPH-02317 YTHDF1 Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and regulates their stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stabi...
TMPH-03193 Alba Protein, Pyrococcus furiosus, Recombinant (His & SUMO) Pyrococcus furiosus E. coli
Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DN...
TMPH-00479 Angiopoietin-1 Protein, Canine, Recombinant (His) Canine Baculovirus Insect Cells
Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal i...
TMPH-01322 FANCC Protein, Human, Recombinant (His & SUMO) Human E. coli
DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG...
TMPK-01324 S100A9 Protein, Canine, Recombinant (His) Canine E. coli
S100A8 and S100A9 (also known as MRP8 and MRP14, respectively) are Ca2 binding proteins belonging to the S100 family. They often exist in the form of heterodimer, while homodimer exists very little because of the stabili...
TMPK-01259 S100A9 Protein, Cynomolgus, Recombinant (His) Cynomolgus E. coli
S100A8 and S100A9 (also known as MRP8 and MRP14, respectively) are Ca2 binding proteins belonging to the S100 family. They often exist in the form of heterodimer, while homodimer exists very little because of the stabili...
TMPH-00744 CsrA Protein, E. coli, Recombinant E. coli E. coli
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress...
TMPH-02711 HIST1H2BM Protein, Mouse, Recombinant (His) Mouse E. coli
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription...
TMPH-00343 Angiopoietin-1 Protein, Canine, Recombinant (HEK293, His) Canine HEK293 Cells
Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal i...
TMPH-03239 Angiopoietin-1 Protein, Rat, Recombinant (His) Rat HEK293 Cells
Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal i...
TMPH-00035 Polyphenol oxidase 2 Protein, Agaricus bisporus, Recombinant (His) Agaricus bisporus Baculovirus Insect Cells
Copper-containing oxidase that catalyzes both the o-hydroxylation of monophenols and the subsequent oxidation of the resulting o-diphenols into reactive o-quinones, which evolve spontaneously to produce intermediates, wh...
TMPY-02426 UBE2D1 Protein, Human, Recombinant (His) Human E. coli
Ubiquitin-conjugating enzyme E2 D1 (UBE2D1), a member of human E2 ubiquitin-conjugating enzymes, is closely related to SFT, which is short for stimulator of iron (Fe) transport. In other words, UbcH5A is significantly up...
TMPJ-00972 CDKN1B Protein, Human, Recombinant (His) Human E. coli
Cyclin-Dependent Kinase Inhibitor 1B (CDKN1B) is a Kinesin-related motor protein necessary for mitotic spindle assembly and chromosome segregation. CDKN1B is expressed in all tissues with highest levels observed in skele...
TMPH-01683 Tau Protein, Human, Recombinant (HEK293, His) Human HEK293 Cells
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane com...
TMPY-03983 CIRBP Protein, Human, Recombinant (His) Human E. coli
CIRBP, also known as cold-inducible RNA-binding protein, plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP responds to a wide array of cellular ...
TMPY-03446 ENO3 Protein, Human, Recombinant (His) Human E. coli
ENO3 is one of the three enolase isoenzymes found in mammals. As a homodimer, ENO3 is found in skeletal muscle cells in the adult. A switch from alpha enolase to beta enolase occurs in muscle tissue during development...
TMPY-04336 Orange fluorescent protein Protein, Discosoma sp, Recombinant (His) Discosoma sp E. coli
OFPSparkTM is a red (orange) fluorescent protein (excitation/emission maxima are 549 and 566 nm, respectively) derived from DsRed. Possessing high photostability and pH stability, OFPSparkTM is more than twice brighter t...
TMPJ-00828 Tau-F Protein, Human, Recombinant Human E. coli
Tau proteins are proteins which contain four Tau/MAP repeats. They promote microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. They are abundant in neurons...
TMPY-05028 NOTCH2NL Protein, Human, Recombinant (mFc) Human HEK293 Cells
NOTCH2NLA (Notch 2 N-Terminal Like A) is a Protein Coding gene. NOTCH2NL, human-specific paralogs of the NOTCH2 receptor, stood out for their ability to promote cortical progenitor maintenance. It belongs to the NOTCH fa...
TMPJ-00200 EpCAM/TROP1 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Epithelial Cellular Adhesion Molecule (Ep-CAM), also known as EGP314, mEGP314, Protein 289A, Tumor-associated calcium signal transducer 1, CD326, belongs to the EPCAM family. Its’ monomer subunit structure interacts with...
TMPJ-01386 STUB1 Protein, Human, Recombinant Human E. coli
E3 Ubiquitin-Protein Ligase CHIP is a cytoplasmic protein. CHIP is highly expressed in skeletal muscle, heart, pancreas, brain and placenta. CHIP interacts with the molecular chaperones Hsc70-Hsp70 and Hsp90 through its ...
TMPY-04267 MSH2 Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
MSH2 is a key DNA mismatch repair protein, which plays an important role in genomic stability. In addition to its DNA repair function, MSH2 serves as a sensor for DNA base analogs-provoked DNA replication errors and bind...
TMPH-01280 EGLN1 Protein, Human, Recombinant (His & Myc) Human E. coli
Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of th...
TMPH-01248 ADAR Protein, Human, Recombinant (His & SUMO) Human E. coli
Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translatio...
TMPH-01258 DAG1 Protein, Human, Recombinant (His & Myc) Human Baculovirus Insect Cells
The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epi...
TMPH-01621 BRCC3 Protein, Human, Recombinant (His & SUMO) Human E. coli
Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not have activity toward 'Lys-48'-linked polyubiquitin chains. Component of the BRCA1-A complex, a complex that specifically recognizes...
TMPY-00819 HAPLN1 Protein, Human, Recombinant (His) Human HEK293 Cells
Hyaluronan (HA) is a high MW glycosaminoglycan significantly involved in the formation and stability of extracellular matrix via its association with specific HA-binding proteins. HAPLN1, also known as CRTL1 (Cartilage L...
TMPJ-01450 SARS-CoV-2 Helicase Protein (His & MBP) SARS-CoV-2 E. coli
The non—structural protein 13 (nsp13) of SARS—CoV 2 is a helicase that separates double—stranded RNA or DNA with a 5'—3' polarity, using the energy of nucleotide hydrolysis. A basic biochemical characterization of nsp13 ...
TMPY-01927 ANP32A Protein, Human, Recombinant (His & GST) Human E. coli
acidic leucine-rich nuclear phosphoprotein 32 family member A, also known as acidic nuclear phosphoprotein pp32, Leucine-rich acidic nuclear protein, Mapmodulin, Potent heat-stable protein phosphatase 2A inhibitor I1P...
TMPY-01332 HIST1H3A Protein, Human, Mouse, Recombinant Human,Mouse E. coli
Histone H3.1, also known as HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, is a member of the histone H3 family which is a core component of nucleosome. It is expresse...
TMPH-01664 OMA1 Protein, Human, Recombinant (His & SUMO) Human E. coli
Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Activated in response to various mitochondrial stress, leading to the proteolytic cleavage of target proteins, such as OPA...
TMPY-02150 GADD45A Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
GADD45A is a member of the GADD45 Family, and has been found to associate with several cytoplasmic and nuclear factors and has been implicated in several cellular functions, including MAPK signaling, cell cycle regulatio...
TMPH-01270 TRAIP Protein, Human, Recombinant (His) Human E. coli
E3 ubiquitin ligase required to protect genome stability in response to replication stress. Acts as a key regulator of interstrand cross-link repair, which takes place when both strands of duplex DNA are covalently tethe...
TMPY-04550 JNK2 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
Mitogen-activated protein kinase 9 (MAPK9), also well known as c-Jun N-terminal kinase (JNK2), is a member of the MAP kinase subfamily belonging to the protein kinase superfamily. MAPK9 responds to activation by environm...
TMPH-02133 DDX39B Protein, Human, Recombinant (GST) Human E. coli
Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mR...
TMPH-01689 PLD6 Protein, Human, Recombinant (His) Human E. coli
Presents phospholipase and nuclease activities, depending on the different physiological conditions. Interaction with Mitoguardin (MIGA1 or MIGA2) affects the dimer conformation, facilitating the lipase activity over the...
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Tau Protein, Human, Recombinant (His)
TMPY-03425
Species: Human
Expression System: E. coli
MLANA Protein, Human, Recombinant (His)
TMPH-01653
Species: Human
Expression System: P. pastoris (Yeast)
MLANA Protein, Human, Recombinant (B2M & His)
TMPH-01652
Species: Human
Expression System: E. coli
PLOD2 Protein, Mouse, Recombinant (E. coli, His & Myc)
TMPH-02840
Species: Mouse
Expression System: E. coli
PARP11 Protein, Human, Recombinant (His)
TMPH-01879
Species: Human
Expression System: E. coli
MRPL44 Protein, Human, Recombinant (His)
TMPY-04073
Species: Human
Expression System: Baculovirus Insect Cells
PLOD2 Protein, Mouse, Recombinant (His & Myc)
TMPH-02839
Species: Mouse
Expression System: Baculovirus Insect Cells
ELAVL4 Protein, Xenopus tropicalis, Recombinant (His)
TMPH-03713
Species: Xenopus tropicalis
Expression System: E. coli
KAT14 Protein, Human, Recombinant (His)
TMPH-03748
Species: Human
Expression System: E. coli
SFTPB Protein, Human, Recombinant
TMPH-01979
Species: Human
Expression System: P. pastoris (Yeast)
Dystonin Protein, Human, Recombinant (His)
TMPH-01257
Species: Human
Expression System: P. pastoris (Yeast)
Dystonin Protein, Human, Recombinant (His & SUMO)
TMPH-01256
Species: Human
Expression System: E. coli
Mitofilin Protein, Rat, Recombinant (His)
TMPH-03334
Species: Rat
Expression System: E. coli
Stathmin-2 Protein, Rat, Recombinant (His)
TMPH-03375
Species: Rat
Expression System: E. coli
YTHDF1 Protein, Human, Recombinant (His)
TMPH-02317
Species: Human
Expression System: P. pastoris (Yeast)
Alba Protein, Pyrococcus furiosus, Recombinant (His & SUMO)
TMPH-03193
Species: Pyrococcus furiosus
Expression System: E. coli
Angiopoietin-1 Protein, Canine, Recombinant (His)
TMPH-00479
Species: Canine
Expression System: Baculovirus Insect Cells
FANCC Protein, Human, Recombinant (His & SUMO)
TMPH-01322
Species: Human
Expression System: E. coli
S100A9 Protein, Canine, Recombinant (His)
TMPK-01324
Species: Canine
Expression System: E. coli
S100A9 Protein, Cynomolgus, Recombinant (His)
TMPK-01259
Species: Cynomolgus
Expression System: E. coli
CsrA Protein, E. coli, Recombinant
TMPH-00744
Species: E. coli
Expression System: E. coli
HIST1H2BM Protein, Mouse, Recombinant (His)
TMPH-02711
Species: Mouse
Expression System: E. coli
Angiopoietin-1 Protein, Canine, Recombinant (HEK293, His)
TMPH-00343
Species: Canine
Expression System: HEK293 Cells
Angiopoietin-1 Protein, Rat, Recombinant (His)
TMPH-03239
Species: Rat
Expression System: HEK293 Cells
Polyphenol oxidase 2 Protein, Agaricus bisporus, Recombinant (His)
TMPH-00035
Species: Agaricus bisporus
Expression System: Baculovirus Insect Cells
UBE2D1 Protein, Human, Recombinant (His)
TMPY-02426
Species: Human
Expression System: E. coli
CDKN1B Protein, Human, Recombinant (His)
TMPJ-00972
Species: Human
Expression System: E. coli
Tau Protein, Human, Recombinant (HEK293, His)
TMPH-01683
Species: Human
Expression System: HEK293 Cells
CIRBP Protein, Human, Recombinant (His)
TMPY-03983
Species: Human
Expression System: E. coli
ENO3 Protein, Human, Recombinant (His)
TMPY-03446
Species: Human
Expression System: E. coli
Orange fluorescent protein Protein, Discosoma sp, Recombinant (His)
TMPY-04336
Species: Discosoma sp
Expression System: E. coli
Tau-F Protein, Human, Recombinant
TMPJ-00828
Species: Human
Expression System: E. coli
NOTCH2NL Protein, Human, Recombinant (mFc)
TMPY-05028
Species: Human
Expression System: HEK293 Cells
EpCAM/TROP1 Protein, Mouse, Recombinant (hFc)
TMPJ-00200
Species: Mouse
Expression System: HEK293 Cells
STUB1 Protein, Human, Recombinant
TMPJ-01386
Species: Human
Expression System: E. coli
MSH2 Protein, Human, Recombinant (His & GST)
TMPY-04267
Species: Human
Expression System: Baculovirus Insect Cells
EGLN1 Protein, Human, Recombinant (His & Myc)
TMPH-01280
Species: Human
Expression System: E. coli
ADAR Protein, Human, Recombinant (His & SUMO)
TMPH-01248
Species: Human
Expression System: E. coli
DAG1 Protein, Human, Recombinant (His & Myc)
TMPH-01258
Species: Human
Expression System: Baculovirus Insect Cells
BRCC3 Protein, Human, Recombinant (His & SUMO)
TMPH-01621
Species: Human
Expression System: E. coli
HAPLN1 Protein, Human, Recombinant (His)
TMPY-00819
Species: Human
Expression System: HEK293 Cells
SARS-CoV-2 Helicase Protein (His & MBP)
TMPJ-01450
Species: SARS-CoV-2
Expression System: E. coli
ANP32A Protein, Human, Recombinant (His & GST)
TMPY-01927
Species: Human
Expression System: E. coli
HIST1H3A Protein, Human, Mouse, Recombinant
TMPY-01332
Species: Human,Mouse
Expression System: E. coli
OMA1 Protein, Human, Recombinant (His & SUMO)
TMPH-01664
Species: Human
Expression System: E. coli
GADD45A Protein, Human, Recombinant (His & GST)
TMPY-02150
Species: Human
Expression System: Baculovirus Insect Cells
TRAIP Protein, Human, Recombinant (His)
TMPH-01270
Species: Human
Expression System: E. coli
JNK2 Protein, Human, Recombinant (His)
TMPY-04550
Species: Human
Expression System: Baculovirus Insect Cells
DDX39B Protein, Human, Recombinant (GST)
TMPH-02133
Species: Human
Expression System: E. coli
PLD6 Protein, Human, Recombinant (His)
TMPH-01689
Species: Human
Expression System: E. coli
カタログ番号 製品名
L7820 High Solubility Micro Fragment Library

1081 compounds
The compound library of highly soluble micro-fragments consists of 1081 low-molecular-weight fragments.
L9610 Cyclic Peptide Library

55 compounds
55 species of cyclic peptide molecules for high-throughput and high-content screening;
L3510 Methylation Compound Library

128 compounds
128 methylation-related compounds that can be used for high-throughput and high-content screening.
L9900 Inactive Ingredient Library

182 compounds
L5100 Fluorochemical Library

574 compounds
A unique collection of 574 fluorochemicals that can be used for high through-put screening (HTS) and high content screening (HCS);
L1310 Cytoskeletal Signaling Pathway Compound Library

759 compounds
A unique collection of 759 cytoskeleton-related compounds, can be used for HTS and HCS;