Powder: -20°C for 3 years | In solvent: -80°C for 1 year
UCPH-101 is an inhibitor of excitatory amino acid transporter subtype 1 (EAAT1) with an IC50 of 0.66 μM.
説明 | UCPH-101 is an inhibitor of excitatory amino acid transporter subtype 1 (EAAT1) with an IC50 of 0.66 μM. |
ターゲット&IC50 | EAAT1:0.66 μM. |
In vitro | Preincubation with 100 μM UCPH-101 results in a notable reduction in the expression levels of HA-EAAT1 and HA-GLAST. Additionally, UCPH-101 and UCPH-102 exhibit concentration-dependent inhibition of EAAT1 anion currents, with dissociation constant (KD) values of 0.34±0.03 μM (Hill=1.3±0.13, n≥9) for UCPH-101 and 0.17±0.02 μM (Hill=0.97±0.11, n≥7) for UCPH-102. |
別名 | UCPH 101 |
分子量 | 422.48 |
分子式 | C27H22N2O3 |
CAS No. | 1118460-77-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10.6 mg/mL(25 mM)
You can also refer to dose conversion for different animals. 詳細
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UCPH-101 1118460-77-7 Metabolism transporter inhibit UCPH101 Inhibitor UCPH 101 inhibitor