Powder: -20°C for 3 years | In solvent: -80°C for 1 year
WEE1-IN-3 (JUN76288) is a potent Wee1 kinase inhibitor with an IC50 of <10 nM. It treatment of cancer and other proliferative diseases.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 30,500 | |||
5 mg | 在庫あり | ¥ 74,500 | |||
10 mg | 在庫あり | ¥ 126,500 | |||
25 mg | 在庫あり | ¥ 203,500 | |||
50 mg | 在庫あり | ¥ 280,000 | |||
100 mg | 在庫あり | ¥ 374,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 78,000 |
説明 | WEE1-IN-3 (JUN76288) is a potent Wee1 kinase inhibitor with an IC50 of <10 nM. It treatment of cancer and other proliferative diseases. |
ターゲット&IC50 | Wee1:<10 nM |
In vitro | WEE1-IN-3 inhibits cancer cell growth with IC50 values of 100-1000 nM and <100 nM for SW480 cells and H23 cells, respectively. ?WEE1 is overexpressed in various cancer types,?WEE1 kinase plays a role in the G2-M cell-cycle checkpoint arrest for ?ΝΑ repair before mitotic entry.?Normal cells repair damaged DNA during GI arrest.?Cancer cells often have a deficient G i-S checkpoint and depend on a functional G2-M checkpoint for DNA repair. |
別名 | JUN76288 |
分子量 | 497.59 |
分子式 | C28H31N7O2 |
CAS No. | 2272976-28-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 250 mg/mL (502.42 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
WEE1-IN-3 2272976-28-8 Cell Cycle/Checkpoint Wee1 WEE1IN3 JUN76288 cycle Inhibitor inhibit cell JUN 76288 JUN-76288 WEE-1-IN-3 WEE1 IN 3 Anticancer inhibitor