Powder: -20°C for 3 years | In solvent: -80°C for 1 year
WRG-28 is a potent and selective, allosteric discoidin domain receptor 2 (ddr2) inhibitor(IC50 : 230 nM)
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 9,500 | |||
5 mg | 在庫あり | ¥ 20,500 | |||
10 mg | 在庫あり | ¥ 34,000 | |||
25 mg | 在庫あり | ¥ 72,000 | |||
50 mg | 在庫あり | ¥ 121,500 | |||
100 mg | 在庫あり | ¥ 176,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 22,500 |
説明 | WRG-28 is a potent and selective, allosteric discoidin domain receptor 2 (ddr2) inhibitor(IC50 : 230 nM) |
ターゲット&IC50 | DDR2:230 nM (IC50) |
In vitro | WRG-28 is a selective, extracellularly acting small molecule inhibitor of DDR2 that uniquely inhibits receptor-ligand interactions via allosteric modulation of the receptor.?By targeting DDR2, WRG-28 inhibits tumor invasion and migration, as well as tumor-supporting roles of the stroma, and inhibits metastatic breast tumor cell colonization in the lungs. |
分子量 | 410.44 |
分子式 | C21H18N2O5S |
CAS No. | 1913291-02-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 15 mg/mL (36.55 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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WRG-28 1913291-02-7 Tyrosine Kinase/Adaptors Discoidin Domain Receptor (DDR) WRG 28 WRG28 4T1 breast cancer cells joint destruction breast cancer Discoidin Domain Receptor BT549 CAFs HEK293 Inhibitor inhibit rheumatoid arthritis inhibitor