store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Butylchlorogenate is a natural compound isolated from Lonicera japonica, Urceola rosea.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 45,000 | |||
5 mg | 在庫あり | ¥ 112,500 | |||
10 mg | 在庫あり | ¥ 164,000 | |||
25 mg | 在庫あり | ¥ 250,500 | |||
50 mg | 在庫あり | ¥ 340,000 | |||
100 mg | 在庫あり | ¥ 454,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 122,500 |
説明 | Butylchlorogenate is a natural compound isolated from Lonicera japonica, Urceola rosea. |
In vitro | Butyl chlorogenate were evaluated for their inhibitory activity against melanogenesis in α-MSH-stimulated B16 melanoma cells, five caffeoylquinic acids, i.e. Butyl chlorogenate exhibited inhibitory activities with 33-62% reduction of melanin content at 100 μM concentration with no or almost no toxicity to the cells (89-114% of cell viability at 100 μM). Western blot analysis showed that Butyl chlorogenate reduced the protein levels of microphtalmia-associated transcription factor (MITF), tyrosinase, tyrosine-related protein 1 (TRP-1), and TRP-2 mostly in a concentration-dependent manner, suggesting that this compound inhibits melanogenesis on α-MSH-stimulated B16 melanoma cells by, at least in part, inhibiting the expression of MITF, followed by decreasing the expression of tyrosinase, TRP-1, and TRP-2.[1] |
分子量 | 410.42 |
分子式 | C20H26O9 |
CAS No. | 132741-56-1 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 4.11 mg/mL (10 mM)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Butyl chlorogenate 132741-56-1 Others Inhibitor inhibitor inhibit