Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Darexaban (Tanexaban, YM-150) is a direct inhibitor of Factor Xa.Darexaban and Darexaban glucuronide selectively and competitively inhibit FXA and inhibit prothrombin activity at the site of blood clot (thrombus) formation. This leads to a reduction in blood clot formation in a dose-dependent manner. Reducing clotting will reduce blockages in blood flow, which may reduce the risk of myocardial infarction, unstable angina, venous thrombosis, and ischemic stroke.
説明 | Darexaban (Tanexaban, YM-150) is a direct inhibitor of Factor Xa.Darexaban and Darexaban glucuronide selectively and competitively inhibit FXA and inhibit prothrombin activity at the site of blood clot (thrombus) formation. This leads to a reduction in blood clot formation in a dose-dependent manner. Reducing clotting will reduce blockages in blood flow, which may reduce the risk of myocardial infarction, unstable angina, venous thrombosis, and ischemic stroke. |
ターゲット&IC50 | FXa:54.6 nM |
別名 | YM 150, Darexaban, Tanexaban, YM150 |
分子量 | 474.55 |
分子式 | C27H30N4O4 |
CAS No. | 365462-23-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 245 mg/mL (516.28 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Darexaban 365462-23-3 Metabolism Factor Xa Serine endopeptidases time YM-150 YM 150 Ser/Thr Protease Fxa oral antithrombotic Inhibitor prothrombin Serine proteases Threonine proteases Darexaban, Tanexaban anticoagulant YM150 inhibit inhibitor