Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Tipepidine hydrochloride is a reversible inhibitor of dopamine (DA) D2 receptor-mediated GIRK currents (IDA(GIRK)) (IC50: 7.0 μM), with antidepressant-like effect.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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2 mg | 在庫あり | ¥ 9,000 | |||
5 mg | 在庫あり | ¥ 15,000 | |||
10 mg | 在庫あり | ¥ 22,500 | |||
25 mg | 在庫あり | ¥ 40,000 | |||
50 mg | 在庫あり | ¥ 66,500 | |||
100 mg | 在庫あり | ¥ 104,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 16,000 |
説明 | Tipepidine hydrochloride is a reversible inhibitor of dopamine (DA) D2 receptor-mediated GIRK currents (IDA(GIRK)) (IC50: 7.0 μM), with antidepressant-like effect. |
ターゲット&IC50 | D2:7.0 μM |
In vivo | In ACTH-treated rats, Tipepidine (i.p.; 10-40 mg/kg; 0.5-23 hours) significantly decreases the immobility time in the forced swimming test. In ACTH-treated rats, Tipepidine (i.p.; 40 mg/kg) increases the extracellular dopamine level of the nucleus accumbens (NAc) [2]. |
分子量 | 311.89 |
分子式 | C15H18ClNS2 |
CAS No. | 1449686-84-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 50 mg/mL (160 mM)
DMSO: 41.67 mg/mL (133.60 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Tipepidine hydrochloride 1449686-84-3 GPCR/G Protein Membrane transporter/Ion channel Neuroscience Dopamine Receptor Potassium Channel KcsA inhibit Tipepidine Inhibitor Tipepidine Hydrochloride inhibitor