Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Tetrahydroxystilbene-2-O-β-D-glucoside (EH-201) is a low MW inducer of erythropoietin. Tetrahydroxystilbene-2-O-β-D-glucoside induces expression of erythropoietin, PPAR-γ coactivator 1α (PGC-1α) and haemoglobin in astrocytes and PC12 neuronal-like cells. In vivo, Tetrahydroxystilbene-2-O-β-D-glucoside treatment restores memory impairment, as assessed by the passive avoidance test, in SD, Aβ and KA mouse models. In the hippocampus of mice given Tetrahydroxystilbene-2-O-β-D-glucoside in their diet, levels of erythropoietin, PGC-1α and haemoglobin were increased. Treatment with Tetrahydroxystilbene-2-O-β-D-glucoside might be a therapeutic strategy for memory impairment in neurodegenerative disease, physiological ageing or traumatic brain injury.
説明 | Tetrahydroxystilbene-2-O-β-D-glucoside (EH-201) is a low MW inducer of erythropoietin. Tetrahydroxystilbene-2-O-β-D-glucoside induces expression of erythropoietin, PPAR-γ coactivator 1α (PGC-1α) and haemoglobin in astrocytes and PC12 neuronal-like cells. In vivo, Tetrahydroxystilbene-2-O-β-D-glucoside treatment restores memory impairment, as assessed by the passive avoidance test, in SD, Aβ and KA mouse models. In the hippocampus of mice given Tetrahydroxystilbene-2-O-β-D-glucoside in their diet, levels of erythropoietin, PGC-1α and haemoglobin were increased. Treatment with Tetrahydroxystilbene-2-O-β-D-glucoside might be a therapeutic strategy for memory impairment in neurodegenerative disease, physiological ageing or traumatic brain injury. |
植物由来 |
別名 | tetrahydroxyl diphenylethylene-2-o-gluco, EH-201 |
分子量 | 406.38 |
分子式 | C20H22O9 |
CAS No. | 55327-45-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/mL (147.65 mM)
You can also refer to dose conversion for different animals. 詳細
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Tetrahydroxystilbene-2-O-β-D-glucoside 55327-45-2 Others tetrahydroxyl diphenylethylene-2-o-gluco EH 201 Tetrahydroxystilbene2OβDglucoside Tetrahydroxystilbene-2-O-b-D-glucoside EH201 Tetrahydroxystilbene 2 O β D glucoside Tetrahydroxystilbene-2-O-beta-D-glucoside EH-201 Inhibitor inhibitor inhibit