Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Asundexian (BAY-2433334) is a potent and orally active inhibitor of the coagulation factor FXIa that directly and reversibly binds to the active site of FXIa, thereby inhibiting its activity.Asundexian has an IC50 of 1 nM for human FXIa in buffer.Asundexian has antitumor activity and may be useful in studies of Acute ischemic stroke, transient ischemic attack and ischemic stroke.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 43,500 | |||
5 mg | 在庫あり | ¥ 110,000 | |||
10 mg | 在庫あり | ¥ 165,500 | |||
25 mg | 在庫あり | ¥ 282,500 | |||
50 mg | 在庫あり | ¥ 427,000 | |||
100 mg | 在庫あり | ¥ 647,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 121,500 |
説明 | Asundexian (BAY-2433334) is a potent and orally active inhibitor of the coagulation factor FXIa that directly and reversibly binds to the active site of FXIa, thereby inhibiting its activity.Asundexian has an IC50 of 1 nM for human FXIa in buffer.Asundexian has antitumor activity and may be useful in studies of Acute ischemic stroke, transient ischemic attack and ischemic stroke. |
ターゲット&IC50 | FXIa (human):1 nM |
In vivo | Asundexian displays potent anticoagulant activity in vitro in human and rabbit plasma and antithrombotic efficacy in vivo in a rabbit arterial thrombosis model.[1] |
別名 | BAY 2433334, Asundexian, BAY2433334, BAY-2433334 |
分子量 | 592.93 |
分子式 | C26H21ClF4N6O4 |
CAS No. | 2064121-65-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 118.59 mg/mL (200 mM)
You can also refer to dose conversion for different animals. 詳細
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Asundexian 2064121-65-7 Metabolism Factor Xa BAY 2433334 BAY2433334 BAY-2433334 Inhibitor inhibitor inhibit