Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ZL0580 induces HIV suppression by inhibiting Tat transactivation and transcription elongation as well as by inducing repressive chromatin structure at the HIV promoter.
説明 | ZL0580 induces HIV suppression by inhibiting Tat transactivation and transcription elongation as well as by inducing repressive chromatin structure at the HIV promoter. |
In vitro |
In PBMCs of viremic HIV-infected individuals,ZL0580 (8 μM, 2 days) induces HIV transcriptional suppression with low toxicity[1]. ZL0580 treatment (10 μM) suppresses both PMA-stimulated and basal HIV transcription[1]. |
分子量 | 532.53 |
分子式 | C25H23F3N4O4S |
CAS No. | 2377151-10-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 250 mg/mL (469.46 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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ZL0580 2377151-10-3 Chromatin/Epigenetic Microbiology/Virology Proteases/Proteasome HIV Protease Epigenetic Reader Domain HIV Inhibitor ZL-0580 ZL 0580 Human immunodeficiency virus low inhibit PBMC toxicity inhibitor